Bøger i Basic and Clinical Aspects of Neuroscience serien

The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.

Gene expression converts the information coded by our genesinto proteins. This volume presents a didacticapproach to the understanding of the basic processes of geneexpression and their involvement in certain brain diseases,such asAlzheimer's disease and schizophrenia.

This volume deals with the known aspects of somatostatin, one of the oldest phylogenetic hormones, which is a regulatory peptide with remarkable characteristics. It is a non-classical neurotransmitter in both the central nervous sytem and in the gastroenteropancreatic system.

It goes on to show how neuroendocrine investigations may give insights into the functioning of neurotransmitter sys tems at least in the hypothalamus, to end with a chapter which assesses very critically the errors and deficiencies of the concepts and techniques used in the attempt to understand the functioning of the brain and the mind.

Cell transplantation to the brain and spinal cord is awell-established research tool for studies on cellular andmolecular mechanisms, but can it be developed into a usefultherapuetic approach in human neurological disorders?