Medicinsk mikrobiologi og virologi

Virus har sat dagsordenen i Jens Lundgrens arbejdsliv, lige siden han som helt ung læge stod ved sygesengen hos dødsmærkede aidspatienter og forskede i at finde en effektiv medicinsk mehandling til dem. Resultatet kan alverdens hiv-patienter takke ham for i dag.Siden coronapandemiens start har han knoklet for at hjælpe livstruede patienter og udvikle nye behandlinger med videnskabeligt dokumenteret effekt. Han har rådgivet de danske sundhedsmyndigheder og regeringen, og han har arbejdet tæt sammen med toppen af det amerikanske sundhedsvæsen under pandemigeneralen Anthony Fauci.I Vild virus giver han et unikt indblik i, hvad der sker bag kulisserne, når en virus truer os på livet og vender op og ned på vores hverdag. Bogen giver den første samlede beretning om de to vilde pandemiår: forskernes kapløb med tiden og en virus, der er en mester i at mutere, håndteringen af alle de udfordringer, virus pludselig kastede os ud i – og hvad vi har lært, så vi kan være bedre forberedte, når den næste virus udfordrer vores eksistens. For det vil ske: Pandemiernes tid er langtfra forbi.Bogen er blevet til i tæt samarbejde med Lars Igum Rasmussen, der som sundhedsredaktør på Politiken har dækket coronapandemien med mere end 200 nyhedsartikler, interviews, reportager og analyser.

Hvordan forårsager mikroorganismer sygdomme som fødevareforgiftning, ebola, borreliose og rævebændelorm? Og hvordan udnyttes andre mikroorganismer som Saccharomyces, E. coli og probiotiske bakterier i madlavning, i produktion af øl og i kroppens tarmsystem?Mikrobiologi giver en god forståelse af de forskellige mikroorganismer, deres vækst, deres funktioner samt deres rolle i fødevareproduktion. Bogens første del indeholder en grundig gennemgang af den moderne systema- tiske bakteriologi, og derudover beskrives virus, svampe, protozoer og parasitter. Anden del af bogen giver en grundig indføring i fødevarernes produktion, mikro- biologiske risici samt konserveringsmetoder, og hvordan man kan arbejde med fødevaresikkerhed, så mikroorganismerne ikke udgør en sundhedsrisiko.Bogens målgrupper er studerende ved korte og mellemlange videregående uddannelser på det sundhedsfaglige, fødevareteknologiske, laboratorietekniske og procesteknologiske område samt mindre produktioner/virksomheder, der arbejder med mikrobiologi. Bogen kan også anvendes til temaundervisning i fx biologi eller bioteknologi i gymnasiet. Desuden kan den benyttes som opslagsværk for særligt mikrobiologiinteresserede. Endelig kan mindre fødevarevirksomheder have gavn af kapitlerne om hygiejne, egenkontrol og fødevaresikkerhed.Denne 5. udgave er ajourført og grundigt revideret. Der er blandt andet tilføjet afsnit om biofilm og tarmbakterier. Desuden er kapitlerne om fødevaresikkerhed blevet udvidet, således at de kan bruges som opslagsværk af fødevarevirksom- heder. Endelig er bogen blevet opdateret med et helt nyt layout.

Mikrobiologikortene hjælper dig med at huske information om de forskellige pensumrelevante humanpatogene mikroorganismer, når du skal læse til eksamen i mikrobiologi på medicinstudiet. Der er 163 kort, som du kan repetere alene eller med en læsemakker. Hver mikroorganisme er repræsenteret ved et kort, som i kondenseret form oplyser om karakteristika, infektioner, forekomst, smitteveje, diagnostik og forslag til behandling. Der medfølger desuden grendiagram-oversigter over de forskellige bakterier, virus, svampe og parasitter.

Kompendium i Mikrobiologi & Infektionsmedicin illustrerer og forklarer de fundamentale koncepter og begreber indenfor mikrobiologi og infektionsmedicin, herunder de vigtigste mikroorganismer og deres respektive sygdomme. Kompendiet er målrettet studerende på de sundhedsfaglige uddannelser, herunder medicin og odontologi. Kompendiet er et godt alternativ til de tunge lærebøger, da pensum præsenteres på en kort og overskuelig måde, samtidig med at detaljegraden, der forventes til eksamen, er bibeholdt. Herudover dækker kompendiet den eksamensrelevante teori og de laboratoriemetoder, som gennemgås i det mikrobiologiske øvelseskursus.

Resistente bakterier er blevet en større trussel langt hurtigere, end eksperterne hidtil har forudset det. Studier peger på, at resistente bakterier i 2050 vil tage livet af lige så mange mennesker som for eksempel kræftsygdomme.Da Alexander Fleming i 1928 opdagede antibiotika, revolutionerede det lægevidenskaben. Her små hundrede år efter er vi ved at sætte hele fremskridtet over styr. Ifølge professor i mikrobiologi Hans Jørn Kolmos er det nødvendigt med en anden tilgang til udviklingen og ikke mindst brugen af antibiotika i sundhedsvæsenet og landbruget, hvis vi i fremtiden vil undgå, at helt almindelige infektioner kan blive livstruende.Hans Jørn Kolmos (f. 1948) er professor på Syddansk Universitet og tidligere overlæge på Klinisk Mikrobiologisk Afdeling på Odense Universitetshospital, hvor han blandt andet har ledet forskningen i MRSA. Kolmos er vokset op på en stor gård ved Toftlund i Sønderjylland, og slægten har drevet landbrug i flere hundrede år.Moderne Ideer er støttet af Lundbeckfonden, Augustinus Fonden og Statens Kunstfond. I bøgerne gør førerende forskere deres viden tilgængelig og leverer deres bud på, hvordan vi løser tidens største udfordringer.

Denne bog er et læringsværktøj til studerende, som gennem øvelser, opgaver og refleksionsspørgsmål kan øve sig i at træffe kliniske beslutninger inden for det infektionshygiejniske felt.Formålet med bogen er at skabe forståelse af, at klinisk beslutningstagning i en infektionshygiejnisk sammenhæng er en kompleks og interagerende proces, der sker på baggrund af både viden, erfaringer og den aktuelle situation. Bogen består af to dele:Del 1 indeholder en teoretisk gennemgang af de metoder og modeller, som anvendes i bogen. Det drejer sig om den infektionshygiejniske kliniske beslutningstagen, som struktureres af den pædagogiske refleksionsmodel (PRM) samt medicinsk teknologivurdering (MTV).Del 2 består af syv virkelighedsnære cases. Hver case indeholder en række infektionshygiejniske problemstillinger, og via refleksionsspørgsmål og øvelser guides den studerende i, hvordan man kan omsætte teoretisk viden til handlinger i praksis.Målgruppen for bogen er studerende, som i forbindelse med deres arbejde skal træffe infektionshygiejniske kliniske beslutninger inden for sundheds- og socialområdet. Bogen kan desuden bruges som supplerende teoretisk opslagsværk for uddannede sundhedsprofessionelle.

VACCINER ER VORES VENTakket være vacciner frygter vi i dag ikke sygdomme som kopper, mæslinger, stivkrampe eller børnelammelser. Det er en sundhedsrevolution.I denne bog følger vi de to erfarne overlæger og virologer Anders Lars Peter i en rejsevaccinationsklinik, og det går ikke stikke for sig. Du kommer sprøjtende igennem vaccineimmunitet og alle vaccinerne – fra de dræbte og de levende til de nye genetiske og alt derimellem – deres særlige historier, anvendelse (for og imod) samtid fortid og fremtid.Bogen er en hyldest til de videnskabelige triumfer der har formet vores sundhed gennem årtier. Et lille stik, det er ikke noget at være bange for.

Berry Fruits: Bioactives, Health Effects and Processing, Volume Eight in the Developments in Food Quality and Safety series, covers the most recent research on bioactives of berries, improvement of bioavailability and bioaccessibility of berry bioactives, processing of berries, and production of functional food ingredients obtained from berries. In eleven chapters, the book addresses, in detail, advanced technological applications in the sustainable production of berries, as well as bioactives/food ingredients obtained from berries. In addition, the book covers developments in novel processes for berries sustainable production, along with valorization of wastes and by-products of berry processing.The series is authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

A pacy, real-life page-turner by Reuters journalist on the global 100-days mission to identify and catch the next virus outbreak, codenamed DISEASE X, before it spreads worldwide.

This volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed.Helicobacter pylori is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world¿s population. H. pylori and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by thisbacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer-related death worldwide. H. pylori is the first bacterium that has been classified as a type-I carcinogen by the International Agency for Research on Cancer (IARC). Recent research progress identified crucial bacterial, host and environmental factors which control H. pylori-induced gastric malignancy. New studies also suggest that specific human germline mutations and other genetic aberrations have an important impact on H. pylori-induced pathology. In this volume, all these recently discovered mechanisms are reviewed in the light of gastric cancer development, and H. pylori epidemiology, virulence factors, immune evasion, pathophysiology, cancer signalling and novel therapeutic protocols are presented. This volume is aimed at researchers in the fields of immunology, genetics, microbiology and medicine who are interested in the detailed mechanisms of the pathogenicity of this carcinogenic stomach bacterium.

This book will explore the knowledge of current diagnostic automation techniques applied in the field of clinical microbiology, tropical diseases, POCT, etc. There is no such type of book related to this topic. This book will help clinicians, microbiologists, and researchers to make diagnostic algorithms for infectious diseases and help them in early diagnosis. Automation in clinical microbiology has revolutionized routine practice in diagnostic cum research in medical microbiology. This book covers the recent updates and advances in diagnostic microbiology and provides new techniques related to Genomic, Proteomic, and metabolomics in microbiology. This book will intensely discuss the new and innovative automation techniques available for diagnosis in the microbiology laboratory. This book is more focused on automation techniques, which are used in the early detection of infectious diseases even caused by rare microorganisms. Furthermore, this book has complied with the chapters that provide insights to readers with comprehensive and usable knowledge on automation techniques in diagnostic microbiology.

This second edition provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols,  Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antibiotics: Methods and Protocols, Second Edition aims to inspire scientific work in the exciting field of antibiotic research.

Infectious diseases play a vital role in the field of internal medicine, and understanding their importance is crucial for students pursuing a career in this field. In this subchapter, we will explore why infectious diseases are significant and how they impact the field of internal medicine.First and foremost, infectious diseases are essential to study because they are a significant cause of illness and mortality worldwide. From common infections like the flu to more severe diseases like tuberculosis and HIV/AIDS, infectious diseases affect millions of people annually. By understanding the pathogens responsible for these diseases, medical professionals can develop effective prevention strategies, diagnostic tools, and treatment protocols. This knowledge is invaluable in managing and controlling infectious diseases, ultimately saving lives.Moreover, infectious diseases have a profound impact on public health. Outbreaks and epidemics can lead to a substantial burden on healthcare systems, affecting entire populations. By studying infectious diseases, students can learn about surveillance systems, outbreak investigations, and the implementation of control measures to prevent the spread of diseases within communities. This knowledge allows for efficient and timely responses to outbreaks, minimizing their impact on public health.Understanding infectious diseases is also essential in the context of antimicrobial resistance (AMR). The misuse and overuse of antibiotics have led to the development of drug-resistant bacteria, making the treatment of infections more challenging. Students studying internal medicine need to be aware of this growing threat and learn about strategies to combat AMR. By promoting proper antibiotic stewardship, medical professionals can help slow down the emergence of drug-resistant infections and preserve the efficacy of available antimicrobial agents.In addition to their clinical significance, infectious diseases have a social and economic impact. Outbreaks can disrupt economies, strain healthcare systems, and cause fear and panic among populations. By studying infectious diseases, students can understand the social determinants of health, the cultural aspects influencing disease transmission, and the importance of effective communication in managing outbreaks. This knowledge can help medical professionals address the broader implications of infectious diseases and work towards building resilient and responsive healthcare systems.

This book, Gut microbiome and Brain Ageing, deals with the mechanisms and phenomenon that relates gut microbiome and aging of the brain. This book will bring forth the connection between good gut and brain aging and includes some cutting edge research topics dealing with gut physiology and its importance as future therapeutic option in neurological disorders. The gut microbiome's impact on neuronal function, mediated by neurotransmitters, vitamins, and neuroactive microbial metabolites, is an exciting area of investigation that this book thoroughly explores. It also covers the pivotal role of the gut microbiome in the etiology of various neurodegenerative disorders such as Alzheimer¿s disease (AD), Parkinson¿s disease (PD), depression, or multiple sclerosis (MS). It also explores the expanding understanding of the importance of the early-life gut microbiota and its implications for long-term health consequences. This book primarily addresses researchers, clinicians, and doctoral andgraduate students working in biomedicine, neurobiology, nutrition, microbiology, and translational medicine streams.

This textbook provides an up-to-date overview of the most important parasites in humans and their potential vectors. For each parasite, the book offers a concise summary including its distribution, epidemiology, life cycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures. Numerous tables, diagrams and over 200 colorful illustrations highlight the main aspects of parasitic infestations and present suitable control measures. 60 questions help to test readers' theoretical knowledge of the field. In short, the book is highly recommended for anyone looking to delve into the field of human parasitology. It is intended for students of biology and human medicine, medical doctors, pharmacists and laboratory staff alike. Furthermore, persons who plan to visit or live longer in endemic regions will find essential information on necessary preventive and control measurements.

"Comprehensive up-to-date guide to clinical and diagnostic virology. Individual chapters cover viruses from A-Z, which are then grouped under syndromes. Liberal use of tables and algorithms enable quick access to key information. An ideal introduction for interested trainees and a practical reference for more experienced hospital clinicians and GPs"--