Bøger af Siddhartha Mukherjee

Winner of the Guardian First Book Award 2011Winner of the Pulitzer Prize for Non-fiction 2011Shortlisted for the Wellcome Trust Book PrizeShortlisted for the Duff Cooper PrizeNow, as cancer becomes an ever more universal experience, the need to understand it, and its treatment, has never been more compelling. In this groundbreaking and award-winning account Siddhartha Mukherjee tells the fascinating story of our relationship with this disease. From brutal early surgical treatments, to Sidney Farber's hugely risky discovery of chemotherapy, to the author's treatment of his own patients, he reveals how far we have come in solving one of science's great mysteries and offers a fascinating glimpse of our future progress.

THE NEW YORK TIMES NUMBER ONE BESTSELLER BBC RADIO 4 BOOK OF THE WEEKThe Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.

"The story of the gene begins in earnest in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel, a monk working with pea plants, stumbles on the idea of a "unit of heredity." It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms postwar biology. It invades discourses concerning race and identity and provides startling answers to some of the most potent questions coursing through our political and cultural realms. It reorganizes our understanding of sexuality, gender identity, sexual orientation, temperament, choice, and free will, thus raising the most urgent questions affecting our personal realms. Above all, the story of the gene is driven by human ingenuity and obsessive minds -- from Gregor Mendel and Charles Darwin to Francis Crick, James Watson, and Rosalind Franklin to the thousands of scientists working today to understand the code of codes. Author of the Pulitzer Prize-winning bestseller The Emperor of All Maladies, Mukherjee draws on his scientific knowledge and research to describe the magisterial history of a scientific idea. Woven through The Gene is the story of Mukherjee's own family and its recurring pattern of schizophrenia, a haunting reminder that the science of genetics is not confined to the laboratory but is vitally relevant to everyday lives. The moral complexity of genetics reverberates even more urgently today as we learn to "read" and "write" the human genome -- unleashing the potential to change the fates and identities of our children and our children's children."--Book jacket, hardcover edition.

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prizewinning author of The Emperor of All Maladiesa fascinating history of the gene and ';a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick' (Elle). "e;Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself."e; Ken BurnsDr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. Mukherjee expresses abstract intellectual ideas through emotional stories[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry (The Washington Post). Throughout, the story of Mukherjees own familywith its tragic and bewildering history of mental illnessreminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentationfrom Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we areand what our manipulation of those genes might mean for our future (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. The Gene is a book we all should read (USA TODAY).

The book provides the whole horizon of process engineering and plant design from concept phase through the execution to commissioning of the plant in real practice. Providing a complete industrial perspective, it covers the pertinent guidelines and standards and how engineering documents are generated using these standards with relevant topics.

"From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee's revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer's exploration of what it means to be human. Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves--hearts, blood, brains--are built from these compartments. Hooke christened them "cells". The discovery of cells--and the reframing of the human body as a cellular ecosystem--announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia--all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces you with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate--a masterpiece"--

"Una magistral historia de la investigación sobre el cáncer" -Publishers WeeldyEsta es la historia más compleja de una de las enfermedades más extendidas de nuestro tiempo una crónica completa del cáncer desde sus orígenes hasta los modernos tratamientos que han surgido gracias a un siglo de investigación, ensayos y pequeños avances trascendentales en muchos lugares distintos. Al mismo tiempo es una reflexión sobre la enfermedad, la ética médica y la compleja relación entre los oncólogos y sus pacientes. La empatía que muestra Mukherjee hacia los enfermos de cáncer y sus familias, así como hacia los médicos que muy amenudo tan pocas esperanzas les pueden ofrecer, hacen de este libro un relato lleno de humanidad sobre una enfermedad compleja e inasible.ENGLISH DESCRIPTIONWinner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane "biography" of cancer-from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with-and perished from-for more than five thousand years.The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer." The book reads like a literary thriller with cancer as the protagonist.From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive-and to increase our understanding of this iconic disease.Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía» de una de las enfermedades más extendidas de nuestro tiempo.El emperador de todos los males es una crónica completa del cáncer desde sus orígenes hasta los modernos tratamientos (quimioterapia de diversos tipos, radioterapia y cirugía, además de la prevención) que han surgido gracias a un siglo de investigación, ensayos y pequeños avances trascendentales en muchos lugares distintos.Este libro es un repaso a la ciencia del cáncer y a la historia de los tratamientos que le han hecho frente, pero también es una reflexión sobre la enfermedad, la ética médica y las complejas y entrelazadas vidas de los oncólogos y sus pacientes. La empatía que muestra Mukherjee hacia los enfermos de cáncer y sus familias, así como hacia los médicos que muy a menudo tan pocas esperanzas les pueden ofrecer, hacen de este libro una historia llena de humanidad de una enfermedad compleja e inasible.Reseñas:«Esta obra debería valer a Mukherjee un merecido lugar en el panteón de los grandes divulgadores de nuestra era, junto a Carl Sagan, Stephen Jay Gould y Stephen Hawking.»The Boston Globe«Una magistral historia de la investigación sobre el cáncer.»Publishers WeeklyENGLISH DESCRIPTIONWinner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane "biography" of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years.The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer." The book reads like a literary thriller with cancer as the protagonist.From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease.Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

One of the world's premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine--and how understanding these principles can empower everyone.

Now in paperback, Siddhartha Mukherjee's instant New York Times-bestselling The Emperor of All Maladies, a 'magisterial' history of cancer--one of the New York Times Book Review's 10 Best Books of 2010. 'An extraordinary achievement." -The New Yorker "It's time to welcome a new star in the constellation of great writer-doctors. ' --Washington Post.