Bøger i Imaging in Medical Diagnosis and Therapy serien

The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional technically oriented quality assurance activities, but also general approaches regarding quality and safety. It includes contributions from experts both inside and outside the field to discuss both the processes and the people deliver

Detailing multi-modality image co-registration and radiobiology, this book discusses state-of-the-art strategies for patient simulation and immobilization, treatment planning, and dose calculation algorithms in stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT). It presents a comprehensive treatment of the field¿s history, major technological developments, clinical status, and practical considerations. The three main sections of the book cover delivery systems, precision patient positioning and immobilization, and treatment planning and dosimetry. The final section gives an overview of clinical outcomes and future directions for the field.

This text provides coverage of PET and SPECT instrumentation and multimodality imaging. It takes an integrative approach, bridging the researcher and clinician¿s perspectives. It begins with an introduction to basic physics of PET and SPECT, followed by a section on detector technology. It addresses various aspects of producing quantitative images, such as techniques for image reconstruction, corrections to the data to produce quantitative images, and dynamic imaging. It also discusses instrumentation for multimodality imaging and technologies used in pre-clinical imaging using PET and SPECT.

This comprehensive book provides a detailed introduction to plastic scintillation dosimetry and its use in the field of radiation dosimetry. Comprised of chapters authored by leading experts in the medical physics community, the text discusses a broad range of state-of-the-art technical implementations, from point source dosimetry scaling to 3D-volumetric and 4D-scintillation dosimetry. It addresses a wide scope of clinical applications, from machine quality assurance to small-field and in vivo dosimetry. It also examines related optical techniques, such as optically stimulated luminescence (OSL) or ¿erenkov luminescence.

This handbook collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. It provides practical details on animal ethics, models, and handling to assist researchers in planning and executing their small animal imaging studies. The book also explains how to measure and quantify images and explores a broad spectrum of disease types and disease sites where small animal imaging and therapy are currently applied, including cardiovascular disease and intracellular targets.

Due to improvements in image quality and the reduced cost of advanced features, ultrasound imaging is playing a greater role in the diagnosis and image-guided intervention of a wide range of diseases. Designed for individuals working on diagnostic and therapeutic applications, this book highlights the latest advances in using ultrasound imaging in image-guided interventions and ultrasound-based therapy. It presents current and emerging techniques, identifies trends in the use of ultrasound imaging, and addresses technical and computational problems that need to be solved.

This book gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. Basic principles are covered early on, and clinical applications become the focus thereafter. A final section introduces emerging models for cancer prevention and detection.

This book covers the major technical advances and methodologies shaping the development and clinical utility of CAD systems in breast imaging, chest imaging, abdominal imaging, and other emerging applications. The first section presents CAD technologies in breast imaging and the second section discusses CAD technologies in chest and abdominal imaging. The third section explores emerging CAD technologies in a wide range of imaging modalities designed to address a variety of diseases. The final section describes the current use of CAD systems in clinical practice.

Detailing multi-modality image co-registration and radiobiology, this book discusses state-of-the-art strategies for patient simulation and immobilization, treatment planning, and dose calculation algorithms in stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT). It presents a comprehensive treatment of the field¿s history, major technological developments, clinical status, and practical considerations. The three main sections of the book cover delivery systems, precision patient positioning and immobilization, and treatment planning and dosimetry. The final section gives an overview of clinical outcomes and future directions for the field.

This cutting-edge book presents a comprehensive overview of tomosynthesis, a new quasi-three-dimensional x-ray imaging technique that provides improved visualization of complex anatomic structures. The text covers technical aspects and clinical applications and offers detailed discussions of system design and image reconstruction strategies. It provides readers with an in-depth understanding of the process of image formation and the practical tools necessary to tailor their tomosynthesis systems for new clinical applications.

Reflecting recent advances in the field, this book provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. It explains how adaptive motion intervention is imaging-intensive and relies on near real-time image acquisition and processing. With a focus on the strategy of online motion compensation, the book discusses necessary motion detection methodology, repositioning methodology, and how to interpret and respond to target movement data in real time. It covers methods of detection and correction and then offers examples. It also gives attention to the distinct problems in dose planning and delivery posed by each adaptation technology.

This book explores the use of Monte Carlo methods for modeling various features of internal and external radiation sources. It addresses applications of the Monte Carlo particle transport simulation technique in radiation therapy, mainly focusing on external beam radiotherapy and brachytherapy. Along with presenting mathematical and technical aspects of the methods, the book discusses the modeling of medical linacs and other irradiation devices; issues specific to electron, photon, and proton ion beams and brachytherapy; and the optimization of treatment planning, radiation dosimetry, and quality assurance.

This comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. After an introduction to the first principles of radiation physics and radiation biology, the book discusses fabrication of nanoparticles, safety of nanoparticles, and the quantification of nanoparticle accumulation within tissues. Successive chapters highlight the computational and experimental techniques that underlie the use of nanoparticles for imaging and treating tumors. The book concludes with regulatory issues related to human use and a summary of envisioned clinical translation.

An up-to-date guide to using proton and carbon ion therapy in modern cancer treatment, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of the field. It covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. The book also gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy, offering detailed reports on the treatment of various cancers.

Radioembolization is now the preferred treatment for both primary and secondary liver cancer. This handbook addresses the radiation biology, physics, nuclear medicine, and imaging for radioembolization using Yttrium-90 (90Y) microspheres, in addition to discussing aspects related to interventional radiology. The contents reflect new on-label hepatic treatment indications, both in the US and worldwide, as well as dose-response relationships associated with radioembolization and the utility of adjuvant radioembolization and systemic chemotherapy.

This volume explains the biophysics and theory behind many MRI techniques and gives examples of how these techniques are applied in cancer diagnosis and treatment. The first section of the book presents basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. The next three sections cover image processing and characterizing tissue properties using endogenous and exogenous contrast mechanisms. The book concludes with emerging areas of MR cancer characterization, including radiation therapy planning, molecular and cellular imaging, pH imaging, and hyperpolarized MR.

This book is a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It also details key instrumentation and data mining technologies used in medical imaging informatics, as well as practical operational issues such as procurement, maintenance, teleradiology, and ethics.

Adaptive Radiation Therapy (ART) offers the promise of highly individualized radiation treatment for cancer patients through customized planning and delivery. This comprehensive book, the first focused on this evolving therapy, explores ways to optimize radiation plans. This includes the use of patient-specific 3D and 4D morphological and biological information to help define targets and individualize post-treatment assessment. It brings together world-class experts who discuss technologies for the delivery of treatments across various modalities. They also review clinical examples that demonstrate modern applications of ART for various cancers.