Bøger i Advances in Experimental Medicine and Biology serien

This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses.

RNAs form complexes with proteins and other RNAs. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA-based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways.

This volume provides a representative survey of the current science of brain repair. It offers a broad introduction into molecular imaging, stem cell biology, cell therapy, animal models, central nervous system malignancies, stroke, and neurodegeneration.

Providing information on cystic fibrosis, this work is of interest to molecular biologists, physiologists, scientists working in pharmaceutical research and drug development, physicians and researchers in cystic fibrosis and related diseases.

The American Peptide Society (APS) provides a forum for advancing and promoting knowledge of the chemistry and biology of peptides.

This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.

The aim of this book is to present a unique compilation of lectures given by international speakers at the Hammersmith Hospital during the recent Meetings in Hepato-Pancreato-Biliary and Transplantation.

This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms.

Cell surface molecules are critically important in regulating cell structure and function.

In collaboration with the Breast Cancer Research Foundation (BCRF), this timely volume provides a comprehensive review on all areas of breast cancer survivorship research, highlighting research that is underway or in development.

This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

Consumer understanding of the concept of early nutrition programming and the extent to which early nutrition programming is taken into account in infant feeding policies are also discussed.

This book discusses the different regulatory pathways for gene therapy (GT) and cell therapy (CT) medicinal products implemented by national and international bodies throughout the world (e.g.

This ground-breaking book brings together researchers from a wide range of disciplines to discuss the control and coordination of processes involved in perceptually guided actions.

This book is a blend of medical research and clinical practice. Hopefully, it will be a source of information on interdisciplinary medical research advancements, addressing the needs of medical professionals, from scientists to clinicians and allied health professionals.

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health.

Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come.This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction.

Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies.

Pulmonary disorders significantly contribute to the current level of disease burden. This book highlights the issues involved with diagnosing and managing various pulmonary conditions such as chronic obstructive pulmonary disorders, respiratory tract infections, including those developing as a sequel of antibiotic treatment, and others.

The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures.

The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis and explaining the basic cell biological mechanism.

The book presents the latest advances in research into health effects of air pollution, with heavy motor vehicle traffic or cigarette smoke as the exemplar of pollution.

This book will focus on the differentiation and regulation of subsets of CD4+ T cells. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.

Cardiorespiratory function is prominently affected by oxidative stress. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented.

The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation.

A host of neurotransmitters and neuroactive substances underlies respiratory regulation in health and disease. It is now clear that a complex interaction among various neuroactive substances, rather than a single one, forms the basis of respiratory changes.

This volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. The chapters cover vaccination strategies in various age-groups of people and provide the extensive amount of knowledge on the immune response to influenza vaccination in a spectrum of disease conditions.

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales.

Asthma is a chronic relapsing airways disease that represents a major public health problemworldwide.