Bøger i Developments in Applied Microb serien

Antimicrobial Dressings: The Wound Care Applications explores the literature surrounding the catalytic behavior of proteolytic enzymes immobilized together with nanoparticles. As numerous applications using proteolytic enzymes for debridement, silver as antibiotic and nanoparticles for enzyme immobilization were developed in the last years, this book explores interdisciplinary information combining nanotechnology, biotechnology and medicine and how it's still in early stages. The book adopts a holistic approach in a lifecycle context to evaluate their final feasibility, including industrial exploitability without disregard of the potential risks of enzymes and nanomaterials to human health and the environment.

Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.

Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration. Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy. Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

The Potential of Microbes for a Circular Economy provides an understanding of the role of microbes in a circular economy (CE). The book covers the development of effective bio-based formulations for field applications and describes the basic principles and applications, the important role of microorganisms, and new insights into a sustainable ecosystem for the circular economy. In addition, it compiles the latest advancement in the field of CE by covering microbes and microbial products, thus providing microbiologists the tools to engage with the public, policymakers, and industry to inform the debate on addressing current challenges.

Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes, including the secretion of metabolites which make them unique. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells, for products for direct use, or as starting raw materials in the manufacture of other commercial products. The book reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. Additional sections cover fundamental principles of established and innovative industrial microbiology and biotechnology processes and products while also discussing industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products.

Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices. The book's content further explains newly developed techniques for sequencing DNA, generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction, and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics and its application and techniques.

Techniques for Downstream process for Biologic Drugs and Vaccines provides comprehensive technologies involved in processing postharvest broth to separate the target biological therapeutic products of extracellular or intercellular aspects in nature - to its highest purification form, and to thus make it acceptable to end users. The technologies involved in the post-harvesting of fermented broth are explained in this comprehensive resource in a simplified manner with different case studies to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. As conceptual development of biotechnology has taken new shape and style with the integration of medical sciences, physical science, and engineering, and has thus begun the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process, this book covers the most important aspects.

Entrepreneurship with Microorganisms explains both the basic science and applications of microbiology and bio-resource technology, shining a special emphasis on its entrepreneurial applications. By focusing on basic principles, current research, and global trends, this comprehensive book provides a critical resource and serves as a complete one-stop source for undergraduate and graduates in microbiology, food, agricultural science, medical science, and industrial microbiology biotechnology. In addition, this book will be helpful in the creation of economic (commercial) value of the microorganism(s) based products and technologies as well as opportunities for new jobs at the global level.

Integrative Strategies for Bioremediation of Environmental Contaminants, Volume Two: Avenues to a Cleaner Society focuses on the exploitation of various biological treatment technologies and their use to treat toxic contaminants present in industrial effluent to restore contaminated sites. The book includes coverage of combined treatments of microbes for reuse of wastewater and contaminated soil to successfully achieve eco-restoration, environment protection and sustainable development. In 14 chapters, this reference compiles current and advanced biotechnologies as well as future directions for research. This is a valuable resource for researchers in microbiology, biotechnology, environmental engineering and environmental science, and all those who wish to broaden their knowledge in the field of applied microbiology to develop sustainable waste management.

New Insights, Trends and Challenges in the Development and Applications of Microbial Inoculants in Agriculture provides information about how to develop high-quality microbial inoculants (biofertilizers and biopesticides) for increasing crop yields and quality and reducing the economic, environmental and health costs of food production. The book's chapters discuss cutting-edge approaches and techniques to develop bioformulations as reliable, viable solutions for food production, including the importance of a legal framework to guarantee the quality and safety of these bio-products. Additionally, it provides information on the current limitations and future approaches to enhance microbial inoculant development for contributing to global food security. Interest in biofertilizers and the potential for their use in sustainable agriculture is increasing. However, many commercial bioproducts are low quality due to the lack of quality standards which causes a decrease in efficiency, high variability in the field, and loss of confidence from farmers.

Diagnosis and Analysis of COVID-19 using Artificial Intelligence and Machine Learning-Based Techniques offers new insights and demonstrates how machine learning (ML), artificial intelligence (AI), and (Internet of Things (IoT) can be used to diagnose and fight COVID-19 infection. Sections also discuss the challenges we face in using these technologies. Chapters cover pathogenesis, transmission, diagnosis, and treatment strategies for COVID-19, Artificial Intelligence and Machine Learning, and Blockchain /IoT Blockchain technology, examining how AI can be applied as a tool for detection and containment of the spread of COVID-19, and on the socioeconomic and educational post-pandemic impacts of the disease. This is a multidisciplinary resource for those engaged in researching COVID-19 and how emerging technologies are being used as tools for detection, transmission and treatment strategies.

Algae Materials: Applications Benefitting Health offers a comprehensive analysis of biosensors, algae materials for clinical applications, algae polymers, proteins and pigments, algae for food applications and packaging, blue economy, algae forming, cosmetics, and more. The book enlists the less explored areas of algal bioproducts, including how the application of genetic engineering is currently used to enhance bioproducts. Even though there are numerous reviews and scattered documents available, there are some recent fields yet to explore.

Emerging Technologies in Applied and Environmental Microbiology describes various problems and solutions that arise in applied and environmental microbiology using scientific technologies. The book summarizes the main omic-based methods currently used to characterize environmental microorganisms, as well as approaches to analyzing and interpreting the bio information generated by experimentally based studies. Sections explore the current understanding of bacterial signaling through examples of communication systems that include signaling in gram-positive and gram-negative bacteria, along with discussions on how microorganisms interact with each other, with other organisms, and with the environment. In addition, this comprehensive resource highlights the importance of various emerging technologies for cleaning up pollution in the environment caused by human activities. Final sections assess the potential application of several existing, applied and environmental microbiological techniques and introduces new and emerging technologies through applied aspects.

Advanced Microbial Technology for Sustainable Agriculture and Environment focuses on plant-microbe interactions in respect to bioremediation and plant growth promotion, providing insights on diverse approaches such as genomics, metagenomics, proteomics, bioinformatics and other high-throughput analyses of environmentally relevant microorganisms. The impact of frequent applications of potentially toxic chemicals (pesticides and fertilizers) and increased industrialization processes on microbial diversity emphasizes the potential threat to microbial biodiversity in ecosystems. This is an ideal resource on current trends and the future of PGPR developments with bioremediation potential. Moreover, it gives a deep understanding of the genetics of microbial biodegradation and different remediation mechanisms that help to re-establish the natural environment.

Phytoconstituents and Antifungals covers a wide range of specific information on various phytoconstituents, their antifungal mode and the diagnosis and management of fungal infections. The book offers encouragement and empowers readers to re-embrace their knowledge of phytoconstituents and their various antifungal activities against most opportunistic pathogenic fungi as fungal diseases cause an estimated 1.5+ million deaths annually and over one billion people suffer from severe fungal disease. In this complex scenario, it is now clear that global warming and accompanying climate changes have resulted in increased incidence of many fungal infections. On the basis of all these factors, concerns on the occurrence of a pandemic fungal origin in the near future have been raised. In this context, to stop forgetting and underestimating fungal diseases is mandatory.

Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines provides insights on how to bring sustainability into biologic drug production. The cumulative facts and figures within in the book are helpful to promoters in monitoring value chain transfer process of super quality biologics for better return in profits. In addition, this is a useful reference for students, researchers and scientists in biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries. Conceptual development of biotechnology has taken new avenues with the integration of medical sciences, physical science, and engineering, hence this is a timely source. The current global market for vaccines, especially COVID-19, is tremendous. Bivalent oral polio vaccine, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally and recombinant DNA technology and protein engineering are helpful in the production of quality bio-products.

Endophytic Association: What, Why, and How focuses on the endophytic association of plants, how they have originated inside the host, their importance, and how they are beneficial for the environment, as well as humans. The book discusses how using endophytic microbes in agricultural fields can be enriched without impacting environment negatively, and how they can be utilized for pharmaceutical purposes, including bioremediation. It includes advanced and up-to-date information, as well as future directions for young researchers and scientists who are working in the field of agriculture, pharmaceuticals, bio nanotechnology and bioremediation of environmental contaminants for environmental protection and sustainable development.

Synergistic Approaches for Bioremediation of Environmental Pollutants: Recent Advances and Challenges focuses on the exploitation of various biological treatment technologies and their use to treat toxic contaminants present in industrial effluent and in restoring contaminated sites, which lacks in a more comprehensive manner in existing titles on similar topics available on the global market. The book comprises advanced biotechnologies and updated information, along with sustainable waste management developments and future directions for researchers and scientists working in the field of microbiology.

Application of Biofilms in Applied Microbiology gives a complete overview on the structure, physiology and application of biofilms produced by microbes, along with their potential application in biotechnology. Sections cover new technologies for biofilm study, physiology of microorganisms in biofilms, bacterial biofilms, biofilm development, and fungal biofilms, summarizing various technologies available for biofilm study. Subsequent chapters describe biofilm developments with Bacillus subtillis, Escherichia coli, and Pseudomonas putida, along with several chapters on the study of microbial biofilm and their advantages and disadvantages in the area of environmental biotechnology. The book closes with a chapter on the rapid development of new sequencing technologies and the use of metagenomics, thus revealing the great diversity of microbial life and enabling the emergence of a new perspective on population dynamics.

Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes' biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.Endophytic Fungi: The Full Story of the Untapped Treasure highlights the bioprospecting and applied aspects of endophytic fungal communities from diverse hosts and discusses the practical applications of such endophytes in detail. It also reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of this book is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. The book addresses one of the most eminent issues in this field: how to translate the potential that endophytic fungi hold in stable practical application.

Nanotechnological Applications in Virology explores the use of nanoparticles-based technologies to fight against viruses, also discussing the use of nanoparticles in the preparation of nano masks and as sanitizing agents. The role of nanotechnology against HIV, Hepatitis, Influenza, Herpes, Ebola and Zika using rapid detection and diagnostic techniques is included, as is a brief description of SARS, MERS, the novel Coronavirus, and recent advancements in its treatment process. Other sections cover the formulation of novel nano-vaccines for the treatment and control of viral infections like HIV, Hepatitis and COVID-19. Included toxicological studies of nanoparticles provide readers with a brief overview on global scenarios regarding viral infections. Nanotechnology is the present age technology, with wide usage in different areas of medical science, including drug delivery, gene therapy, antimicrobials, biosensors and bio-labelling. Nanoparticles play a competent role as an anti-infection agent and thus act as efficient antiviral agents.

In the recent past, beneficial microorganisms have been sustainably used in agriculture as a safe, economic, and effective alternative to chemical fertilizers or pesticides. These beneficial microbes, including bacteria, actinomycetes, and yeast, were efficiently applied in soil, seeds, fruits, or plants as inoculants, to achieve the optimum agricultural yield. An efficient delivery method or enhanced shelf life of microbial inoculants in the soil or seed is still a matter of concern. The response of local genetic or ecological factors, after microbial applications, are also unknown and less studied. Therefore, Microbial Inoculants: Recent Progress and Applications fulfills the need to explore and learn about an efficient delivery mechanism, selection of microbial strain as inoculants, and related technological advances, for the efficient and productive use of microbial inoculants. Moreover, factors like methods of formulation, interaction between host plant and microbe, impact of inoculation on the metabolomics of plants, the effect of microbial inoculants on soil dynamics, proteomics approach of plant-microbe interaction, as well as the registration and regulation process of bio inoculants for commercial production are described in 16 chapters by the leading academicians and researchers from different parts of the world.

Microbial Biomolecules:  Emerging Approach in Agriculture, Pharmaceuticals and Environment Management explores and compiles new aspects of microbial-based biomolecules such as microbial enzymes, microbial metabolites, microbial surfactants, exopolysaccharides, and bioactive compounds and their potential applications in the field of health-related issues, sustainable agriculture and environment contamination management. Written for researchers, scientists, and graduate and PhD students in the areas of Microbiology, Biotechnology, Environmental Science and Pharmacology, this book covers the urgent need to explore eco-friendly and sustainable approaches to healthcare, agriculture and environmental contamination management.

Microbial Symbionts: Functions and Molecular Interactions on Host focuses on microbial symbionts of plants, animals, insects and molecular methods in the identification of microbial symbionts. The book describes the molecular mechanism and interactions of symbiosis of microbiome in plants, animals and humans. It brings the latest techniques for identification, localization and functional characterization of host-associated microbes and explains the role/importance of microbial symbionts. This comprehensive reference covers a wide range of symbiotic microorganisms used for basic and advanced techniques associated with the isolation, characterization and identification of microbial symbiotic microorganisms and their functions and molecular interactions on the host. The book will also helps users plan and execute experiments with appropriate knowledge rather than experimental trial and error in a wide range of disciplines, including Microbiology, Biotechnology, Botany and Zoology.