Bøger af Cassiano Vasques Frota Guterres

The objective was to identify, through an in silico study , natural molecules characterized in the hydroalcoholic extract of Ocimum citriodurum in the laboratory that could act by antioxidant action, resembling experimental studies for teaching Organic Functions based on this interaction.According to the HPLC-MS methodology, 7 chemical constituents have been identified, most of which is rosmarinic acid, corresponding to 38.65%. Therefore, with the in silico activity, the active potential (Pa) determined for the hydroalcoholic extract of Ocimum citriodurum was exactly 0.547, thus identifying the antioxidant action present in it. By way of comparison, the reliability of the in silico study was tested in vitro. The extract also showed active antioxidant activity against the DPPH method, with a 50% efficient concentration (EC 50 ) of 50.53 mg/L. Furthermore, through the results of the similarity research, the Didactic Sequence (SD) was elaborated addressing the topic of bioactive molecules and antioxidants with the PASS Online and Pubchem server addressing the content of Organic functions.

The objective was to identify, through an in silico study , natural molecules characterized in the hydroalcoholic extract of Ocimum citriodurum in the laboratory that could act by antioxidant action, resembling experimental studies for teaching Organic Functions based on this interaction.According to HPLC-MS methodology, 7 chemical constituents were identified, most of which is rosmarinic acid, corresponding to 38.65%. Thus, with in silico activity, the active potential (Pa) determined for the hydroalcoholic extract of Ocimum citriodurum was exactly 0.547, thus identifying the antioxidant action in it. In comparison, the reliability of the in silico study was verified in vitro. The extract also showed active antioxidant activity against DPPH method, with a 50% efficient concentration (EC50) of 50.53 mg/L. In addition, through the results of the similarity search, the Teaching Sequence (SD) was developed by addressing the topic of bioactive molecules and antioxidants with the PASS Online and Pubchem server addressed to the content of Organic Functions.

Medicinal plants are presented as an alternative source for herbal and medicinal purposes, thus contributing to the treatment of various diseases. From this context, it can be stated that among the applications, prominent actions of essential oils stand out, which are characterized as volatile substances rich in chemical constituents, among the species, Origanum vulgare, Schinus terebinthifolia and Pimenta dioica stand out with a high EO content In this compass, these species contain secondary metabolites, which confer capacity for a wide spectrum of biological activities, such as ovicidal, larvicidal, adulticidal action, in addition to toxicity. It should be noted that such biological activities serve as parameters for pilot toxicological tests as a therapy for cancer cells. In this way, through the mentioned arguments, the OE's Origanum vulgare, Schinus terebinthifolia and Pimenta dioica and their respective nanoemulsions show themselves as a promising alternative to Aedes Aegypti and Artemia Salina.