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The present endeavor embodies studies pertaining to the development of nitrogen containing fused ring systems as potential central nervous system active agents. The thesis has been organized into three sections, each section includes five chapters. The studies cover all the aspects of medicinal chemistry research, starting from synthetic organic chemistry to biological activity and eventually the molecular docking of active compounds. Few privileged scaffolds have been identified for the current study. One of them is 3-benzazepine, a seven membered bicyclic benzoannelated fused ring system. Several protocols have been reported in literature for the cyclization and substitution on 3-benzazepine scaffold. As focus of the study was to synthesize C-1 substituted 3-benzazepin-2-one scaffold, a direct arylation method was tried with the help of palladium chemistry.
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This book has unfolded the reasons of the successful adoption of deep learning-based convolutional neural networks over machine learning- based artificial neural networks. The book has provided sufficient knowledge of the topics like Pandas and Numpy in Python programing language before switching to the core implementation of any Artificial Intelligence (AI) based algorithm. Thereafter, the theoretical concept of Artificial Neural Networks (ANN) and Convolutional Neural Networks (CNN) is discussed with step-by-step implementation in Python programing language. All the layers of the CNN model have been discussed in detail. Separate chapters are dedicated to the process of convolution, activation function, and pooling representing the theoretical concepts with practical implementation.This book is written for anyone interested in acquiring theoretical and practical knowledge of Artificial Intelligence. Students pursuing graduation and post-graduation in engineering in computer science can follow this book. In addition, this book will be very useful for candidates who are interested in the Artificial Intelligence-related research.For more details, please visit https://centralwestpublihing.com
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