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This book introduces the fundamentals of deep learning for biomedical image analysis for applications including ophthalmology, cancer detection and heart disease. The book discusses multimedia data analysis algorithms and the principles of feature selection, optimisation and analysis.
Breast cancer is the neoplasia with the highest incidence in the female population worldwide. Cancer originates from breast tissue, most commonly from the inner lining of milk ducts or the lobules. Histologic type, tumor grade and size, expression of ER, PR, and HER2 receptors, and lymph node and metastasis status are considered important prognostic factors. This book provides a comprehensive overview of breast cancer with chapters on breast cancer markers, breast cancer in different populations, imaging, minimally invasive techniques, breast reconstructive surgery, and much more.
With rise of smart medical sensors, cloud computing and the health care technologies, "e;connected health"e; is getting remarkable consideration everywhere. Recently, the Internet of Things (IoT) has brought the vision of a smarter world into reality. Cloud computing fits well in this scenario as it can provide high quality of clinical experience. Thus an IoT-cloud convergence can play a vital role in healthcare by offering better insight of heterogeneous healthcare content supporting quality care. It can also support powerful processing and storage facilities of huge data to provide automated decision making. This book aims to report quality research on recent advances towards IoT-Cloud convergence for smart healthcare, more specifically to the state-of-the-art approaches, design, development and innovative use of those convergence methods for providing insights into healthcare service demands. Students, researchers, and medical experts in the field of information technology, medicine, cloud computing, soft computing technologies, IoT and the related fields can benefit from this handbook in handling real-time challenges in healthcare. Current books are limited to focus either on soft computing algorithms or smart healthcare. Integration of smart and cloud computing models in healthcare resulting in connected health is explored in detail in this book.
This book highlights the different aspects of the research project ¿E4C Horizon 2020 European Project¿ aimed at fighting the coronavirus by combining the best supercomputing resources and artificial intelligence with state-of-the-art experimental facilities up through clinical validation.Coronavirus disease has become an important public issue across the globe since December 2019. There is an urgent need to develop potent anti-COVID-19 agents for the prevention of the outbreak and stop viral infections.To this aim, a public¿private consortium composed by European and national infrastructures, center of excellence, universities, and a pharmaceutical company started the E4C Horizon 2020 EuropeanProject: Its core idea was to use the EXaSCale smArt pLatform Against paThogEns (EXSCALATE) supercomputing platform for a process known as ¿drug repurposing¿, namely to identify the most promising safe in man drugs for immediate treatment of the already infected population and then novel pan-coronavirus inhibitors to address future emergencies.This ambitious goal exploited a ¿chemical library¿ of 500 billion molecules, thanks to a processing capacity of more than 3 million molecules per second, made available by the computing power of the EXSCALATE platform.
This book presents a collection of high-quality research papers, presented at the Second International Symposium on Bioinformatics and Biomedicine (BioInfoMed¿2022). It offers a comprehensive look into some of the fastest growing fields of science, such as biomedicine, bioinformatics, artificial intelligence, and mathematical modeling. The different chapters of the work include both practical solutions and strictly scientific considerations expanding knowledge about the future bioinformatics and biomedical engineering challenges. We believe that the presented works will have a great impact not only on the development and the application of new methods for modeling, decision making and data mining in healthcare and biomedicine, but also it will provide a source of inspiration for researchers who can implement the proposed methods into their practice and scientific studies.
This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.
This book provides a thorough overview of cutting-edge research on electronics applications relevant to industry, the environment, and society at large. It covers a broad spectrum of application domains, from automotive to space and from health to security, while devoting special attention to the use of embedded devices and sensors for imaging, communication and control. The book is based on the 2022 ApplePies Conference, held in Genoa, Italy in September 2022, which brought together researchers and stakeholders to consider the most significant current trends in the field of applied electronics and to debate visions for the future. Areas addressed by the conference included information communication technology; biotechnology and biomedical imaging; space; secure, clean and efficient energy; the environment; and smart, green and integrated transport. As electronics technology continues to develop apace, constantly meeting previously unthinkable targets, further attention needs to bedirected toward the electronics applications and the development of systems that facilitate human activities. This book, written by industrial and academic professionals, represents a valuable contribution in this endeavor.
Do cephalopods change color when under distress? Is the reptilian heart analogous to a diaphragm positive displacement pump? Are digital twins the answer for animal experimentation? This book explores the new field of veterinary engineering science and discusses how to better measure vital signs in exotic and companion animals. A vast opportunity exists for developing novel technologies that target reductions to the number of invasive procedures patients are subjected to. We examine improvements to animal care and enhancement of animal welfare while creating a more sustainable veterinary healthcare ecosystem. The authors address the challenges engineers face in designing healthcare equipment for animals and how the field of veterinary engineering contributes to traditional veterinary medicine. This book brings a novel field of engineering to train future veterinarians and engineers on design and application of technology to veterinary medicine.Serves as a learning resource for the training and education of veterinary students, veterinarians and engineersDemonstrates through experiments and case studies the merging point between engineering and veterinary medicineDiscusses concepts and issues associated with engineering and veterinary medicineIllustrates veterinary challenges using an engineering-design approachProvides examples of veterinary applications with successful outcomes, incorporating step-by-step directions for engineers
Bone tumour management is a rapidly evolving field, thanks to ongoing successful research. This book is a comprehensive review of selected topics that have seen rapid change over the last decade. Arranged in an easy-read format, it contains three sections: the first discusses general topics pertaining to bone tumours; the second is devoted to breast carcinoma; and a larger final section concerns sarcomas and their management. This book explains complex topics in an easy-to-understand format, elegantly presented by a group of eminent researchers. It is a must-have book for researchers, scientists and clinicians, including medical students, oncologists, orthopaedic surgeons, and anyone who manages bone tumours. The book may serve as a CME (continuing medical education) tool for those wishing to update their knowledge on bone tumours.
Sustainable Material for Biomedical Engineering Application discusses current interdisciplinary approaches in the development of materials and their derivatives that are sustainable for biomedical engineering application. Recent advancement of materials research has shown to have great impact on biomedical and clinical applications. With potential for sustainability, the materials discussed and illustrated in this book, may have the ability to increase and contribute to wider therapeutic options for patients. On the other hand, with the advancement in materials technology, they also have positive impacts in terms of reproducibility and more cost-effective manufacturing solutions for biomedical engineering industry. Some of the main aspects covered in this book are utilisation of human waste, food waste and green technology approach for materials in biomedical engineering applications such as tissue engineering, 3D printing and biosensing. A team of experts from various disciplines share recent advances that provide details and integrates different approaches to sustainable materials development. This book is intended for academicians, researchers, students and industrial players in the field of materials and biomedical engineering.
This book covers computer-integrated equipment manufacturing, which allows high levels of adaptability and rapid equipment design changes to enable smart manufacturing processes. Benefits of the integration of lean manufacturing, smart sensors, 5G technology, IoTs, virtual reality, 3D printing, robotics and automation, are discussed.
This volume provides state-of-the-art methodology to functionalize microtubules and construct microtubule-based materials. Chapters consists of six sections detailing modification of microtubule structures, observation and control of microtubule movement, material applications of microtubules in vitro, development of microtubule-binding molecules, comprehensive approaches to analyze properties of microtubules, and functionalization of microtubules in living cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Microtubules: Methods and Protocols aims to provide useful information for construction of microtubule-based materials and help to create new ideas for the next-generation of materials and applications through detailed protocols.
This book provides a thorough overview of cutting-edge research on electronics applications relevant to industry, the environment, and society at large. It covers a broad spectrum of application domains, from automotive to space and from health to security, while devoting special attention to the use of embedded devices and sensors for imaging, communication and control. The volume is based on the 2021 ApplePies Conference, held online in September 2021, which brought together researchers and stakeholders to consider the most significant current trends in the field of applied electronics and to debate visions for the future. Areas addressed by the conference included information communication technology; biotechnology and biomedical imaging; space; secure, clean and efficient energy; the environment; and smart, green and integrated transport. As electronics technology continues to develop apace, constantly meeting previously unthinkable targets, further attention needs to be directed toward the electronics applications and the development of systems that facilitate human activities. This book, written by industrial and academic professionals, represents a valuable contribution in this endeavor.
This book gathers papers presented at the 8th International Conference on Movement, Health and Exercise (MoHE 2022) with the conference theme "Enhancing Health and Sports Performance by Design". The topics covered include exercise science; human performance; physical activity and health; sports medicine; sports nutrition; management and sports studies; and sports engineering and technology. Its content is of interest to sports scientists, researchers and practitioners from various sports and exercise sub-disciplines.
Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer. This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices.
Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book describes the various smart biomaterial-based treatments available, reviewing how they can be designed to target specific tumor types, adapt to changes in the cell microenvironment and offer smart, personalized therapy for different cancer variants, especially those which are drug-resistant. The book provides a materials-focused look at precision cancer medicine, and is thus useful to materials scientists, biomedical engineers, and biomedical scientists - including cancer and genetic specialists - with an interest in alternative cancer therapies.
Humans are electric beings. We are managed, monitored, and stimulated electrically. This textbook provides students and practitioners with a solid foundation and understanding of human electricity and the work currently being done to further develop electrical signals for medical purposes and related goals. The book introduces the fundamentals of how biological systems generate electrical signals, covering a wide range of biomedical engineering topics including bioelectricity, biomedical signals, neural engineering, and brain-computer interface. The book is presented in three sections: Part I explains how electrical signals and impulses manage the human body; Part II examines the kinds of electrical signals from the human body and how they are monitored, controlled, and used; Part III looks at clinical use of electrical stimulation toward the human body and how they are being developed for interventions in medicine. The book is also a valuable professional reference for practicing engineers and scientists. Explains humans as electric beings who are managed, monitored, and stimulated electrically;Deals with the electricity of major human organs;Covers a wide range of biomedical engineering topics
Microorganisms, viruses, and computer programs encode all the information necessary to reproduce and spread themselves. Yet these mechanisms are amazingly similar in the animate world, in the world of viruses, and even in the world of technical systems. The book shows how great the parallels are between these various animate and inanimate replicating systems and what they are based on.The excursion also leads into the fascinating world of genetics, to the question of what defines life and into the programming of software that multiplies itself independently. Finally, the question is derived whether and to what extent such self-replicating technical systems can become as dangerous as infectious viruses in triggering pandemics, such as the Corona pandemic in 2020.
"Customized Collagen Biosynthesis for Tissue Engineering Applications" by Ilamaran M. is a comprehensive study on the potential of customized collagen biosynthesis for tissue engineering applications.Through detailed research and analysis, Ilamaran M. highlights the role of collagen in tissue engineering and the benefits of customized collagen biosynthesis. He also discusses the latest advancements in the field and the future potential of this technology in regenerative medicine.Whether you are a healthcare professional looking for new approaches to tissue engineering, or a researcher interested in the latest advancements in collagen biosynthesis, "Customized Collagen Biosynthesis for Tissue Engineering Applications" is an essential resource.Order your copy today and discover how customized collagen biosynthesis can revolutionize tissue engineering and regenerative medicine.
This book gathers peer-review contributions to the 5th International Workshop on Gerontechnology, IWoG 2022, held on November 17-18, 2022, in Évora, Portugal, and in Caceres, Spain. They report on cutting-edge technologies and optimized workflows for promoting active aging and assisting older adults at home, as well as in healthcare centers. They discuss the main challenges in the development, use and delivery of health care services and technologies. Besides proposing solutions for improving monitoring and management of health parameters and age-related diseases, the chapters also describe approaches for helping seniors in their daily tasks and facilitating their communication and integration with assistive technologies. All in all, this book provides health professionals, researchers, and service providers with extensive information on the latest trends in the development and application of gerontechnology, with a special emphasis on improving quality of life and socialintegration of the elderly.
Increase in consumer awareness of nutritional habits has placed automatic food analysis in the spotlight in recent years. However, food-logging is cumbersome and requires sufficient knowledge of the food item consumed. Additionally, keeping track of every meal can become a tedious task. Accurately documenting dietary caloric intake is crucial to manage weight loss, but also presents challenges because most of the current methods for dietary assessment must rely on memory to recall foods eaten. Food understanding from digital media has become a challenge with important applications in many different domains. Substantial research has demonstrated that digital imaging accurately estimates dietary intake in many environments and it has many advantages over other methods. However, how to derive the food information effectively and efficiently remains a challenging and open research problem. The provided recommendations could be based on calorie counting, healthy food and specific nutritional composition. In addition, if we also consider a system able to log the food consumed by every individual along time, it could provide health-related recommendations in the long-term.Computer Vision specialists have developed new methods for automatic food intake monitoring and food logging. Fourth Industrial Revolution [4.0 IR] technologies such as deep learning and computer vision robotics are key for sustainable food understanding. The need for AI based technologies that allow tracking of physical activities and nutrition habits are rapidly increasing and automatic analysis of food images plays an important role. Computer vision and image processing offers truly impressive advances to various applications like food analytics and healthcare analytics and can aid patients in keeping track of their calorie count easily by automating the calorie counting process. It can inform the user about the number of calories, proteins, carbohydrates, and other nutrients provided by each meal. The information is provided in real-time and thus proves to be an efficient method of nutrition tracking and can be shared with the dietician over the internet, reducing healthcare costs. This is possible by a system made up of, IoT sensors, Cloud-Fog based servers and mobile applications. These systems can generate data or images which can be analyzed using machine learning algorithms.Image Based Computing for Food and Health Analytics covers the current status of food image analysis and presents computer vision and image processing based solutions to enhance and improve the accuracy of current measurements of dietary intake. Many solutions are presented to improve the accuracy of assessment by analyzing health images, data and food industry based images captured by mobile devices. Key technique innovations based on Artificial Intelligence and deep learning-based food image recognition algorithms are also discussed. This book examines the usageof 4.0 industrial revolution technologies such as computer vision and artificial intelligence in the field of healthcare and food industry, providing a comprehensive understanding of computer vision and intelligence methodologies which tackles the main challenges of food and health processing. Additionally, the text focuses on the employing sustainable 4 IR technologies through which consumers can attain the necessary diet and nutrients and can actively monitor their health. In focusing specifically on the food industry and healthcare analytics, it serves as a single source for multidisciplinary information involving AI and vision techniques in the food and health sector. Current advances such as Industry 4.0 and Fog-Cloud based solutions are covered in full, offering readers a fully rounded view of these rapidly advancing health and food analysis systems.
This book gathers peer-review contributions to the 4th International Workshop on Gerontechnology, IWoG 2021, held on November 23-24, 2021, in Evora, Portugal. They report on cutting-edge technologies and optimized workflows for promoting active aging and assisting elderly people at home, as well as in healthcare centers. They discuss the main challenges in the development, use and delivery of health care services and technologies. Not only they propose solutions for improving in practice the monitoring and management of health parameters and age-related diseases, yet they also describe improved approaches for helping seniors in their daily tasks and facilitating their communication and integration with assistive technologies, thus improving their quality of life, as well as their social integration. All in all, this book provides health professionals, researchers, and service providers with extensive information on the latest trends in the development and practical application of gerontechnology, with a special emphasis on improving quality of life of the elderly.
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