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This book presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. This book is suitable for graduate students and researchers in the field of biology, medicine, bioinformatics and drug design and delivery.
Aimed at graduate students and researchers and including statistical models and analytical procedures, this book introduces the basic concepts and methods used in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture and related fields.
Presents developments in statistical methodology with a number of worked examples that outline how these methods can be applied. This title provides key tools needed to understand and model the genetic variation for drug response and equips statisticians with an understanding of this complex field and how computational skills can be employed.
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