Bøger af Mithun Rudrapal

Comprehensive resource covering computational tools and techniques for the development of cost-effective drugs to combat diseases, with specific disease examples Computational Methods for Rational Drug Design covers the tools and techniques of drug design with applications to the discovery of small molecule-based therapeutics, detailing methodologies and practical applications and addressing the challenges of techniques like AI/ML and drug design for unknown receptor structures. Divided into 23 chapters, the contributors address various cutting-edge areas of therapeutic importance such as neurodegenerative disorders, cancer, multi-drug resistant bacterial infections, inflammatory diseases, and viral infections. Edited by a highly qualified academic with significant research contributions to the field, Computational Methods for Rational Drug Design explores topics including: Computer-assisted methods and tools for structure- and ligand-based drug design, virtual screening and lead discovery, and ADMET and physicochemical assessments In silico and pharmacophore modeling, fragment-based design, de novo drug design and scaffold hopping, network-based methods and drug discovery Rational design of natural products, peptides, enzyme inhibitors, drugs for neurodegenerative disorders, anti-inflammatory therapeutics, antibacterials for multi-drug resistant infections, and antiviral and anticancer therapeutics Protac and protide strategies in drug design, intrinsically disordered proteins (IDPs) in drug discovery and lung cancer treatment through ALK receptor-targeted drug metabolism and pharmacokinetics Helping readers seamlessly navigate the challenges of drug design, Computational Methods for Rational Drug Design is an essential reference for pharmaceutical and medicinal chemists, biochemists, pharmacologists, and phytochemists, along with molecular modeling and computational drug discovery professionals.

"Dietary Supplements and Nutraceuticals: Nutritional Requirements and Health Benefits" is the ultimate guide for students of Pharmacy and other health professional courses. This compilation covers all the basic and applied information in a concise and easy-to-understand manner.This book includes comprehensive coverage of dietary supplements, nutraceuticals, and functional foods including phytochemicals with their natural sources and detailed health benefits and medicinal uses.Written in a student-friendly style, this book would be a valuable resource to the readers to know about dietary supplements, nutraceuticals, and functional foods. Learning about the natural sources of phytochemicals, their dietary requirements and antioxidant role against human diseases would certainly be useful to the readers. This book will also fulfill the requirements of dieticians, hospital and clinical pharmacists, nurses and medical practitioners for dietary management in public health.

Understand polyphenols and their benefits with this comprehensive overview Polyphenols are a group of beneficial compounds--including phenolic acids, flavonoids, anthocyanins, and others--that can be found in a vast range of plants and plant-based foods. Their health benefits and the variety of their applications in functional foods, dietary supplements, and similar areas have made polyphenols a $1 billion market, a figure that is expected to more than double in the next decade. This has placed increased emphasis on areas of cutting-edge research such as the use of bio-based nanodelivery systems to improve the oral bioavailability of polyphenols. Polyphenols constitutes a comprehensive introduction to these compounds, their health benefits, and their potential nutraceutical applications. It incorporates both the biochemical fundamentals of polyphenols and their precise potential to prevent numerous common diseases. The result is an essential reference for a vital, growing area of research and industry. Polyphenols readers will also find: Detailed coverage of polyphenols' occurrence, bioactivity, and technological applications In-depth discussion of nano-based delivery systems to increase polyphenols' therapeutic efficacy and oral bioavailability and to reduce required dosages Guidance for developing treatments for cancers, cardiovascular diseases, inflammatory conditions, and more Polyphenols is ideal for food scientists and manufacturers, medicinal chemists, pharmaceutical scientists, and any biochemical or biomedical researcher or professional working with polyphenols or plant-based foods.

Children¿s health is tomorrow¿s wealth is one of the World Health Organization (WHO)¿s slogans in recent years. At birth, foetal weight is accepted as the single parameter that is directly related to the health and nutrition of the mother, and on the other hand, is an important determinant of the chances of the newborn to survive and experience healthy growth and development. This is because low birth weight (LBW) has been shown to be directly related to both immediate, long-term and very long-term development and well-being of the newborn. It is also a subject of increasing clinical and epidemiological investigations and a target for public health intervention.