Biomedicinsk teknik

This open access book establishes a dialog among the medical and intelligent system domains for igniting transition toward a sustainable and cost-effective healthcare. The Person-Centered Care (PCC) positions a person in the center of a healthcare system, instead of defining a patient as a set of diagnoses and treatment episodes. The PCC-based conceptual background triggers enhanced application of Artificial Intelligence, as it dissolves the limits of processing traditional medical data records, clinical tests and surveys. Enhanced knowledge for diagnosing, treatment and rehabilitation is captured and utilized by inclusion of data sources characterizing personal lifestyle, and health literacy, and it involves insights derived from smart ambience and wearables data, community networks, and the caregivers¿ feedback. The book discusses intelligent systems and their applications for healthcare data analysis, decision making and process design tasks. The measurement systems and efficiency evaluation models analyze ability of intelligent healthcare system to monitor person health and improving quality of life.

Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.

Artificial Intelligence and Image Processing in Medical Imaging deals with the applications of processing medical images with a view of improving the quality of the data in order to facilitate better decision- making. The book covers the basics of medical imaging and the fundamentals of image processing. It explains spatial and frequency domain applications of image processing, introduces image compression techniques and their applications, and covers image segmentation techniques and their applications. The book includes object detection and classification applications and provides an overall background to statistical analysis in biomedical systems. The role of Machine Learning, including Neural Networks, Deep Learning, and the implications of the expansion of artificial intelligence is also covered. With contributions from prominent researchers worldwide, this book provides up-to-date and comprehensive coverage of AI applications in image processing where readers will find the latest information with clear examples and illustrations.

This book coherently presents advances in design principles, processes, and methods in healthcare product design. It captures the implications of technological advances on designing healthcare products especially when market and societal needs pull each other in opposite directions. The contents focus on innovative design thinking processes and methods in developing healthcare products, applications of digital technologies in healthcare product design, amalgamation of artificial intelligence and design thinking for healthcare product design and quality, sustainability, and regulatory aspects in the design process. This book is a useful reference for those in the industry and academia.

Taxonomien sind Modelle, um unübersichtliche Domänen zu analysieren, Komplexität zu reduzieren sowie Unterschiede und Ähnlichkeiten von Objekten zu erkennen. Ferner helfen sie, Wissen zu ordnen und so Wissen zu vergrößern. Da täglich neues Wissen entsteht, ist eine nutzungsorientierte Entwicklung von Taxonomien für die Wissenschaft und die Praxis von fundamentaler Bedeutung. Taxonomien sind unerlässlich für die Erforschung, Beschreibung und Strukturierung von Domänen. Trotz ihrer besonderen Bedeutung gibt es für viele Wissenschaften nur wenige Handlungsanleitungen zur Entwicklung von Taxonomien.In diesem Buch werden die Forschungsergebnisse der Dissertation mit dem Titel ¿Entwicklung einer Taxonomie für Patientenportale für Health Information Manager¿ präsentiert. Aufgrund der detaillierten Darstellung der Entwicklungsschritte und der eingesetzten Methoden kann diese Dissertationsforschung als Anleitung zur Entwicklung von Taxonomien dienen. Dabei ist die Evaluierung für die Nützlichkeit einer Taxonomie maßgeblich. Mit dem ¿TED Taxonomy-Evaluation-Delphi Approach¿ entwickelte der Autor eine neue Methode zur Evaluierung von Taxonomien, welche hier ausführlich beschrieben wird.

This book presents a systematic overview of the technologies currently being explored and utilized in the fields of cardiovascular tissue engineering and regenerative medicine. Considering the unprecedented rapid progress occurring on multiple technological fronts in cardiac tissue engineering, this important new volume fills a need for an up-to-date, comprehensive text on emerging advanced biological and engineering tools. The book is an important resource for anyone looking to understand the emerging topics that have the potential to substantially influence the future of the field. Coverage includes iPS stem cell technologies, nanotechnologies and nanomedicine, advanced biomanufacturing, 3D culture systems, 3D organoid systems, genetic approaches to cardiovascular tissue engineering, and organ on a chip. This book will be a valuable guide for research scientists, students, and clinical researchers in the fields of cardiovascular biology, medicine, and bioengineering, as well as industry-based practitioners working in biomaterial science, nanomaterials and technology, and rapid prototyping and biomanufacturing (3D bioprinting). 

This book provides a comprehensive overview of the latest advances in a wide range of biomaterials for the development of smart and advanced functional materials. It discusses the fundamentals of bio-interfacial interactions and the surface engineering of emerging biomaterials like metals and alloys, polymers, ceramics, and composites/nanocomposites. In turn, the book addresses the latest techniques and approaches to engineering material surfaces/interfaces in, e.g., implants, tissue engineering, drug delivery, antifouling, and dentistry. Lastly, it summarizes various challenges in the design and development of novel biomaterials. Given its scope, it offers a valuable source of information for students, academics, physicians and particularly researchers from diverse disciplines such as material science and engineering, polymer engineering, biotechnology, bioengineering, chemistry, chemical engineering, nanotechnology, and biomedical engineering for various commercial and scientific applications.

pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment. pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.

Essentials of Ultrasound Imaging is an introduction to all aspects of acquiring and measuring pulse-echo data to form images. The book provides in-depth exploration of key physical processes, including wave propagation and interaction with physical media, piezoelectric transducers, arrays, and beam formation, and concludes with a survey of advanced topics in ultrasound. Uniquely, principles are revealed by examples from software simulation programs designed to demonstrate ultrasound concepts, and image and signal processing. There are also numerous examples from a Verasonics Vantage Research Ultrasound System to provide unparalleled insight into each step of ultrasound image creation, including signal processing, transducer operation, different types of beamforming, and image formation. The content is organized around a central functional block diagram which is, in turn, related to physical processes and processing involved in clinical and research imaging systems. With a thorough grounding in the fundamentals of physics and methods of ultrasound imaging, readers can better appreciate the introduction of advanced topics and various applications of ultrasound.

This book, written by the foremost international researchers and practitioners of genetic programming (GP), explores the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. In this year's edition, the topics covered include many of the most important issues and research questions in the ¿eld, such as opportune application domains for GP-based methods, game playing and co-evolutionary search, symbolic regression and ef¿cient learning strategies, encodings and representations for GP, schema theorems, and new selection mechanisms. The book includes several chapters on best practices and lessons learned from hands-on experience. Readers will discover large-scale, real-world applications of GP to a variety of problem domains via in-depth presentations of the latest and most significant results.

The book provides a thorough overview of recent developments in the design of AI systems and their uses in a range of industries, including education, technology, and bioinformatics. The papers in the proceedings were presented at the Sixth International Conference on Artificial Intelligence, Medical Engineering, and Education (AIMEE2022), which took place in Wuhan, China, from August 19 to 21, 2022.The book underlines the need for the intensification of training of an increasing number of appropriate specialists given the rapid growth of AI systems. In order to replicate human and other species' natural intelligence in digital AI systems, the researchers have been studying genetics and inherited biological processes in-depth. These studies offer fresh ideas for developing ever more powerful AI techniques. The featured articles cover a variety of themes in the fields of mathematics and biomathematics, medical approaches, technical and educational approaches, and medical approaches. The book is a compilation of recent academic papers in the discipline, covering a wide range of topics that are important to both business managers and engineers. This proceedings is a fantastic resource for asset management practitioners, researchers, and academics, as well as undergraduate and graduate students who are interested in AI, bioinformatics systems, and their developing applications. This is due to the breadth and depth of the proceedings. Experts, students, and other people who are interested in learning about how AI systems might be used in the future are the target audience.

This book covers key topics in the emerging field of plasmonic MEMS, with an emphasis on practical aspects. Although readers can find many comprehensive textbooks on electromagnetic waves, nanophotonics and plasmonics, most of these lack the focus needed for a thorough grasp of plasmonic micromachining and MEMS.This book introduces the main framework of plasmonic MEMS, providing an overview of introductory concepts, a thorough description of the basic foundations, along with the state-of-the-art and existing challenges. The author presents an abbreviated overview of the basic physics and devices related to electromagnetic waves and surface plasmons. Additional coverage includes recent advances in the fabrication of sub-100-nm patterns on micro scale devices and structures and a review of emerging techniques in the fabrication of plasmonic systems. A comprehensive and historical review of the current advances in the area of plasmonic nanofabrication is also included.This book focuses on an appealing and distinctive aspect of plasmonics, as a tool for patterning and the fabrication of ultra-fine resolution structures. The author reviews the recent developments in plasmonic MEMS and microsystems for biosensing applications, including refractive-index based label-free biosensing, plasmonic integrated lab-on-chip systems, plasmonic for near-field scanning optical microscopy (NSOM) and plasmonics on-chip system for cellular imaging.

Functional Nanocomposite Hydrogels: Synthesis, Characterization, and Biomedical Applications reviews how the unique properties of nanoscale composite materials make them ideal candidates for use in biomedical hydrogels. The book covers a range of key nanocomposite materials for use in biomedical hydrogels, including graphene quantum dot, cellulose and collagen nanocomposites. A wide selection of biomedical applications for functional nanocomposite hydrogels is explored, from drug delivery and cancer therapy, to wound healing and bioimaging. This is a key reference for those working in the fields of biomaterials, nanotechnology, pharmacology, biomedical engineering, and anyone with a particular interest in composites and hydrogels. To improve the properties of conventional hydrogels, nanoparticles or nanostructures are incorporated into the hydrogel networks, forming a composite hydrogel with specialized functional properties which are tailored to a specific biomedical application.

Dieses Buch befasst sich mit den Herausforderungen und Möglichkeiten von Open-Source- und kollaborativen Designansätzen und -strategien im biomedizinischen Bereich. Es bietet eine umfassende Reihe von bewährten Verfahren und Methoden, damit diese sicheren, innovativen und zertifizierbaren biomedizinischen Geräte die Patienten erreichen und erfolgreiche Lösungen für Probleme im Gesundheitswesen bieten. Die Kapitel sind so gegliedert, dass sie den gesamten Lebenszyklus von Open-Source-Medizintechnologien verfolgen. Die bereitgestellten Informationen sind äußerst praxisorientiert, da sie sich auf reale Studienfälle stützen, bei denen sich die Zusammenarbeit zwischen medizinischen Fachkräften, Ingenieuren und Technikern, Patienten und Patientenverbänden, politischen Entscheidungsträgern, Regulierungsbehörden und Bürgern als vorteilhaft erwiesen hat. Das Buch wird auch durch eine Online-Infrastruktur, UBORA, unterstützt, über die Open-Source-Medizinprodukte gemeinsam entwickelt und geteilt werden können, um die Medizintechnik zu demokratisieren und eine zugängliche biomedizintechnische Ausbildung zu fördern.

The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.