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The diseases of the central or peripheral nervous system are called neurological disorders. These disorders include epilepsy, Alzheimer's disease, and other dementias. Cerebrovascular diseases such as stroke, migraine, multiple sclerosis, Parkinson's disease, etc. are also considered as neurological diseases. A biomarker or biological marker is a cell, tissue, or body fluid cell that can be measured and evaluated to indicate a pharmacological response to a normal biological process, pathogenic process, or therapeutic intervention. Biomarkers characterize the progression of the disease from the earliest natural signs of the disease. Biomarkers assess the disease susceptibility and severity enabling prediction of outcomes, deciding interventions, and assessing the therapeutic responses. Based on clinical applications, biomarkers can be categorized as molecular biomarkers, cellular biomarkers, or imaging biomarkers. This book aims to shed light on some of the unexplored aspects of biomarkers. It presents researches and studies performed by experts across the globe on the topic in detail. It attempts to assist those with a goal of furthering their studies in the field of biomarkers and biomarker development.
Neurological diseases are disorders of the nervous system that affect the functioning of the brain and the nerves found throughout the human body and the spinal cord. The most common neurological disorders are epilepsy, Alzheimer's disease, migraine, stroke, Parkinson's disease, multiple sclerosis and cerebral palsy. The term biomarker or biological marker refers to a biological molecule found in blood, tissues or other body fluids, which indicates a normal or abnormal process, a condition, or a disease. Biomarkers help to diagnose a disease or condition, or to detect the disease progression, and record the effect of new drugs and therapeutic strategies as they are generated. Neurological biomarkers are used to diagnose a variety of neurological disorders and to monitor the advancement of these diseases or effect of the treatment. This process aids in predicting outcomes, determining interventions, and evaluating the therapeutic responses. This book is compiled in such a manner, that it will provide an in-depth knowledge about neurological biomarkers. It is a vital tool for all researching or studying the biomarkers of neurological diseases.
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