Bøger af Michinori Oki

Organic chemical compounds exhibiting atropisomerism are important substances for investigating intermolecular interactions. They also demonstrate very interesting anomalities in reactivity of diastereotopic groups. This monograph is of particular interest to physical and to synthetic organic chemists. The author has investigated two particular classes of compounds that have stable rotational isomers at room temperature.

Rotation about the Carbon-Carbon single bond is generallyregarded to be unrestricted. About 50 years ago, rotationalisomers were found to exhibit optical activity: substitutedbiphenyl derivatives.From the contents: The "Free Rotation Concept" - RotamerPopulations - Barriers to Rotation - Reactivity ofRotational Isomers.