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Bioinformatik

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  • af Philip Ball
    121,95 - 215,95 kr.

  • af Kazuharu Arakawa
    1.105,95 - 1.758,95 kr.

    This volume provides comprehensive dry and wet experiments, methods, and applications on nanopore sequencing. Chapters guide readers through bioinformatic procedures, genome sequencing, analysis of repetitive regions, structural variations, rapid and on-site microbial identification, epidemiology, and transcriptome analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Nanopore Sequencing: Methods and Protocols aims to be comprehensive guide for researchers.

  • af Richard J. Simpson
    1.437,95 - 2.199,95 kr.

    This third volume provides comprehensive protocols on pre-analytical, analytical, plasma, and serum proteomics. New and updated chapters are divided into nine sections, detailing blood processing and handling strategies, discovery- and targeted-based mass spectrometry, including workflows to aid in discovery and targeted data analysis, in addition to software and bioinformatics for the plasma proteome. This edition further integrates emerging areas in the development of technologies for plasma proteomics and assay platforms in biomarker discovery and translational proteomics, enrichment and detection strategies to understand the plasma proteome, and peptide, lipid and metabolite targeted assays. We also detail the emerging analysis of extracellular vesicles isolated from plasma. Written in the format of the highly successful Methods in Molecular Biology series, each of the 33 chapters includes an introduction to the topic, lists necessary materials and methods, includes hints and tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Serum/Plasma Proteomics: Methods and Protocols, Third Edition aims to be comprehensive guide for researchers.

  • af Ivan Selesnick, Iyad Obeid & Joseph Picone
    987,95 - 1.065,95 kr.

  • af Bernhard Haubold & Angelika Börsch-Haubold
    715,95 - 773,95 kr.

  • af Kamarul Arifin Ahmad
    1.924,95 kr.

    This book gives a complete overview of current developments in the implementation of high performance computing (HPC) in various biomimetic technologies. The book presents various topics that are subdivided into the following parts: A) biomimetic models and mechanics; B) locomotion and computational methods; C) distributed computing and its evolution; D) distributed and parallel computing architecture; E) high performance computing and biomimetics; F) big data, management, and visualization; and G) future of high performance computing in biomimetics. This book presents diverse computational technologies to model and replicate biologically inspired design for the purpose of solving complex human problems. The content of this book is presented in a simple and lucid style which can also be used by professionals, non-professionals, scientists, and students who are interested in the research area of high performance computing applications in the development of biomimetics technologies.

  • af Pedro H. Oliveira
    1.362,95 - 1.758,95 kr.

    This volume details state-of-the-art computational methods designed to manage, analyze, and generally leverage epigenomic and epitranscriptomic data. Chapters guide readers through fine-mapping and quantification of modifications, visual analytics, imputation methods, supervised analysis, and integrative approaches for single-cell data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Computational Epigenomics and Epitranscriptomics aims to provide an overview of epiomic protocols, making it easier for researchers to extract impactful biological insight from their data.

  • af Wesley A. C. Godoy
    1.560,95 kr.

    This book combines chapters emphasising mathematical, statistical, and computational modelling applied to insect populations, particularly pests or natural enemies in agricultural landscapes. There is a gap between agricultural pest experimentation and ecological theory, which requires a connection to supply models with laboratory, and field estimates and projects receiving inputs and insights from models. In addition, decision-making in entomology with respect to pest management and biological conservation of natural enemies has been supported by results obtained from different computational and mathematical approaches. This book brings contemporary issues related to optimization in spatially structured landscapes, insect movement, stability analysis, game theory, machine learning, computer vision, Bayesian modelling, as well as other frameworks.

  • af Wilson R. Spironello
    1.390,95 kr.

    The mammal fauna of the Brazilian Amazon is one of the most diverse on Earth with over 450 known species. Bringing together more than 70 of the world¿s top experts on Amazonian mammals, this book unites, for the first time, up-to-date data on the current state of knowledge on the ecology of all groups of non-rodent mammals in the Brazilian Amazon, analyses the effectiveness of current conservation programmes and identifies research and conservation priorities for the future.

  • af Makoto Sato
    452,95 - 600,95 kr.

    This book helps the reader make use of the mathematical models of biological phenomena starting from the basics of programming and computer simulation. Computer simulations based on a mathematical model enable us to find a novel biological mechanism and predict an unknown biological phenomenon. Mathematical biology could further expand the progress of modern life sciences. Although many biologists are interested in mathematical biology, they do not have experience in mathematics and computer science. An educational course that combines biology, mathematics, and computer science is very rare to date. Published books for mathematical biology usually explain the theories of established mathematical models, but they do not provide a practical explanation for how to solve the differential equations included in the models, or to establish such a model that fits with a phenomenon of interest. MATLAB is an ideal programming platform for the beginners of computer science. This book starts from the very basics about how to write a programming code for MATLAB (or Octave), explains how to solve ordinary and partial differential equations, and how to apply mathematical models to various biological phenomena such as diabetes, infectious diseases, and heartbeats. Some of them are original models, newly developed for this book. Because MATLAB codes are embedded and explained throughout the book, it will be easy to catch up with the text. In the final chapter, the book focuses on the mathematical model of the proneural wave, a phenomenon that guarantees the sequential differentiation of neurons in the brain. This model was published as a paper from the author¿s lab (Sato et al., PNAS 113, E5153, 2016), and was intensively explained in the book chapter ¿Notch Signaling in Embryology and Cancer¿, published by Springer in 2020. This book provides the reader who has a biological background with invaluable opportunities to learn and practice mathematical biology.

  • af Daniel Zelterman
    746,95 - 877,95 kr.

  • af Ryusuke Sawada
    1.134,95 kr.

    This book aims to understand biological evolution through a physical approach, focusing on the macroscopic aspects of the biological genome. Readers will discover the connection between genomic information and the harmony of biological systems, a relationship that remains elusive to many researchers in biological sciences.The most common approach to understanding living organisms with physics is to begin with a single molecule of an organism. In contrast to this bottom-up approach, building from each molecule to the whole, this book takes a coarse-grained approach at the amino acid level to physically understand the macroscopic aspects of the organism. The book presents a system developed by the authors to predict membrane proteins with high accuracy using only physical parameters. Another distinctive perspective of this book is that it proposes the idea of a physical mechanism, other than natural selection, that orchestrates the emergence of order from random processes.The study of macroscopic aspects of living organisms based on this concept has parallels with thermostatistical mechanics for states of matter. Just as random processes create order in matter, there are physical random processes that form order in living organisms. This analogy is the central theme of the book.Using terms and analogies familiar to physicists, the book bridges the gap between biological and physical sciences. The book focuses on simple principles and is aimed primarily at researchers. While the content of this book is at the boundary area of biophysics, soft matter physics and bioinformatics, it will also be of interest to researchers and graduate students working on any biological topics.

  • af Anirban Bandyopadhyay
    1.924,95 kr.

    This book discusses various aspects of bioinspired technologies but with an additional emphasis on the medical science, starting from the popular article on neurobiology to pure biophysics that ends with the superintelligence of biological systems that could be reverse engineered. It covers eight different aspects of natural intelligence, starting from the fundamental electromagnetic properties of a protein to the vibrations and the resonance of the entire biomaterial system. It also covers a wide spectrum of hierarchical communication among different biological systems for intelligence and then medical science is applied.

  • af Geir Halnes
    522,95 - 1.404,95 kr.

  • af Maria Pietronilla Penna
    1.475,95 kr.

    This book presents the proceedings of the Eighth National Conference of the Italian Systems Society. The contributions underline the need for Systemics and Systems Science in order to address multiple, changing systems involving several coherent versions.The conference focused on identifying, discussing, and understanding possible interrelationships between fundamental theoretical advances in different disciplines. Given their scope, these proceedings represent a valuable asset for all researchers whose work involves multiple systems.

  • af Mayuko Nakamaru
    1.097,95 - 1.174,95 kr.

    This book shows that evolutionary game theory can unravel how mutual cooperation, trust, and credit in a group emerge in organizations and institutions. Some organizations and institutions, such as insurance unions, credit unions, and banks, originated from very simple mutual-aid groups. Members in these early-stage mutual-aid groups help each other, making rules to promote cooperation, and suppressing free riders. Then, they come to ¿trust¿ not only each other but also the group they belong to, itself. The division of labor occurs when the society comes to have diversity and complexity in a larger group, and the division of labor also requires mutual cooperation and trust among different social roles. In a larger group, people cannot directly interact with each other, and the reputation of  unknown people helps other decide who is a trustworthy person. However, if gossip spreads untruths about a reputation, trust and cooperation are destroyed. Therefore, how to suppress untrue gossip is also important for trust and cooperation in a larger group. If trustworthiness and credibility can be established, these groups are successfully sustainable. Some develop and evolve and then mature into larger organizations and institutions. Finally, these organizations and institutions become what they are now. Therefore, not only cooperation but also trust and credit are keys to understanding these organizations and institutions.The evolution of cooperation, a topic of research in evolutionary ecology and evolutionary game theory, can be applied to understanding how to make institutions and organizations sustainable, trustworthy, and credible. It provides us with the idea that evolutionary game theory is a good mathematical tool to analyze trust and credit. This kind of research can be applied to current hot topics such as microfinance and the sustainable use of ecosystems.

  • af Houneida Sakly
    856,95 - 1.317,95 kr.

  • af Günther Palm
    1.207,95 - 1.360,95 kr.

  • af Mitsuru Matsumoto
    1.924,95 kr.

    This book overviews ongoing and upcoming clinical applications of basic immunology. Recent advances in our knowledge of immunology coupled with new technologies have aided in the development of efficient cancer immunotherapy, as well as the control of emerging microorganisms such as SARS-CoV-2. However, knowledge of basic immunology has not been fully utilized even after the discoveries of immune checkpoint inhibition for cancer immunotherapy and the development of mRNA vaccination against SARS-CoV-2. There is still room for improving the clinical application of basic immunology. The book summarizes the achievements in clinical applications of basic immunology and highlights what can be further extended to make immunology a more practical human science. Basic immunology and its clinical applications are two wheels of the same cart in the immunology field, which aids in the development of more efficient cancer immunotherapy and rapid control of infectious diseases against microorganisms, including new viruses and classical toxoplasmosis. The exploration of ongoing and upcoming applications of basic immunology in this book makes it a useful resource for immunologists, physicians, molecular and genome biologists, bioinformaticians, and students in these fields.

  • af Aditya Khamparia
    1.475,95 kr.

    This book offers information on intelligent and computational techniques for microbial data associated with plant microbes, human microbes etc. The main focus of this book is to provide an insight on building smart sustainable solutions for microbial technology using intelligent computational techniques.Microbes are ubiquitous in nature, and their interactions among each other are important for colonizing diverse habitats. The core idea of sustainable computing is to deploy algorithms, models, policies and protocols to improve energy efficiency and management of resources, enhancing ecological balance, biological sustenance and other services on societal contexts. Chapters in this book explore the conventional methods as well as the most recently recognized high-throughput technologies which are important for productive agroecosystems to feed the growing global population. This book is of interest to teachers, researchers, microbiologist, computer bioinformatics scientists,plant and environmental scientist, and those interested in environment stewardship around the world. The book also serves as an advanced textbook material for undergraduate and graduate students of computer science, biomedicine, agriculture, human science, forestry, ecology, soil science, and environmental sciences and policy makers.

  • af Felix Scholkmann
    2.583,95 - 2.727,95 kr.

  • af Lawrence Hunter
    1.941,95 kr.

    The Pacific Symposium on Biocomputing (PSB) 2024 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2024 will be held on January 3 - 7, 2024 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2024 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

  • af Jie Zhou
    1.248,95 kr.

    "This unique compendium provides state-of-the-art computational methodology and applications in bioimage informatics. It covers cutting-edge technology developments in biological image analysis, where images come from new modalities and are often large scale, high throughput and high dimensional. The book reflects advances in intelligent algorithms for tasks such as biological image segmentation, reconstruction, and object tracking. Contributed by world renowned researchers, this useful reference text presents case studies that can potentially help readers find approaches and resources to address their imminent scientific problems"--

  • af Zheng Rong Yang
    1.060,95 kr.

    Due to its capability of handling very complex problems and its high flexibility in adapting to different algorithms, the kernel machine plays a crucial role in machine learning.Bio-Kernel Machines and Applications will introduce a new type of kernel machine for the exploration and modeling between the genotypic inherent structures of short protein sequences or nucleic sequences and the phenotypic biological properties or functions of proteins or nucleotides.The book seeks to establish the fundamentals of the bio-kernel machines by presenting the basic principle and theory of the kernel machine and the various formats of kernel machines, such as string kernel machines adapted for biological applications. The book will also introduce several biological applications of the mutation matrices, demonstrating how mutation matrices can enhance the efficiency and biological relevance of machine learning models applied in specific biological problems.Through analyzing current applications of bio-kernel machines, readers will delve into the advantages of the bio-kernel machines and explore how bio-kernel machines can be further enhanced to tackle a wide spectrum of biological challenges and pave the way for future advancements.

  • af Anna Bernasconi
    520,95 kr.

    This book is a revised version of the PhD dissertation written by the author to receive her PhD from the Department of Electronics, Information and Bioengineering at Politecnico di Milano, Italy. The work deals with one of the central objectives of the European Research Council project ¿Data-Driven Genomic Computing¿, i.e., building an integrated repository for genomic data. It reflects the research adventure that starts from modeling biological data, goes through the challenges of integrating complex data and their describing metadata and finally builds tools for searching the data empowered by a semantic layer. The results of this thesis are part of a broad vision: the availability of conceptual models, related databases, and search systems for both humans and viruses genomics will provide important opportunities for research, especially if virus data will be connected to its host, the human being, who is the provider of genomic and phenotype information.In 2023, the PhD dissertation won the CAiSE PhD Award, granted to outstanding PhD theses in the field of information systems engineering.

  • af Clara Mihaela Ionescu
    1.219,95 kr.

    This book provides the most valuable and updated research on computational and mathematical models in biological systems from influential researchers around the world and contributes to the development of future research guidelines in this topic.Topics include (but are not limited to):modeling infectious and dynamic diseases;regulation of cell function;biological pattern formation;biological networks;tumor growth and angiogenesis;complex biological systems;Monte Carlo methods;Control theory, optimization and their applications

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