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The software has been developed in Smalltalk80 [1] on SUN and Apple Macintosh computers. Smalltalk80 is an object-oriented programming system which permits rapid prototyping. The need for prototyping in the specification of general practitioner systems was highlighted as long ago as 1980 [4] and is essential to the user -centred philosophy of the project. The goal is a hardware independent system usable on any equipment capable of supporting an integrated environment for handling both textual and graphics and 'point and select' interaction. The architecture is extensible and provides a platform for future experimention with technical advances such as touch screens and voice technology. User Interface Management Systems (UIMS) technology is developing rapidly offering a number of techniques which allow the abstract design of the interface to be separated from the screen/display management on one hand and the internal workings of the application on the other. [2] The importance of this 'layered' approach is that such techniques enable the user to tailor the application to his/her individual preferences and the design team has included and developed many of these ideas into the design. 7. Conclusion: Value Added to Health.

This fact has become particularly obvious in the last few years through the employment of nev short-lived radionuclides, new technical procedures and data processing. For technical reasons the x-camera is developing in the direction of mea suring mainly the so-ca~led 'soft' I-emitters at the present time.

Organized in Cooperation with BMIS, British Medical Informatics Society

The continuing growth of computed tomography (CT) and other imaging techniques motivated us to bring together a comprehensive review of the state of the art in diagnostic imaging.

The corresponding term medical inforaatics, now used in the name of international societies such as the "International Medical Informatics Association", covers "medical computer science", "medical information science", as well as "biomedical engineering" and has no de finite boundary to "biomathematics".

In diagnostic medicine a large part of information about the patient is drawn from data, which, more or less, are represented in an opti calor pictorial form. by Computer tomography or Computer angio graphy (image processing) . Management of the steeply rising amount of medical image data in the hospital (image data bases) .

This book contains 26 papers describing research in the do-main of Artificial Intelligence in Medicine. The papers aregrouped around the following themes: Methodology, knowledgerepresentation, clinical applications, modelling, uncertain-ty management, knowledge acquisition, and the user perspec-tive.

For over a decade, Working Group 8 (Nursing) of the International Medical Informatics Association has sponsored, in conjunction with a host country, a triennial international symposium on nursing informatics. Each conference consists of a main conference and an invitational working conference following the main event.

The Fourth International "Nursing Informatics '91" Preconference sessions held in Melbourne Australia on the 12th and 13th April 1991 hosted by the Nursing Computer Group, Victoria Inc.

In the previous year, 1839, the American Journal of Dental Science was initiated as the first periodic scientific and professional publication in dentistry, later evolving to the Journal of the American Dental Association.

Medical information systems such as Radiology Management Information Systems (RIS), Picture Archiving and Communications (PACS) and Hospital Information Systems (HIS) will soon be standard tools to support routine work in hospitals.

Organized in Cooperation with IIRIAM, International Institute of Robotics and Artificial Intelligence, Marseille, France

As research on expert systems has moved well into its second decade, it has become popular to cite the limitations of the phenomenologic or associational approach to knowledge representation that was typical of first generation systems.

The Working Group 5 of the International Medical Informatics Associ ation (IMIA) dedicates its work to information systems in primary and ambulatory care.

The Working Group 5 of the International Medical Informatics Associa tion (IMIA) is dedicated to information systems in primary care with special emphasis on computer systems in the doctor's office.

The seminar had three objectives: 1) to discuss the state of the art of biomedical image processing with emphasis on four themes: microscopic image analysis, radiological image analysis, tomography, and image processing technology;

As a hospital physician it is impossible to escape the notion that the difficult medical problems one encounters are also being confronted by other' physicians throughout the world. One serious consequence of these characteristics of the medical literature is that patients are largely overtreated.

The papers gathered in this volume were presented at the medical sessions of the First Conference on Mathematics at the Service of Man held in Barcelona, Spain, July 11-16, 1977.

Adverse side-effects of oral contraception become only apparent in later life and probably only after a latent interval of at least 10 years. Up to now about 40 % of the women aged 35 years or older have no experience with the pill. The pilot phase of a German long-term study began three years ago.

An intent to assemble a private report became an attempt to write a public monograph when it was discovered that the leaders of the Stockholm project had aspired for some time to put their work more cohesively in the public domain.

This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The most important features are: - A new view on the per-litter analysis problem in em- bryotoxicity assays. - A highly sophisticated treatment of the so-called muta-tox problem in mutagenicity assays.