Bøger i Falk Symposium serien

In recent years functional gastrointestinal disorders have attracted much interest. These disorders are extremely common. They are characterized by symptoms and the lack of structural lesions that can be identified with clinically available routine diagnostic tests. Several functional abnormalities are now believed to play a role in the development of the symptoms. This book summarizes the presentations at the International Falk Symposium No. 99 `Functional Dyspepsia and Irritable Bowel Syndrome: Concepts and Controversies' that took place on May 27-28, 1997. This symposium brought together clinical and basic researchers and clinicians to improve interdisciplinary communication. The meeting comprehensively covered basic and clinical aspects of these disorders, and it not only summarized the current knowledge, but also identified scientific questions that need to be addressed in the future.

Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.

This book, the proceedings of Falk Symposium No. 125 on 'Cytokines in Liver Injury and Repair' (Progress in Gastroenterology and Hepatology Part II), held in Hannover, Germany, on September 30 - October 1, 2001, provides an update of our current knowledge on the role of cytokines in various human and experimental liver diseases and on their present and prospective use in therapeutic trials. The book contains chapters by most well-known experts in the field who have contributed significantly to our present knowledge on cytokines in liver injury and repair.

Treating patients with abdominal symptoms secondary to colonic diverticula is daily practice for general practitioners, gastroenterologists, surgeons and other physicians. At first sight, diagnosis and therapy seem to be straightforward. Nevertheless, discussions on details concerning understanding and management of this disorder often reveal differing views and immediately demonstrate that many questions remain unresolved.An approach to diverticular disease that is generally accepted is lacking. One reason may be that there is a certain paucity of scientific discussion. In contrast to other topics, diverticular disease is rarely found on the agenda of meetings and symposia.The book, the proceedings of Falk Symposium 148 on Diverticular Disease: Emerging Evidence in a Common Condition, held in Munich, Germany, on 17¿18 June 2005, covers many aspects of diverticular disease, from new scientific knowledge to exchange of clinical experience, and will provide much-needed information to basic scientists and clinicians alike.

In 1996, an international symposium entitled "Future Perspectives in Gastroenterology" was held in the city of Leipzig, State of Saxony, Germany. Leading scientists in diverse fields of gastroenterology presented their recent findings and undertook the propitious risk of speculating about future directions.

Proceedings of the Falk Symposium 153 held in Berlin, Germany, May 6-7, 2006

This book contains the proceedings of the XIIIth International Bile Acid Meeting (Falk Symposium 80), an official satellite meeting of the World Congress of Gastroenterology, held in San Diego, California, U.S.A., September 30--October 2, 1994.

Gallstones and gallstone diseases, therefore, are a frequent and important clinical problem. The book addresses the basic aspects of gallstone pathogenesis as well as the non-surgical and surgical treatment of gallstone diseases.

These cells are in contact with a number of other cell populations, including the largest part of the immune system, and with an excessive luminal antigen load, including vast numbers of bacteria.

Since the last International Bile Acid Meeting in San Diego in 1994, new advances have been made in the understanding of bile acid metabolism and transport.

Proceedings of the Falk Symposium 143 held in Freiburg, Germany, October 14-15, 2004

Since the last International Bile Acid Meeting in The Hague in 2000, bile acid research has continued to flourish and therapeutic use of bile acids has attained a broader role.

Thus, the pathogenesis of the two distinct familial colon cancer syndromes FAP (familial adenomatous polyposis) and HNPCC (hereditary non-polyposis colorectal cancer) is increasingly being understood.

Bile Acids in Liver Diseases, the proceedings of an International Falk Workshop held in Munich, January 1995, provides insights into current concepts in bile acid chemistry, bile acid synthesis and metabolism, and transport of bile acids across the hepatocyte.

Proceedings of the Falk Symposium 158 held in Seville, Spain, March 23-24 2007

Concerning the therapy of autoimmune liver diseases, corticosteroids and azathioprin remain the state of the art for autoimmune hepatitis, while bile acids have become well established in treatment of primary biliary cirrhosis as well as primary sclerosing cholangitis.

This book is the proceedings of a Falk Workshop held in Berlin, Germany, on January 23-24, 2003, which brought together experts in different fields of research to stimulate the transfer of findings from basic research to clinical application.

This book contains the proceedings of Falk Symposium 157, entitled Chronic Hepatitis: Metabolic, Cholestatic, Viral and Autoimmune, held in Freiburg, Germany, in October 2006: one of three symposia during the XIII Falk Liver Week 2006.

156 on Genetics in Liver Disease, part of the XIII International Liver Week 2006 held in Freiburg, Germany. In the tradition of the Falk Symposia, this book provides an exciting overview of current developments in the genetics of liver diseases, their diagnosis, treatment, and prevention.

Despite recent advances, the pathogenesis and therapy of various forms of chronic inflammatory diseases of the gastrointestinal tract remains problematical. and chronic inflammatory bowel diseases, particularly ulcerative colitis, are associated with an increased incidence of carcinoma.

The main focus of the book is to highlight the role of the immune system in gut and liver diseases and potential interactions of the gut and the liver respectively.

Sections cover viral hepatitis, immunosuppressive approaches in liver patients, malignant liver diseases, inflammatory liver diseases and complications of liver cirrhosis.

Sixty years after the misery of the Second World War and the destruction of Dresden and 20 years after a long and threatening Cold War, scientists from more than 50 nations across the world met in a wonderfully reconstructed city to discuss a series of key lectures on the pathophysiology and clinical management of liver cirrhosis.

There is currently an explosive growth of basic and clinical research in inflammatory bowel diseases.

Sections of this book, the Proceedings of the conference, are devoted to extraintestinal manifestations, cancer development, IBD in the context of pregnancy, and the assessment of disease activity, prognosis and quality of life.

Cytokines are synthesized and secreted in the liver by Kupffer cells, and are important for inflammation processes, the non-specific immune response, and probably the destruction and removal of tumour cells.

In several liver diseases, the underlying cause cannot always be eliminated, i.e. the progression of liver disease cannot be prevented. It is relevant for more than 40% of patients with HCV genotype 1 and up to 20% of patients with genotype 2 or 3. Several approaches are now underway to prevent or ameliorate mechanisms of disease progression.

In honour of Hans Popper's 100th birthday

During the last decade, knowledge about cholestatic liver disease and concomitant diseases, such as ulcerative colitis, cholangio- and hepatocellular carcinoma, pancreas and colon cancer, has increased considerably.

This book, the proceedings of a Falk Workshop on `Topical Steroids in Gastroenterology and Hepatology', held in Berlin, Germany, on 14 June 2003, critically discusses the current role of budesonide in gastroenterology, hepatology, surgery and oncology and focuses especially on potential new indications for the use of budesonide.