Neurovidenskab

The second edition of The Lateralized Brain: The Neuroscience and Evolution of Hemispheric Asymmetries provides for readers a volume detailing the functional and structural differences between the left and right hemispheres of the brain, highlighting how the widespread use of modern neuroimaging techniques such as fMRI and DTI have completely changed the way hemispheric asymmetries are currently investigated. In this new edition, all chapters have been updated with recent advances in the field, and a new chapter on hemispheric asymmetries in development and aging has been integrated. Also featured is a new, larger section on laterality in social behavior, alongside a comprehensive overview about key topics in laterality research, including its history, evolutionary perspectives, brain structure, and the role of the corpus callosum. Chapters cover functional hemispheric asymmetries in language processing, motor behavior, spatial attention, self- and face-perception, emotion processing, and social behavior. Additional topics include the ontogenesis of hemispheric asymmetries and their development over the life span, as well as sex differences and associations with clinical syndromes. This volume can be used by anyone working on hemispheric biology or in courses on hemispheric asymmetries.

HIV-Associated Neurocognitive Disorders (HAND) presents a complex and evolving challenge in the context of HIV-1 infection and treatment. This comprehensive volume dives into the clinical manifestations, molecular and cellular mechanisms, and therapeutic strategies underlying HAND and its associated comorbidities. This book brings together cutting-edge research and clinical insights, making it an essential resource for researchers, clinicians, and students engaged in HIV-related studies and neurocognitive research. This resource also aims to advance our understanding of HAND to contribute to the development of novel diagnostic tools and therapeutic interventions for improved patient outcomes.

Paraneoplastic Neurological Disorders, Volume 200 covers new, recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. Besides investigating the pathogenetic mechanisms of these disorders, this book also explores what the introduction of new drugs used in immune checkpoint inhibitor cancer therapy are teaching us in terms of immunopathogenesis. Following sections present individual syndromes (phenotypical clinical manifestations) of the CNS, PNS, NMJ, and muscle. Finally, the book investigates the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Side effects of the new immuno-oncological drugs increasingly used in cancer therapy are also covered.

FOOD ACCORDING TO YOUR BLOOD GROUP.BLOOD GROUP "AB DIABETIC" - THE ENIGMA.What you will learn in the following pages will change your life and that of your loved ones forever and in such a precise and safe way that in a few weeks they will feel the changes in their body in such a radical and different way, that They will feel and will be younger, stronger, more vigorous, full of energy, vitality and most importantly ... Full of great health and that when any viral or bacterial disease wants to enter their body, they will hardly feel a breakdown since their immune system and "ALKALINITY" (I will teach you later) - it will be so strong that it will be almost impossible for them to ever get sick again (this if they keep their new culture of feeding and living that I will teach them for life) and therefore lead them to live the average 100-year-old.

There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This book aims to meet the needs making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of this book targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy.

You can't tell how deep a puddle is until you step in it. When I am asked about my profession, I have two ways of answering. If I want a short discussion, I say that I am a mathematician; if I want a long discussion, I say that I try to understand how the human brain works. A long discussion often leads to further questions: What does it mean to understand "e;how the brain works"e;? Does it help to be trained in mathematics when you try to understand the brain, and what kind of mathematics can help? What makes a mathematician turn into a neuroscientist? This may lead into a metascientific discussion which I do not like par- ticularly because it is usually too far off the ground. In this book I take quite a different approach. I just start explaining how I think the brain works. In the course of this explanation my answers to the above questions will become clear to the reader, and he will perhaps learn some facts about the brain and get some insight into the construc- tions of artificial intelligence.

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature's longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 16th volume of a continuing series.Chapter "e;Epithelial Stem Cells: Making, Shaping and Breaking the Niche"e; is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Unravel the Secrets of Your Mind: A Journey into Cognitive BiasesStep into the intriguing world of cognitive biases with this comprehensive guide that promises to transform the way you perceive yourself and others. Packed with fascinating insights, this book unveils the subtle but powerful ways our minds shape our understanding of reality.In The Biased Brain, you will delve deep into the heart of human cognition and discover hundreds of cognitive biases that influence our decisions. Written by an expert in the field, this book is a powerful tool that will enable you to navigate your life with enhanced understanding and control.Nearly 500 pages packed with well-researched, engaging content that will draw you into the labyrinth of the human mind. You will explore concepts that will make you question your assumptions and provoke you to think critically about your thought processes. This book doesn't just offer theoretical knowledge; it also provides practical solutions to identify and overcome your biases.It doesn't matter whether you're a student of psychology, a curious observer of human behavior, or someone who's simply looking to better understand their own mind-this book has something for everyone. In fact, it might just be the most insightful book you will read this year.Are you ready to challenge your perceptions and unveil the biases hiding in plain sight? This book is your map to understanding the complex landscape of human cognition. So, why wait? Start your journey now and transform the way you see yourself and the world.Grab your copy of The Biased Brain today and embark on an enlightening journey into the human mind.

This volume discusses the latest techniques used in the diverse fields of single cell 'omics and covers topics such as quantifying the single cell transcriptome; isolation of cells in nanoliter volumes for single cell proteomics measurements by nano-LC-MS/MS; and single cell protein characterization by immunoblotting. A wide range of methodologies are highlighted, ranging from high-yield chemical amplification to mass spectrometry and nanotechnology for the analysis of the chemical constituents of cells. In the Neuromethods series style, chapters include both in-depth overviews, as well as detailed protocols that provide the key advice from specialists you need to get successful results in your laboratory. Cutting-edge and comprehensive, Single Cell 'Omics of Neuronal Cells is a valuable resource for experienced and novice researchers interested in learning more about this field and its future developments.

Written by over seventy scientists and clinicians worldwide from China, USA, Germany, Canada, Japan and other countries, this monograph, with nearly 450 figures and tables, covers a wide range of advanced progress in acupuncture research, from experimental research to clinical applications. In addition to exploring the histopathological basis for acupuncture and mathematical simulation of acupoint response to stimulation, initiation and transduction of acupuncture signals and cellular mechanisms during acupuncture effects as well as chemical and physical characteristics of moxibustion on acupoints are broadly discussed. The topics also include novel data on acupuncture effect with advanced imaging techniques, a unique understanding of meridian-viscera correlation, specific interactions between meridians and neurosensory organs within the system of homeostatic regulation and the acupuncture-induced influences on autonomic function. Several chapters introduce specific approaches with dry needling, silver needling and stainless needling for certain diseases, such as myofascitis, supportive care for breast cancer and chemotherapy-induced peripheral neuropathy as well as perioperative care of surgical patients. Moreover, this book discusses recent research on acupuncture therapy and potential mechanisms for a number of severe and refractory neurological disorders, including hyperactivity of hypothalamic-pituitary-adrenal axis, orofacial pain, chronic pain, itch, multiple sclerosis, autism spectrum disorders, cerebral palsy, depressive disorders, Alzheimer's disease and ischemic brain injury. The vast amount of information offered in this book provides a comprehensive perspective on advanced acupuncture research to not only acupuncturists, but also to neuroscientists, neurologists, and other clinicians. For medical students and graduate and undergraduate students majoring in biology, physiology and neuroscience, this book offers an advanced course in learning about the mechanism-driven advances in alternative and complementary medicine.

This book presents an interdisciplinary approach to the study of affectivity and human learning by bridging the gap between neuroscience, cultural and cognitive psychology. It brings together studies that go beyond the focus on cognitive-intellectual variables involved in learning processes and incorporate the study of the role played by affectivity and emotions in learning not only at educational settings but in all processes of transformation and human development, thus presenting affectivity as a catalyst and mediator of all daily learning processes.Chapters brought together in this contributed volume present both theoretical contributions and results of empirical research from different disciplines, such as neuroscience, cognitive psychology, cultural psychology, educational psychology, developmental psychology and philosophy, and are grouped into five thematic sections. The first part of the book brings together chapters discussing different aspects of the role played byaffectivity in learning processes from the perspectives of cultural, educational and developmental psychology. The second part is dedicated to the role of affectivity for teachers during their training as educators and during their pedagogical practice in diverse contexts. The third part focuses on the relationship between affectivity and learning from a neuroscientific point of view. The fourth part discusses affectivity and learning in therapeutic and clinical contexts. Finally, the fifth part brings together chapters about affectivity and learning in everyday life.By bringing together this rich interdisciplinary collection of studies, Affectivity and Learning: Bridging the Gap Between Neurosciences, Cultural and Cognitive Psychology will be a valuable resource for researchers in the fields of psychology, neuroscience and education, as well as for educators and teachers interested in knowing more about the relationship between affectivity and human learning.

This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions.  The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches. 

This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson¿s, and Alzheimer¿s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.

"Using new empirical evidence, this book weaves together insights from a multidisciplinary review into a comprehensive theory on perspective taking. It is written for anyone interested in the phenomenon of perspective taking, including psychologists, literary scholars, linguists, philosophers, and educators"--

This book contains the proceedings of the XVIII International Symposium on Retinal Degeneration (RD2018). A majority of those who spoke and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium focused on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the ¿best¿ and ¿most important¿ meetings in the field.The volume presents representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. While advances in these areas of retinal degenerations were described, there will be many new topics that either are in their infancy or did not exist at the time of the last RD Symposium. These include the role of inflammation and immunity, as well as other basic mechanisms, in age-related macular degeneration, several new aspects of gene therapy, and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that withsuccessful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those were reported at the RD2016 meeting and included in the current volume. We anticipate the excitement of those working in the field and those afflicted with retinal degenerations is reflected in the volume.

Louis Berman wrote a book titled "The Glands Governing Personality". The book examines the link between internal secretion glands and personality in humans. According to Berman, the thyroid, adrenal, pituitary, and reproductive glands all play a significant part in defining a person's physical and mental make-up. In what he refers to as "endocrine kinds," Berman categorizes human nature into four main categories. The proportional activity of the body's various glands determines these categories. Each kind, according to Berman, has unique physical and psychological qualities, such as variations in energy levels, temperament, and personality traits. The impact of these glands on a variety of physical and mental health conditions, including as obesity, depression, and anxiety, is also covered in the book. According to Berman, better therapies for these illnesses may be created using knowledge of the endocrine system's function in personality. In terms of endocrinology and psychology, "The Glands Controlling Personality" is a groundbreaking piece of study. The book continues to provide a significant addition to our knowledge of the intricate interaction between the body and the mind, even if some of Berman's concepts may be out of date.

The brain has untold potential - Discover how it really works so you can make it optimize its performance.

This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes.The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios.At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy.  The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.

The story is about a adult female with degenerative disc disease and suffered an on duty injury requiring surgery. The surgery was to implant an orthopedic device which caused a severe allergic reaction. The female suffered immensely well doctors didn't know what to do. Female went into a very dark place before fighting for her life and investigating why she was so sick. None of the doctors could figure it out. If female had not done thorough investigation and documentation she would've never been able to overcome the situation. The doctors learned from this female as did other patients. My name is Jenny Stetson I was born and raised in Santa Maria, California, where I grew up, however, my parents to travel across United States and back. I have lived in many states across the United States. I love the ocean I love swimming, gardening, reading, books, and spending time with my family I am a retired, Deputy Sheriff Coroner I personally experienced the degenerative disc, orthopedic surgeries, metal, allergies, neuropathy, etc. it brought me to a very dark place in my life where I learned a lot about my strength, and the power of God. I learned to meditate to control the pain and anxiety. My perseverance and tenacity got me out of the dark hole. Researched and found scientific proof. I chose to write this book to help others potentially going down that same road so they don't have to suffer like I did.

This book will make you a perfume insider. Discover the effects, trends and future of perfume. Perfumery is on the verge of its third revolution, neuroperfumery, due to new methods of brain research and current findings in fragrance psychology.With this exciting and well-written book, you will gain a comprehensive insight into the creation, world and practice of modern perfumery, as well as interesting insider information. Current findings in psychology, aromatherapy, brain research and neuroperfumery on the effects of fragrances make Beautiful SCENT a treasure trove of new insights. As a non-fiction book with an advice component, it is easy to read without prior knowledge and provides many practical tips. Among other things, you will learn that some perfumes can do much more than just smell good, how perfumers and marketers create their perfumes, which scent preferences prevail and how the effect of scent can specifically influence one's own experience and enjoyment of life. Target groupsAll those who love perfumes and fragrances and would like to learn more about the magical effect of perfumes on well-being and perhaps play with the idea of creating their own perfume one day. It is also ideal for those who work in the fragrance, cosmetics and beauty industry and would like to refresh their knowledge of perfumes. About the authorDr. Joachim Mensing is a qualified psychologist, sociologist and trained nose with over 30 years of professional experience in perfumery and fragrance therapy. At one of the largest fragrance manufacturers, he became a trend coach for perfumers and developed methods of perfume development and marketing. Many of the perfumes he worked on received coveted awardssuch as the Fifi Award, the Oscar for perfumes. He himself received the honorary award of the FRAGRANCE FOUNDATION for the development and marketing of the perfumes Cool Water by Davidoff, Joop! and Jil Sander, and he was also recognized for studies in neuroperfumery and neuropsychology.

This volume covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia using state-of-the-art microscopy techniques including super-resolution imaging, electron microscopy, and ultra-high field MRI. The chapters in this book cover topics such as analysis of neurodegeneration in the post-mortem characterization of preclinical animal models, in vivo modeling in cell death in different model systems and brain organoids, single cell clonal analysis using Mosaic Analysis with Double Markers in genetic mouse models, and genome and proteomic methods for analysis of mRNA dynamics and quantitation of targeted peptides. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Neuronal Cell Death: Methods and Protocols is a valuable resource for any scientist and researcher interested in learning more about this developing field.

Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological, and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.

Neuroplasticity is the change in neural pathways and synapses that occurs due to certain factors, like behavior, environment, or neural processes. Cognitive-behavioral therapy modified the neural circuits involved in the regulation of negative emotions and fear extinction in judged treatment responders. Neuroimaging studies revealed that cbt was able to change dysfunctions of the nervous system. Persons with anxiety disorders are characterized by excessive neural reactivity in the amygdala, which is normalized by effective treatment like cognitive behavior therapy (cbt). Here's what you can find inside:Discover how anyone can rewire his brain, and get a step-by-step guide to doing soGet beginner exercises for developing a powerful brainUnlearn bad habits and design your brain for successDevelop self-discipline, self-control and a burning motivation to accomplish your goalsAnd much, much more!Is it true what most people say, that you cannot teach old dogs new tricks? Is it almost impossible to learn new things as you grow older? Are you kicking yourself right now for not paying close attention at class when you were younger? Don't blame yourself too much for slacking off in your schoolwork, the truth is that you can still learn new things even if you are of an advanced age.

Sensitive periods occur when unique experiences permanently influence brain development either by their presence or absence. This volume covers underlying brain systems and behaviors that are sculpted by the environment in humans and animals in a search for commonalities. The mechanisms involved, the importance of timing in the process, and factors that can change the brain are discussed in this exciting book. Different chapters examine how experience guides the development of cells, circuits, and function using vision, cortical circuits, and cognition as frameworks. Scientific evidence for effective preventative intervention approaches, including diet, exercise, and music, are included to find ways to maximize child and adolescent development. The adverse effects of early brain injury are also included. As sensitive periods are gaining importance in their application in the real-world, novel statistical approaches for human studies are presented and the importance of sensitive periods are covered by examining the juvenile justice system. The book has interdisciplinary appeal and scholars with an interest in brain resiliency or vulnerability will find it of particular interest.

The Dictionary of Hallucinations, second edition, is an alphabetical listing of issues pertaining to hallucinations and other misperceptions. They can be roughly divided into four categories:1. Definitions of individual hallucinatory symptoms2. Medical conditions and substances associated with the mediation of hallucinations3. Historical figures who are known to have experienced hallucinations4. Miscellaneous issuesEach of the definitions of individual hallucinatory symptoms includes: a definition of the term its etymological origin the year of introduction (if known) a reference to the author or authors who introduced the term (if known) a description of the current use a brief explanation of theetiology and pathophysiology of the symptom at hand (if known) references to related terms references to the literatureThe second edition of A Dictionary of Hallucinations serves as a reference manual for neuroscientists, psychiatrists, psychiatric residents, psychologists, neurologists, historians of psychiatry, general practitioners, and academics dealing professionally with concepts of hallucinations and other sensory deceptions. This new edition provides updated information and references, and includes newly discovered hallucinations, bringing together contributions by other authorities within the field, with all the entries edited by Prof. Blom.Doody's Review: The book's purpose is to provide a collection of terms and related information for a variety of clinical and non-clinical applications, that can serve as a springboard for further inquiry about specific and lesser-known sensory phenomena. Not only does this book meet its objectives, but it fills a void in providing a comprehensive list of technical terms matched to otherwise hard-to-describe human experiences.