Bøger af Kingsbury

1 The Genetics of Paramyxoviruses.- I. Introduction: The Genome Strategy of the Paramyxoviruses.- II. Genome Organization.- A. Genome Structure and function.- B. Coding Potential.- III. Genetic Interactions.- A. Absence of Genetic Recombination.- B. Complementation Analysis with Conditional Lethal Mutants.- C. Other Mutants.- IV. Analysis of Gene function.- A. Transport and Glycosylation of the G Glycoprotein of Respiratory Syncytial Virus.- B. Membrane Interactions of the F1 Polypeptide of SV5.- C. Gene-Specific Hypermutation in Measles Virus.- V Prospects.- VI. References.- 2 The Molecular Biology of the Paramyxovirus Genus.- I. Introduction.- A. History.- B. General Properties.- II. Virus Structure.- A. Morphology.- B. Virion Envelope and Envelope-Associated Proteins.- C. Internal Virion and Nonstructural Proteins.- III. Viral Replication.- A. Adsorption, Penetration, and Uncoating.- B. Molecular Organization of the Genome.- C. Transcription.- D. Genome Replication.- IV References.- 3 The Molecular Biology of the Morbilliviruses.- I. Introduction.- II. Genome Structure and Replication Strategy.- III. Genetic Relationships among the Morbilliviruses.- A. Nucleocapsid Protein Gene.- B. The Phosphoprotein Gene.- C. Matrix Protein Gene.- D. Fusion Protein Gene.- E. The Hemagglutinin Protein Gene.- F. The L Protein Gene.- IV. Function of the 5? and 3? Untranslated Regions.- V. Diagnosis Using Molecular Techniques.- VI. Morbillivirus Vaccines.- VII. Conclusions.- VIII. References.- 4 The Molecular Biology of Human Respiratory Syncytial Virus (RSV) of the Genus Pneumovirus.- I. Introduction.- II. Structures of the RSV Virion, RNAs, and Proteins.- A. Virion Structure.- B. Overview: Identification of Genomic RNA (vRNA), mRNAs, and Proteins.- C. Genetic Map of Strain A2.- D. Structures of the mRNAs.- E. Sequence Diversity among RSV Strains: Antigenic Subgroups.- F. Structures of the RSV Proteins.- III. RSV Replication.- A. Attachment, Penetration, and Growth Cycle.- B. vRNA Transcription.- C. vRNA Replication.- D. Virion Morphogenesis.- IV. Evolutionary Relationships.- A. RSV Antigenic Subgroups.- B. Relationships with Other Paramyxoviruses.- V. Conclusions.- VI. References.- 5 Evolutionary Relationships of Paramyxovirus Nucleocapsid-Associated Proteins.- I. Introduction.- A. Paramyxovirus Nucleocapsid Structure.- B. Functions of Nucleocapsid-Associated Proteins.- II. Sequence Analyses of Nucleocapsid Proteins.- A. NP Proteins.- B. L Proteins.- C. P Proteins.- III. Conclusions.- IV. References.- 6 The Nonstructural Proteins of Paramyxoviruses.- I. Introduction.- II. Paramyxovirus C Proteins.- A. Identification in Infected Cells.- B. The P and C Proteins are Encoded in Overlapping Reading Frames.- C. Multiple Initiation Codons on One mRNA.- D. Initiation Codon Consensus Sequences and the Scanning Hypothesis.- E. Subcellular Localization and Possible Function of Sendai Virus C Proteins.- F. When is a Nonstructural Protein a Structural Protein?.- G. Identification of C Proteins of Parinfluenza Virus 3, Measles Virus, and CDV.- III. Paramyxovirus Cysteine-Rich Proteins.- A. Identification of the Polypeptide and Its Gene in SV5.- B. Assignment of Coding Regions.- C. Strategy by Which P and V are Encoded.- D. Mechanism for the Addition of Extra Nucleotides to mRNAs.- E. Conservation of the Cysteine-Rich Region of Protein V in Paramyxoviruses.- F. Prediction of Cysteine-Rich Polypeptides and mRNAs with Extra Nucleotides in All Paramyxoviruses.- G. Identification of the Nonstructural Protein V and Its mRNAs in Other Paramyxoviruses.- H. Function of the Paramyxovirus Cysteine-Rich Protein V?.- IV. Paramyxovirus Small Hydrophobic (SH) Proteins.- A. Identification of the Polypeptide and Its Gene in SV5.- B. The SH Gene of Mumps Virus.- V Sendai Virus Nonstructural Polypeptide B: Intracellularly Phosphorylated Matrix Protein.- VI. Prospects.- VII. References.- 7 Paramyxovirus RNA Synthesis and P Gene Expression.- I. Paramyxovirus RNA Synthesis...

In this collection, leading scholars from around the world analyse 'megaregulation': a new intergovernmental economic ordering and form of governance. In the aftermath of the failure of TPP, the collection also looks at the controversies surrounding megaregulation and the future directions complex transnational governance may take.