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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials - Meinhard Kieser - Bog

Bag om Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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  • Sprog:
  • Engelsk
  • ISBN:
  • 9783030495275
  • Indbinding:
  • Hardback
  • Sideantal:
  • 396
  • Udgivet:
  • 20. november 2020
  • Udgave:
  • 12020
  • Størrelse:
  • 241x162x32 mm.
  • Vægt:
  • 756 g.
  • 8-11 hverdage.
  • 29. januar 2025
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Beskrivelse af Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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