Bøger af Dhekra Grami

The physicochemical/phytochemical characterization of prickly pear fruits as well as its actions on a certain number of physiological activities and digestive physiopathologies have been carried out. The study of their effect on the TGI confirmed that they possess anti-diarrheal activity. we have shown that acute pretreatment with fig juice and total extract allows a marked reduction in intestinal hypersecretion induced by castor oil. This inhibition is stronger by the juice compared to the total extract. They contain a significant antioxidant activity explained by its ROS scavenger effects. In the future, it will be a question of molecularly and more specifically characterizing the bioactive nutrients in order to determine the active principles and the exact mechanisms of action for the nutritional and pharmacological valorization of these fruits.

Many compounds, such as pesticides and certain plastics products, are suspected of being endocrine disruptors, i.e. "exogenous agents that interfere with the production, release, transport, metabolism, binding, action or elimination of natural hormones responsible for maintaining homeostasis and regulating the body's development", according to the US Environmental Protection Agency (EPA).The imbalance between the production of free radicals and their elimination systems leads to disorders of various organs, most notably those of the male reproductive system.In terms of reprotoxicity, our results revealed a reduction in the viability and motility of human spermatozoa, and an increase in the mitochondrial membrane potential (¿¿m) of human sperm.Our findings on the efficacy of Eruca sativa enabled us to determine its antioxidant power against free radical attack, thanks to its rich phenolic compound content, which acts as a scavenger of oxy-radicals.

Oxidative stress can be assessed at various levels: on the one hand, by measuring modified biological molecules, such as peroxidized lipids and oxidized proteins; on the other, by determining the antioxidant potential of superoxide dismutases (SOD), catalases and glutathione peroxidase (GPx). Secondly, antioxidant potential can be assessed by determining the enzymatic activities of superoxide dismutases (SOD), catalases and glutathione peroxidase (GPx). In terms of reprotoxicity, our results revealed a reduction in the net weight of male reproductive organs, with a decrease in the number of normal spermatozoa and their motility, and an increase in abnormal sperm with abnormalities of the head and tail. Our results on the efficacy of arugula (Eruca Sativa Mill) have enabled us to determine its antioxidant power against radical attack, thanks to its rich phenolic compound content, which acts as a scavenger of oxy-radicals.

In Tunisia, the use of medicinal plants is widely answered and occupies a major place in the treatment of various diseases. Our study allowed us to conclude the beneficial effects of the administration of the aqueous extract of the pomegranate in the prevention of the toxic effects of free radicals during oxidative stress. This work allowed us to reach the following conclusion: We have evaluated the antioxidant activity of the aqueous extract, furthermore, our results show that the extract of the plant (Punica granatum) causes an improvement of the antioxidant status at the hepatic level as well as the improvement of the transaminase (ASAT) and the plasma LDH. Indeed, the decrease of MDA concentration, increase of thiol group (GSH), superoxide dismutase (SOD) activity and catalase (CAT) activity at the hepatic level in rats treated with the extract show the antioxidant properties of Punica granatum. In conclusion, Punica granatum is a plant rich in therapeutic compounds.