Bøger i River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine serien

Investigates the complexity of the determinants of burn out in different populations (health care professions, teachers, social workers etc.). Based on empirical study, the authors have developed a model of vulnerability to burn out which explains it as a specific complementary interaction between certain personality profile and the psychological climate of a work place.

It is important to understand the limitations of integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. This book focuses on some key advances in this field.

Understanding the molecular mechanisms of cancer is the key for transforming treatment. A substantial proportion of human genes show alternative splicing, and misregulation of Pre-MRNA splicing is seen in several cancers. This book investigates these matters.

Examines stem cell biology and regenerative medicine. This book covers many topics in the field and is based on seminars given by recognised scientists involved in the international master program on stem cell biology at the University Pierre and Marie Curie (UPMC) in Paris.

The Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book gathers together some of the ideas discussed during the third and fourth Disputationes Workshops held in Florence (Italy) and Aalborg (Denmark), respectively.

This book takes a whole new perspective concerning the approach to treating aging process. Most doctors feel they have no other options but to operate on the physical processes that occur as we grow older. Now, for the first time, there is another scientific approach that impacts on the causes of aging and not just on the effects.

Information on the changing epidemiology and expanding nosological range of Q fever in humans has gained much attention in the past decade. Q fever is a zoonotic disease caused by the highly infectious pathogen Coxiella burnetii and has global distribution with important health, social and economic implications. A number of other properties and characteristics of the causative agent and disease, define Q fever as a lasting and difficult veterinary and epidemiological problem, namely: the adaptability of C. burnetii and its high resistance in the external environment; the possibility of the existence of the agent in three- and two-member parasitic systems; the availability of natural and agricultural foci of infection; peculiarities of pathogenesis in humans and animals, and the mechanisms of excretion of the pathogen into the environment; and the high susceptibility of non-immune populations of animals and people. Given that C. burnetii is included in the arsenal of bacteriological weapons as agent with potential bioterrorist threat must be borne in mind the strategic importance of this microorganismThis book summarizes and analyzes the scientific facts and developments about Q Fever researched worldwide and performed by the author to propose a system for monitoring, control and prevention covering the main necessary actions, measures and activities in the fight against this fever. There is an uneven level of knowledge of Q fever in animals and humans in various countries on the planet, while the assessment of the relevance of the problem is often ambiguous and unrealistic in terms of veterinary, medical and social and economic aspects, which can result in an incomplete diagnosis, inaccurate information about the spread of disease and lack of purposeful struggle. The scientific topics discussed include: Biological, morphological and immunological properties of Coxiella burnetiiDiagnosis, clinical forms and manifestations, pathologic changesEpidemiology of Q fever in animals and humansPrevention and Control

Presents updated information about inflammatory bowel disease for health-care workers. The theoretical content is based on controlled and randomized clinical studies. Coverage includes all important topics required to understand ulcerative colitis and Crohn's disease.

The Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014.

Gathers the most innovative and scientifically robust knowledge and technologies on stem cells and involves investigators from academia and industry in formulating recommendations to standardize the isolation and manipulation of stem cells using solid and well-documented knowledge rather than fragmentary and often unrepeatable experimental reports.

Chlamydiae are a group of obligate intracellular microorganisms with a homogeneous group-specific antigenic structure, and a unique mode of development. The infections caused by them are unprecedented and wide-spread throughout the world, including a broad range of hosts among domestic and animal species and humans, and a variety of clinical manifestations. The uniqueness of chlamydia pathology consists mainly in the fact that the agents of the individual diseases are so close in their biological properties that they are represented only by the single genus Chlamydia, which includes all currently recognized species.Although chlamydiae and chlamydial infections were discovered a long time ago, they are still under-researched and relatively unknown to broad circles of microbiologists, virologists, epidemiologists and clinicians. A number of issues relating to molecular biology, pathogenesis, mechanisms of Chlamydia development and their interactions with cells, as well as their genetic conditioning and regulation, remain unclear. The same is true for ambiguities, problems and contradictions related to epidemiology, diagnostic approaches, immunity and vaccines. Based on scientific facts and the analysis of literature, and the experience of the author, Chlamydiae and Chlamydial Infections attempts to shed light on the cited problems, in terms of modern microbiology, cell biology and molecular biology. The scientific topics discussed include:* Biological, morphological and antigenic properties of Chlamydia spp* Genes, genomic structure and genetic regulations* Conventional diagnostic methods and examinations* Detection and differentiation of Chlamydia organisms by DNA detection systems* Clinical forms and manifestations and drug therapy* Pathology* Epidemiological peculiarities of Chlamydia - induced diseases in animals and humans* Immunity and vaccines

Covers numerous recent technological and research accomplishments in the area of nanomedicine and tissue engineering. This book follows recent trends in drug delivery systems, wound healing fields, cancer therapies, protection of teeth and also other health care systems.

This book focuses on established cardiovascular principles and highlights some of the progress achieved by recent research in the cardiovascular field. The authors report the basic concepts related to the functioning of the cardiovascular system necessary for medical students to understand. To foster learning, in each chapter the fundamental points are highlighted in italics and/or bold. In addition, we have added boxes that contain some more detailed information about physiological mechanisms or clinical aspects are analyzed and described in greater detail. The book describes the structure and function of the heart and vascular system for the reader to understand how the cardiovascular system responds in both health and disease. The book conveys a unified vision of the function of the heart and the vascular system, explaining the complexity of the system that goes far beyond the integrated connection between preload, afterload and cardiac contractility. The endothelium covers the internal part of the whole cardiovascular system; therefore, endothelial physiology is treated in several chapters. Given the importance of coronary circulation in cardiac pathophysiology, this special circulation is described in detail and enriched with the most up-to-date information. Several paragraphs and boxes on clinical implications are dedicated to the principles of electrophysiology and the electrocardiogram. A space is also dedicated to myocardial ischemia/reperfusion injury and cardioprotective procedures. The book is written in a linear and simple language without compromising the scientific rigor of the various topics covered.