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In this profound, complex story, G. Bennett Humphrey, MD, PhD, chronicles his year on 2 East, a pediatric leukemia floor. Doctors are fighting a presumedmortality rate of 100 percent, but the cost of finding a cure weighs heavily on their hearts. The cure rate for the children of 2 East in 1964 will turn out to be 15 percent. With almost no training in pediatrics and no experience with chemotherapy, the author confronts an entirely different world. From the beginning he is amazed by the strength of the mothers, the compassion of the nurses, and the admirable ways the children themselves cope with this devastating illness. Breaking Little Bones combines the personal and the scientific in poignant moments. It is both an overview of the revolutionary medical progress made in treating acute lymphocytic leukemia in 1964 and an honest narrative of what it was like to be there. Humphrey knew these kids. He knew Todd, who loved words, and Polly, who held her bald head proudly. He formed a brotherly bond with his team members, and he had to figure out his own unique way to cope with the grief. This transformative look into one of the most heartbreaking areas of medicine digs deep, revealing what we can learn about truly living from those facing an early death.
, Adrenal and Endocrine Tumors in Children' is the third volume in the series, 'Cancer Treatment and Research' devoted to pediatric oncology. Like its predecessors, it is organized into two sections. The first section again deals with issues of basic research germane to the understanding of childhood malignancies. In volume 3, the scope of the first section has been broadened to include a review that is epidemiologically oriented and a second review that is psychologically oriented. In the second part, major pediatric oncology units in Japan, Australia, Europe and the Americas have been invited to report their experience with of the multiple endocrine adrenal cortical carcinomas and the presentation neoplasia syndromes in children. In addition to these institutional reports of case material, there are reviews on genetics, pathology, and a diagnostic evaluation of children. The overview chapter on adrenal cortical carcinoma includes recommendations for radiotherapy from Dr. D' Angio and for che- motherapy from Dr. Philip Schein. Individuals using these recommended therapies are encouraged to report their results to the editors. The informa- tion will then be made available to others on request. List of Contributors ACTON, Dr. Ronald, Diabetes Research Hospital, Room 817, 1808 7th Ave. South, Birmingham, AL 35233, USA. BAUM, Edward S., M.D., Division of Hematology/Oncology, Northwestern University Medical School, Children's Memorial Hospital, 2300 Child- ren's Plaza, Chicago, IL 60614, USA. BENZ, Dr. Chris c., Dept. of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
In the second part, major pediatric oncology units in Japan, Australia, Europe and the Americas have been invited to report their experience with adrenal cortical carcinomas and the presentation of the multiple endocrine neoplasia syndromes in children.
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