Bøger i Woodhead Publishing Series in Biomaterials serien

The third edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons. This edition covers a range of updated and new content, ranging from chapters on materials analysis and selection, to methodologies and techniques used for joint replacement and clinical challenges of replacing specific joints. Key topics include tribological considerations and experiments; challenges in joint bearing surfaces; cementless fixation techniques; healing responses to implants. Clinical challenges and perspectives are covered with the aid of case studies. Thanks to its widespread collaboration and international contributors, Joint Replacement Technology, Third Edition is useful for materials scientists and engineers in both academia and the biomedical industry. Chemists, clinicians, and other researchers in this area will also find this text invaluable. This third edition provides an updated comprehensive review of recent developments in joint replacement technology. Reviews a range of specific joints, biological and mechanical issues and fixation techniques. Includes revised and new content, such as sections on regulatory affairs, AI techniques and 3D printing.

Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Details applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and its role in developing tissue scaffolds, and stem cell engineering

Structural Biomaterials: Properties, Characteristics, and Selection serves as a single point of reference to digest current research and develop a deeper understanding in the field of biomaterials engineering. This book uses a materials-focused approach, allowing the reader to quickly access specific, detailed information on biomaterials characterization and selection. Relevant to a range of readers, this book provides holistic coverage of the broad categories of structural biomaterials currently available and used in medical applications, highlighting the property requirements for structural biomaterials, their biocompatibility performance and their safety regulation in key categories such as metals, ceramics and polymers. The materials science perspective of this text ensures the content is accessible even to those without an extensive background in applied medicine, positioning this text not just for students, but as an overview and reference for researchers, scientists and engineers entering the field from related materials science disciplines.Provides a unique, holistic approach, covering key biomaterials categories in one text, including metals, ceramics and polymersDiscusses advantages, disadvantages, biocompatibility performance and safety regulations, allowing for accurate materials selection in medical applicationsUtilizes a materials science perspective, allowing those without an extensive applied medical background to learn about the field

Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering.Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterizationBridges the gap between biomaterials design and medical device manufacturingDiscusses the quality controls, standards, and FDA requirements for biomaterials and medical devices

Nanoengineered Biomaterials for Advanced Drug Delivery explores the latest advances in the applications of nanoengineered biomaterials in drug delivery systems. The book covers a wide range of biomaterials and nanotechnology techniques that have been used for the delivery of different biological molecules and drugs in the human body. It is an important resource for biomaterials scientists and engineers working in biomedicine and those wanting to learn more on how nanoengineered biomaterials are being used to enhance drug delivery for a variety of diseases. Nanoengineered biomaterials have enhanced properties that make them more effective than conventional biomaterials as both drug delivery agents, and in the creation of new drug delivery systems. As nanoengineering becomes more cost-effective, nanoengineered biomaterials have become more widely used within biomedicine. Offers an informed overview on how nanoengineering biomaterials enhance their properties for drug delivery applicationsDiscusses the major applications of nanoengineered biomaterials for drug deliveryOutlines the major challenges for successfully implementing nanoengineered biomaterials into existing drug delivery systems

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulationsProvides an overview on the cellular and molecular mechanisms involved in host responses to biomaterialsSystematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patientExplores the current generation of nanostructured 3D printed medical devicesAssesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Handbook of Ionic Substituted Hydroxyapatites provides scientists and researchers with comprehensive information on the synthesis processes of hydroxyapatite, also explaining the application of substituted hydroxyapatite. The book''s content is very structured and explanatory, starting with a detailed overview of biological apatite in bones and teeth, as well as a presentation of the analytical tools for hydroxyapatite. Bioceramics and the relative modern and emerging processing techniques are covered, as is 3-D printing, which has gained increasing importance within biomedical materials and in the use of hydroxyapatite in tissue engineering. Finally, the advantages and disadvantages of using ionic substitutions in clinical application are presented. Students and researchers in disciplines, such as Material Science, Ceramics, and Bioengineering will find this book to be very helpful in their work. It will also be a valuable resource for practitioners and surgeons in orthopedics, perio/implantology and maxillo-facial disciplines, and professionals working in R&D in ceramics and pharmaceuticals.Provides responses to the lack of scientific information about hydroxyapatites for biomedical applicationsSolves researchers'' issues regarding phase changes with respect to substituted ions and how these substitutions can alter/improve the properties of stoichiometric hydroxyapatiteExplains modern clinical applications and the effects of apatites within biomedical applications Includes both the advantages and disadvantages of using ionic substitutions in clinical application

Decontamination in Hospitals and Healthcare, Second Edition, enables users to obtain detailed knowledge of decontamination practices in healthcare settings, including surfaces, devices, clothing and people, with a specific focus on hospitals and dental clinics.Offers in-depth coverage of all aspects of decontamination in healthcareExamines the decontamination of surgical equipment and endoscopesExpanded to include new information on behavioral principles in decontamination, control of microbiological problems, waterborne microorganisms, pseudomonas and the decontamination of laundry