Biokemi

Biocatalyst Immobilization: Foundations and Applications provides a comprehensive overview of biocatalytic immobilization processes, as well as methods for study, characterization and application. Early chapters discuss current progress in enzyme immobilization and methods for selecting and pretreating enzymes prior to immobilization, with an emphasis on navigating common challenges and employing enzyme supports and post immobilization treatments to impact enzymatic activity. Process-based chapters instruct on measuring and reporting on enzyme immobilization efficiency, protein final content, quantification of reaction products, and the use of nanomaterials to characterize immobilized enzymes. Later chapters examine recent advances, including novel enzymatic reactors, multi-enzymatic biocatalysts, enzymatic biosensors, whole cell immobilization, the industrial application of immobilized enzymes, and perspectives on future trends.

This volume brings together world-leaders in the field of bioinorganic chemistry to discuss current mechanistic insights into the function of metalloenzymes.

Nano-enabled Sustainable and Precision Agriculture is the first single-volume resource to cover this important field using a whole systems approach that considers both opportunities and challenges. The book provides a comprehensive understanding of the role of nanotechnology in agriculture from broad aspects, but also includes a comprehensive view of the interaction of nanomaterials with soil-plant systems. It highlights aspects not described in previous books, including the application of nanoinformatics and artificial intelligence in nano-enabled sustainable agriculture, the application of nanotechnology in alternative forms of agriculture such as hydroponics, and regulatory frameworks for this research field. The book addresses all these aspects by including sections on enhanced sustainability, reduced pollution and enhanced ecosystems' health, and the role of nanoinformatics and machine learning.

Neuropsychiatric Complications of HIV: A Challenging Health Concern examines these neuropsychiatric complications prevalent in those who are HIV positive, providing clinical correlation, translational significance, and details guides to neurocognitive assessment, brain imaging, and related neuropharmacology. Written for clinicians, researchers, and students working with HIV and AIDS, the book begins with the biology of HIV, a complete look at available ARTs and antibodies, as well as diagnostics tools for HIV.It continues on to the epidemiology of NeuroAIDs and the manifestations of it-cognitive deficits, dementia, depression, agitation, psychosis, and cognitive slowing.

Biogenic Volatile Organic Compounds and Climate Change highlights the relationship between climate change and biogenic VOC and the impact they have on each other. Topics include the synthesis and emission of VOC in plants, how they respond to environmental stresses, how sustainable agricultural practices plants can be used to directly impact climate change beyond carbon sequestration, a review of biogenic VOCs as air pollutants, and the impact of biogenic VOC on clouds. This groundbreaking work is essential for anyone in climate change, global warming and cooling, atmospheric chemistry, clouds, fate and transport of chemicals in the atmosphere, air pollution, sustainability or agriculture.

Recent advances in the field of peptide chemistry and gene technology have resulted in an explosive accumulation of information on biologically active pep tides and functional proteins. Because of the importance of such peptides and proteins in the role of cellular or extracellular regulatory mechanisms and their potential therapeutic value, an understanding of their detailed interactions with the specific receptor should provide useful information for structure-activity studies. These problems have been approached in many ways. However, despite our efforts, many gaps in our knowledge of peptide chemistry remain to be filled, and some answers will no doubt be forthcoming in the next few years. This volume, the Proceedings of the 2nd Japan Symposium on Peptide Chemistry held in Shizuoka, covers all presentations. Speakers and discussants, numbering approximately 550, came from Australia, Austria, Belgium, Canada, China, Denmark, France, Germany, Israel, Italy, Russia, Sweden, Switzerland, India, the United Kingdom, the United States of America, and Japan. One very sad note was the sudden death, shortly before the conference, of Professor Emeritus Shiro Akabori, an outstanding organic chemist and a pioneer in peptide research. The news shocked his many friends and colleagues, who miss him deeply. Finally, it is a pleasure to acknowledge the help of those individuals and organizations who made the conference possible: the contributing scientists; the advisory committee and the staff of the conference; the Japanese Peptide Society, and other institutions; and the corporations which gave their financial support.

Bloodstain Pattern Analysis: Level 1 Lab Manual provides students with basic knowledge about bloodstain pattern analysis and the opportunity to conduct experiments to demonstrate the dynamics of blood in flight. The manual and associated exercises show how bloodstain pattern analysis is used as a forensic science discipline, illustrate the information that can be obtained from bloodstain evidence, and help students analyze actual bloodstain patterns. Upon completion of a course that uses this lab manual, students are qualified to join the International Association for Bloodstain Pattern Analysis, which is the first step toward taking the International Association of Identification Bloodstain Analysis certification test. The second edition features a new introduction, as well as a new chapter on cognitive bias written by Kelsey Backry. Additionally, the chapters have been expanded slightly to include greater depth of historical background for each topic. Bloodstain Pattern Analysis is a dynamic lab manual that is ideal for students taking introductory forensic science, law enforcement, or criminology courses. This resource could be especially helpful for active police officers and forensic scientists.

This second edition provides new and updated methods on the principles underlying modern protein analysis, from statistical issues to gel-based and mass spectrometry-based applications. Chapters detail protein quantification as basis for realisation of quantitative studies, gel-based and mass spectrometry-based quantification techniques, TMT, IPTL, PRM, MALDI Imaging, SILAC, PTM analysis, DIA, cross-linking, and the up-to-date topics of software and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Quantitative Methods in Proteomics, Second Edition aims to provide comprehensive and competent overview in the important and still growing field of quantitative proteomics.

The area of research on the health benefits of berries, their bioactive compounds and their related metabolites has exploded in the last 20 years resulting in new knowledge in the understanding of their metabolism, molecular mode of action as well as their clinical significance in promoting health and preventing chronic disease.Berries and Berry Bioactive Compounds in Promoting Health, reviews state-of-the-art research findings on this exponentially growing area. This comprehensive book brings together international experts in their corresponding fields with cutting-edge reviews. Exploring the effects and mechanisms of action of berry bioactive compounds and their metabolites on different body systems and chronic diseases, including their role on gut microbiota and eventual effect on health is the focus of this book. Unique topics covered, include the chemistry and analytical methods of detection of berry bioactive compounds, bioavailability, metabolism and factors that affect them including individual variability, their interaction with the gut microbiome, and their role and mechanism(s) of action on chronic diseases such as cardiovascular disease, diabetes mellitus, metabolic syndrome and obesity-induced inflammation, and cancer as well as neuroprotection and wound healing.It will be of benefit to scientists conducting research in the area of berries and their bioactive compounds on health and disease and for health care professionals, nutritionists, dietitians and clinical researchers, nutraceutical and natural food product developers (industry) and food regulators.

This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. Current advances in fields as diverse as space exploration, prebiotic chemistry and high-energy physics may help to provide an answer. Important pieces of information will come from observations at the two frontiers of science: outer space and the subatomic world. Observation of distant planets, galaxies, and even actual sampling of celestial objects from beyond the solar system are projects currently underway. At the other end of the spectrum, there are experiments that study the elemental properties of matter, such as symmetry, and interactions with the fundamental forces. Completely revised and updated this new edition once again unifies all the theories of the origin of biomolecular homochirality together in a single source. This complete, interdisciplinary review of an intriguing subject condenses a large and disparate range of contributions from journals in almost every scientific field. The various theories have been organized, interrelated and explained in a unified way. It is fundamental, comprehensive and structured to be accessible for educational purposes.

The term "reactive oxygen species" (ROS) refers to a group of reactive molecules and free radicals produced by molecular oxygen. In recent decades, there has been great interest in the role of ROS in various diseases. From basic science research to clinical trials, biomedical scientists have made rapid progress toward a better understanding of ROS-metabolizing systems and their role in health and diseases. This book includes sixteen chapters that address topics such as the history of ROS, its role in autoimmunity, neurodegeneration, and aging, and recent advances in various antioxidants and their therapeutic potential.

Volume 3 covers recent research with expanded coverage on this important area of remediation. Mycoremediation is the form of bioremediation in which fungi-based technology is used to decontaminate the environment. Fungi are among the primary saprotrophic organisms in an ecosystem, as they are efficient in the decomposition of organic matter. Wood-decay fungi, especially white rot, secretes extracellular enzymes and acids that break down lignin and cellulose. Fungi have been proven to be a very cost-effective and environmentally-friendly way for helping to remove a wide array of toxins from damaged environments or wastewater. These toxins include heavy metals, persistent organic pollutants, textile dyes, leather tanning industry chemicals and wastewater, petroleum fuels, polycyclic aromatic hydrocarbon, pharmaceuticals and personal care products, pesticides and herbicides, in land, fresh water and marine environments. Bioremediation of toxic organics by fungi is the most sustainable and green route for cleanup of contaminated sites and we discuss the multiple modes employed by fungi for detoxification of different toxic and recalcitrant compounds including prominent fungal enzymes viz., catalases, general lipase, laccases, peroxidases and sometimes intracellular enzymes, especially the cyrochrome P450 monooxygeneses.Fungi play an important role in the biogeochemical cycling of manganese and other redox-active metals, which is related to their ability to survive radiation and other oxidative challenges.This book covers recent research with more detail on the various types of fungi and associated fungal processes used to clean up wastes and wastewaters in contaminated environments, and discusses their potential for environmental applications.

Medical Microbiology is an excellent and easy-to-use textbook which explains the roles of microorganisms in human health and illness. Written in a clear and engaging manner, the book provides an overview of pathogenic organisms, their diagnosis and treatment tools as well as the molecular mechanisms of hostpathogen interactions and antimicrobial drug resistance.

This scarce antiquarian book is a facsimile reprint of the original. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions that are true to the original work.

The Regeneration Of Nerve And Muscle In The Small Intestine is a scientific book written by Walter Joseph Meek in 1910. The book is focused on the regeneration process of nerve and muscle cells in the small intestine. Meek provides a detailed analysis of the structure and function of these cells, and the mechanisms that enable their regeneration. The book covers various topics related to the regeneration process, including the role of stem cells, the effects of injury and disease, and the potential applications of this research in the field of medicine. The Regeneration Of Nerve And Muscle In The Small Intestine is a valuable resource for researchers, medical professionals, and students interested in the study of cell regeneration and its implications for human health.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major theory, but essentially to accepted knowledge. Aging at the Molecular Level examines the key elements in this transformation. Bringing together contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.

New Nerves For Old is a book written by Arthur Astor Carey and published in 1914. The book is a treatise on the subject of nervous disorders and their treatment, written for the layperson. It aims to provide a comprehensive understanding of the causes and symptoms of nervous disorders, as well as the various treatment options available at the time. The book covers a wide range of topics related to nervous disorders, including the role of diet, exercise, and rest in maintaining good health, the importance of mental and emotional well-being, and the use of various therapies such as hydrotherapy and massage. The author also discusses the impact of modern life on the nervous system, including the effects of stress, overwork, and other factors that can lead to nervous disorders. Overall, New Nerves For Old provides a valuable resource for anyone interested in learning more about nervous disorders and their treatment.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

In keeping with goal and style of the Handbook in Modern Biophysics series, the proposed book will maintain a chapter structure that contains two parts: concepts and biological application. The book also integrates all the chapters into a smooth, continuous discourse. The first and second chapters establish the mathematical methods and theoretical framework underpinning the different topics in the rest if the book. Other chapters will use the theoretical framework as a basis to discuss optical and NMR approaches. Each chapter will contain innovative didactic elements that facilitate teaching, self-study, and research preparation (key points, summary, exercise, references).

In the 100 years since the legume-Rhizobium symbiotic nitrogen fixation interaction was first described, interest in this field has grown rapidly. The types of studies have been cyclical in nature, involving a cross-section of disciplines. The availability of cheap nitrogenous fertilizers caused much of the biological nitrogen fixation research to become more theoretical in the developed world. The high cost of energy, coupled with environmental concerns and the interest in sustainable agriculture, has stimulated research in symbiotic nitrogen fixation. The development of modern genetic techniques has resulted in interdisciplinary research on plant-microbe interactions controlling nitrogen fixation. This has resulted in a better understanding of environmental factors influencing the nodulation process, chemical signalling between the symbiotic partners and the nature of the specificity between host plant and microsymbiotant. This volume summarizes the diverse research efforts in biological nitrogen fixation by presenting a collection of papers in the areas of physiology and metabolism, taxonomy and evolution, genetics and ecology.