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Preterm birth refers to a condition when infant baby is born too early, before the completion of 37 weeks of pregnancy. There are four sub-categories of preterm birth which are defined on the basis on gestational age. These categories are extreme preterm, very early preterm, early preterm birth, and late preterm birth. Common causes of preterm birth include multiple pregnancies, infections, and chronic conditions such as diabetes and high blood pressure. The most frequent and severe type of injury during preterm birth is hypoxic ischemic encephalopathy (HIE) or perinatal asphyxia. HIE refers to brain damage that occurs due to inadequate supply of oxygen or blood flow in the brain. The common signs and symptoms of HIE are abnormal movements or seizures, weak cry, and organ dysfunction (especially of heart, kidney and liver). The signs of brain damage can be diagnosed using neuroimaging tests, such as through magnetic resonance imaging (MRI). This book includes some of the vital pieces of works being conducted across the world, on various topics related to neurodevelopmental outcomes of preterm birth. With its detailed analyses and data, it will prove immensely beneficial to professionals and students involved in this area at various levels.
Premature birth or preterm birth refers to the birth of a baby before completing 37 weeks of gestation, as opposed to full term delivery of approximately 40 weeks. Preterm birth may lead to various problems such as increased threat of morbidity and mortality, brain damage, and cerebral palsy. There are various factors that lead to the development of brain injury in preterm infants. Factors such as perinatal asphyxia, infection/inflammation, chronic hypoxia, and exposure to treatments such as mechanical ventilation, and corticosteroids causes severe damage to parts of the brain. One of the conditions which are caused due to brain damage in preterm infants is cerebral palsy. Children suffering from cerebral palsy (CP) face problem with hearing, speaking, sensation and vision. A child with cerebral palsy has impaired muscle tone, reflexes, motor development, and coordination. Brain damage can be prevented partly through maternal immunization and minimization of head traumas in children. This book aims to shed light on some of the unexplored aspects of preterm birth and related brain damage, and the recent researches related to it. Researchers and students engaged in this area of study will be greatly assisted by it.
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