Bøger i Topics in Medicinal Chemistry serien

With contributions by numerous experts

This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "e;disruptive"e; technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.

This volume provides an overview of neurodegenerative diseases. Topics include the role histone deacetylases plays in neurodegenerative diseases, phosphodiesterase inhibition as a way to target synaptic dysfunction in Alzheimer's disease, and more.

High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery.

Tactics in Contemporary Drug Design

With contributions by numerous experts

With contributions by numerous experts

With contributions by numerous experts

With contributions by numerous experts

With contributions by numerous experts

Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide.

High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery.

With contributions by numerous experts

Includes: "Protein-Protein Interactions as Drug Targets", "Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics", "The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer", and, "Protein-Protein Interaction Targets to Inhibit HIV-1 Infection".

Keller: Dengue Drug Discovery Dan Marquess: Recent Advances in Discovery and Development of Medicines for the Treatment of Secretory Diarrhea in the Developing World

Keller: Dengue Drug Discovery Dan Marquess: Recent Advances in Discovery and Development of Medicines for the Treatment of Secretory Diarrhea in the Developing World

This volume provides an overview of neurodegenerative diseases. Topics include the role histone deacetylases plays in neurodegenerative diseases, phosphodiesterase inhibition as a way to target synaptic dysfunction in Alzheimer's disease, and more.

This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology.

With contributions by numerous experts