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In this book the authors provide an overview of COMMIT protocols that are used to coordinate participants in a distributed transaction so that all agree on the transaction¿s outcome. Presumed-abort and presumed-commit are the two best-known two-phase commit protocols. Presumed-abort is widely implemented. It handles aborting transactions efficiently and requires only a single forced log write at the coordinator in the common case that the transaction commits. It also handles read only transactions efficiently.
This book aims to develop a sophisticated Weather Web Application that provides users with comprehensive and real-time meteorological information. In an era where accurate and up-to-date weather data is crucial for various industries and individuals, this application seeks to deliver an intuitive and user-friendly interface for accessing diverse weather metrics.The book provides the comprehensive review and analysis of building the weather Application.
Humankind has been subject to infection by microorganism since before the dawn of recorded history. One presumes that mankind has been searching for suitable therapy for nearly as long. This was a desperately difficult enterprise given the acute nature of most infections and the nearly total lack of understanding of their origins prevalent until the last century. Although one can find indications in old medical writing of folkloric use of plant and animal preparations, soybean curd, moldy bread and cheese, counter infection with other microbes, the slow development of public health measures, and an understanding of the desirability of personal cleanliness, these factors were erratically and inefficiently applied and often failed. Until after the discovery of bacteria 300 years ago, and subsequent understanding of their role in infection about 150 years ago, there was no hope for rational therapy. The modern anti-infective era opened with the discovery of the sulfonamides in France and Germany in 1936 as an offshoot of Paul Ehrlich¿s earlier achievements in treating infections with organometallics and his theories of vital staining.
Cervical cancer is the second most common cancer among women in the developing world, and the largest cancer killer among women in most developing countries including India. Although, various drugs have been developed for cervical cancer, treatment with these drugs often results in a number of undesirable side effects, toxicity and multidrug resistance (MDR). Therefore novel approaches for the aggressive treatment of cervical cancer are urgently needed to decrease the side effects as well as toxicity, frequency of administration of existing drugs, to overcome MDR and to increase the survival rates. The book describes the development and evaluation of nanoparticles loaded scaffolds for selective and targeted delivery of doxorubicin to cervical cancer cells for the effective chemotherapy of cervical cancer.
Deadlock detection and resolution are the important strategies that are followed in database to control, detect and prevent deadlock. The book aims to discuss the fundamental concepts of deadlock and resolution strategies that can be adopted to handle deadlock. The deadlock resolution strategies discussed in the book can effectively control the deadlock situation in distributed database.
This book provides future research directions in energy, industry, and healthcare domain, and explores the different applications of IoT and its associated technologies. The book discusses software architecture, middleware, data processing and management as well as security, sensors and algorithms.
Concurrency In Database for controlling Multiple transactions and Maintaining the ACID properties.The efficient concurrency control technique is required for achieving the stable state of database before and after the execution of transaction.The book covers the importance of Concurrency technique.There are numerous of techniques available. The authors have analyzed the technique and came up with the importance of each technique in detail.
The study is an attempt towards developing a formulation of an anti-estrogen drug, which belongs to non-steroidal aromatase inhibitor and which has in-vitro dissolution profile similar to that of reference product. Our target is to develop a dosage form similar to reference product for generic drug application to abbreviated new drug application (ANDA). Immediate drug delivery is required to alter the pharmacokinetics and pharmacodynamics of pharmacological active moieties by using physiological parameters inherent in the selected route of administration. It is also desirable to show rapid onset of action. In case of patient needing a quick action, conventional tablets are unable to release medicament rapidly. The drugs having long half-life and more bioavailability are beneficial for the formulation of immediate release dosage forms. Therefore, the present project involves the development of a formula for an orally administrable immediate release tablet of an anti-estrogen drug, letrozole which must be stable, bio-equivalent to reference listed drug product and has a reproducible and robust process of medication to prevent breast cancer relapse.
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