Bøger af Jeremy Collins

Dendritic cells (DCs) refer to antigen-presenting cells of the mammalian immune system. The major job of the dendritic cells is to process antigen material and present it on the cell surface to the T cells of the immune system. They serve as messengers among the adaptive and innate immune systems. Dendritic cells are found in those tissues that come contact with the external environment, such as the skin and the inner lining of the stomach, nose, intestines and lungs. They can also be detected in the blood in an immature form. Dendritic cells are obtained from hematopoietic bone marrow progenitor cells, which first develop into immature dendritic cells and communicate continuously with other cells in the body. The communication can occur in the form of direct cell-cell contact on the basis of interaction between cell-surface proteins. This book aims to understand the immunobiology of dendritic cells. The topics included herein are of utmost significance and bound to provide incredible insights to the readers. Researchers and students engaged in the study of dendritic cells will be assisted by this book.

Dendritic cells are powerful antigen presenting cells which are significant for initiating the primary immune response. They travel to the lymph nodes when activated, where they interact with B and T cells to instigate and develop the adaptive immune response. They are the principal regulators of the immune system response and perform this function by linking the specificity of the adaptive response with the microbial sensing features of the innate immune system. Furthermore, these cells are effective in antigen presentation and are capable of acclimatizing to produce right amount of T cells as a response to a particular pathogen. Dendritic cells are also helpful in directing the immune system to react to foreign substances, simultaneously avoiding autoimmune responses. Altered function of dendritic cells is recognized to have a crucial role in autoimmune diseases and allergies, such as inflammatory bowel disease and lupus erythematosus. This book provides comprehensive insights into the role of dentritic cells in immunology. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in this area of study. Those in search of information to further their knowledge will be greatly assisted by this book.

A graphic-adventure that delves into why we pursue the wild outdoors