Bøger af Rym Maamouri

Vogt-Koyanagi-Harada disease is an autoimmune inflammatory disease characterized by bilateral granulomatous panuveitis, associated with neurological, auditory and integumentary manifestations.Ocular involvement consists mainly of multiple retinal serous detachments, characteristic of the early stage, and depigmentation of the fundus, giving a "sunset" appearance characteristic of the late stage of the disease. Diagnosis is generally straightforward, based on a careful ophthalmological examination. Multimodal imaging plays an important role, not only in the diagnosis of doubtful cases, but above all in monitoring and assessing the prognosis of the disease. The prognosis is generally good, provided the diagnosis has been made in good time and treatment promptly initiated.

Introduction: Ocular involvement in sarcoidosis accounts for 11.8% of uveitis cases. The aim of our work is to study the clinical characteristics of patients presenting with sarcoidosis uveitis. Patients and Methods Retrospective study in the ophthalmology department. Results We included 9 patients (8 women and 1 man), 4 patients presented with initial ocular manifestations revealing systemic involvement whereas the diagnosis of systemic sarcoidosis preceded ocular involvement in 5 patients. The mean age at first consultation was 49 years (29-58). Ophthalmological involvement was bilateral in all patients, 2 patients (22%) had both anterior and intermediate uveitis and 4 patients (44%) had posterior involvement which was classified as panuveitis with retinal vasculitis in 1 case, panuveitis with multifocal choroiditis in 2 cases and panuveitis with retinal vasculitis and multifocal choroiditis in 1 case. Conclusion: Ocular involvement in sarcoidosis is common, and should be investigated in the presence of bilateral granulomatous uveitis.