Bøger i Topics in Current Genetics serien

This book provides a detailed presentation and comparison of the key nutritional regulatory mechanisms in lower as well as higher eukaryotes, written by recognised experts in this expanding field.

Molecular chaperones interact with virtually every newly synthesized protein. This volume assembles a collection of reviews on molecular chaperones that is both timely and basic. The book uniquely combines the basics of the subject area with the latest results.

All living cells are strictly separated from their surroundings by a membranous lipid bilayer. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters.

Many organisms have evolved the ability to enter into and revive from a dormant state.

The present book provides a comprehensive overview of our current knowledge on plastid biogenesis, plastid-nuclear communication, and the regulation of plastid gene expression at all levels.

Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored.This book provides advance information on RNA modification, including the associated editing machinery, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA molecules and hence the ability to influence the efficiency and accuracy of genetic expression. Outstanding scientists who are actively working on RNA modification/editing processes have provided up-to-date information on these intriguing cellular processes that have been generated over the course of millions of years in all living organisms. Each review has been written and illustrated for a large audience of readers, not only specialists in the field, but also for advanced students or researchers who want to learn more about recent progress in RNA modification and editing.

Recent advances in the understanding of these abiotic stress responses provided the impetus for compiling up-to-date reviews discussing all relevant topics in abiotic stress signaling of plants in a single volume.

Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached.

The present book provides a comprehensive overview of our current knowledge on plastid biogenesis, plastid-nuclear communication, and the regulation of plastid gene expression at all levels.

Many organisms have evolved the ability to enter into and revive from a dormant state.

This book defines the field of systems biology, one of the newest and fastest developing fields in science today. Cell biologists and other readers will discover many benefits for industry, such as the new network-based drug-target design validation.

Every cell has mechanisms to respond to changes in its environment and to adapt its growth and metabolism and the unicellular eukaryote yeast has long proven itself to be a particularly useful model system for the analysis of cellular stress.

In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies.

Transposable elements are short lengths of DNA with the capacity to move between different points within a genome. by using state-of-the-art strategies like "new generation sequencing." Moreover, the impact of transposable elements on plant genome structure and function is reviewed in detail, and also illustrated in examples and case studies.

Recent advances in the understanding of these abiotic stress responses provided the impetus for compiling up-to-date reviews discussing all relevant topics in abiotic stress signaling of plants in a single volume.

Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached.

The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways.

The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways.

This work offers a fascinating insight into a crucial genetic process. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field.

This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.

Transposable elements are short lengths of DNA with the capacity to move between different points within a genome. by using state-of-the-art strategies like "new generation sequencing." Moreover, the impact of transposable elements on plant genome structure and function is reviewed in detail, and also illustrated in examples and case studies.

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits.

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits.

In recent years, new yeast species have proven their value and novel biotechnological applications have emerged.

This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.

Giving a fresh, substantial and in-depth overview of the topic, this book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems.

Giving a fresh, substantial and in-depth overview of the topic, this book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems.

This work offers a fascinating insight into a crucial genetic process. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field.