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Myeloproliferative neoplasia are clonal hematological malignancies characterized by excessive proliferation of blood cells. They group together different entities and can be classified according to the presence or absence of BCR-ABL rearrangement. We distinguish between chronic myeloid leukemia, classic BCR-ABL1-negative neoplasia including primary polycythemia; primary myelofibrosis and essential thrombocythemia; chronic neutrophilic leukemia; chronic eosinophilic leukemia (without further specification) and unclassifiable myeloproliferative neoplasia. This book is a review of what is known about myeloproliferative neoplasia and what has been learned so far.
The provision of medical biology consulting services is part of the development of the medicalization of the profession. It covers pre-analytical, analytical and post-analytical processes. This activity has become increasingly important in the diagnosis and management of patients with haemostasis disorders, and in monitoring their treatment. The implementation of a well-organized advice policy for the various recipients helps to strengthen the laboratory's involvement in patient care. The aim of this work is to propose guidelines to be followed in order to master the process of providing hemostasis advice.
The biological analysis laboratory plays an important role in the diagnosis of patients with haemostasis disorders. It provides the basis for monitoring antithrombotic therapies, both for patients treated with heparin and those on oral anticoagulants. It is therefore important to put in place the necessary control tools to ensure quality analysis results as quickly as possible.The aim of this paper is to set out documented approaches to quality control in the haemostasis analysis phase, in order to provide confirmation and permanent proof of the validity of results delivered at a reasonable cost, and to enable rapid and efficient detection of anomalies, without unnecessary alarms.
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