Bøger udgivet af Elsevier Ltd

Combining informative, meticulously crafted prose with more than 4,000 high-quality images, Osborn's Brain, third edition, is a comprehensive, easy to understand, and visually stunning learning curriculum from highly esteemed author Dr. Anne G. Osborn. This fully revised edition provides a solid framework for understanding the complex subject of brain imaging, integrating relevant information from Dr. Osborn's entire career of accumulated knowledge, experience, and interest in neuropathology, neurosurgery, and clinical neurosciences. While neuroradiologists will find intriguing, thought-provoking insights included especially for them in every chapter, Osborn's Brain is an excellent review resource for physicians at all levels of expertise-from seasoned radiologists and neurosurgeons to new and senior residents or fellows. Combines essential anatomy with gross pathology and imaging, clearly demonstrating why and how diseases appear the way they do and helping readers think clearly about diagnoses, types of diagnoses, and the various pathologies that can affect the brain Guides readers through the "must know" aspects of neuroimaging and neuropathology (brain trauma, stroke, vascular lesions, etc.) before zeroing in on such topics as infections, demyelinating and inflammatory diseases, neoplasms, toxic-metabolic-degenerative disorders, and congenital brain malformations Provides state-of-the-art coverage on such topics as new brain tumor entities, the effects of emerging viral illness such as COVID-19 on the brain, and recently delineated/named diseases (e.g., HIV-associated CD8 encephalitis) Features more than 4,000 stunning, high-resolution radiologic images and 100+ detailed, full-color medical illustrations, all of which are annotated to describe the most clinically significant features; and includes robust, digital-only galleries that contain hundreds of additional images that further illustrate each chapter Includes up-to-date nomenclature based on the 5th edition of the WHO Classification of Tumors, Central Nervous System, including a complete revision, expansion, and updating of CNS neoplasms with new entities, revised grading criteria, diagnostic molecular pathology, and nomenclature Contains Dr. Osborn’s trademark summary boxes for a quick review of essential facts, signature graphics with additional radiological and pathologic correlations, and up-to-the-minute literature references Includes an eBook version¿that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Easy to read and follow, Essentials of Equipment in Anaesthesia, Critical Care and Perioperative Medicine makes an otherwise dry subject digestible and easy to learn. This practical textbook comprehensively covers all the equipment used in the operating theatre and intensive care unit, including why it is used and any related safety concerns. It has been fully updated in its sixth edition to include new technologies introduced during the Covid-19 pandemic. This is ideal as the main text for all trainees undertaking the primary FRCA exams and is also suitable anyone who works with anaesthetic equipment, including anaesthetic and intensive care nurses and operating department practitioners. It features concise and consistent text and illustrations, self-assessment features, and exam tips. Portable, concise and simply formatted - a perfect practical companion Clear coloured images and illustrations bring the text to life Follows the Royal College of Anaesthetists postgraduate training and exam syllabus Summary boxes, more than 100 exam style questions, and OSCE stations and exam tips all aid the reader in exam revision Covers new equipment and fully updated relevant to current practice Suggested further reading fully updated New information on: Aladin Cassettes; Glostavent machine; CONTRAfluran system; videolaryngoscopy and high definition camera use in intubation and endoscopy; use of ultrasound in epidural; Penthrox; NRFit devices; Cell saver; ECMO

Written by leading experts in this field, Evidence-Based Physical Therapy for the Pelvic Floor provides physiotherapists and other professionals with knowledge and confidence to bring the latest evidence-based approaches and treatment strategies for addressing pelvic floor dysfunction to their practice. Fully updated and with a wealth of new information, this edition includes sections on devices and apps, gynaecological cancer, sexual dysfunction, fistula, clinical use of EMG, anal incontinence and pain, as well as a discussion of sexualized violence by Nobel Peace Prize winner Denis Mugwege and his team.New and fully updated contents; new authors and new chapters provide contemporary evidenceInnovative practice guidelines supported by a sound evidence baseColour illustrations of pelvic floor anatomy and related neuroanatomy/neurophysiologyMRIs and ultrasounds showing normal and dysfunctional pelvic floorKey summaries for easy navigationFull colour throughout

Using a practical, question-and-answer approach, Evidence-Based Practice of Palliative Medicine, 2nd Edition, helps you provide optimal care for patients and families who are dealing with serious illness. This unique reference focuses on patient and family/caregiver-centered care, highlighting the benefits of palliative care and best practices for delivery. The highly practical, user-friendly format sets it apart from other texts in the field, with concise, readable chapters organized around clinical questions that you’re most likely to encounter in everyday care. Uniquely organized using a question-and-answer approach, making it easy to find answers to common questions asked by practitioners and patients. Up-to-date, reader-friendly chapters explore interventions, assessment techniques, treatment modalities, recommendations and guidelines, communication techniques, and available resources for palliative care. Expanded discussions on hospice in every chapter, and a new emphasis on pediatrics, with increased material on pediatric malignancies, developmental delays, cystic fibrosis, and perinatal palliative care. New chapters on wellness of the palliative care practitioner, patients with opioid use disorders, telehealth in palliative care, health disparities, rural palliative care, caring for people with hematologic malignancies, integrative and alternative therapies, LGBTQ+ populations, mobile health technologies, and national palliative care implementation strategies. High-quality evidence gathered and reviewed by leading experts in palliative medicine, including clinicians, educators, and researchers across a broad range of disciplines. Numerous algorithms throughout help you make informed decisions, and "take-home" points in every chapter provide a quick summary of key content. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text and figures from the book on a variety of devices. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

**Selected for Doody’s Core Titles® 2024 in Dermatology**For dermatology residents and trainees, as well as those in clinical practice, Dermatology is the leading reference for understanding, diagnosing, and treating the full spectrum of skin disease-and is the key resource that residents rely on throughout their training and certification. Widely recognized for its easy-in, easy-out approach, this revised 5th Edition turns complex information into user-friendly visual content through the use of clear, templated chapters, digestible artwork, and easy-to-follow algorithms and tables. This two-volume masterwork provides complete, authoritative coverage of basic science, clinical practice of both adult and pediatric dermatology, dermatopathology, and dermatologic surgery-more than any other source, making it the gold standard reference in the field today.Simplifies complex content in a highly accessible, highly visual manner, with 1,100+ tables; 2,600+ figures, including numerous disease classification algorithms as well as diagnostic and therapeutic pathways; and over 1,500 additional figures and tables online.Utilizes weighted differential diagnosis tables and a "ladder" approach to therapeutic interventions.Features an intuitive organization and color-coded sections that allow for easy and rapid access to the information you need.Retains an emphasis on clinicopathologic correlations, with photomicrographs demonstrating key histologic findings adjacent to clinical images of the same disorder.Contains updated treatment information throughout, including immune checkpoint inhibitors, JAK inhibitors, and monoclonal antibodies for a wide range of conditions such as psoriasis, atopic dermatitis, alopecia areata, vitiligo, and skin cancers.Provides up-to-date information on genetic and molecular markers and next-generation sequencing as it applies to dermatologists.Features new videos, including cryosurgical and suturing techniques, treatment of rhinophyma via electrosection, and neuromodulator treatment of axillary hyperhidrosis.Includes new WHO classifications of skin tumors, new FDA pregnancy drug labeling, and new ACR/EULAR criteria for vasculitis and lupus erythematosus.Includes new sections on confocal microscopy and artificial intelligence.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

This volume in the best-selling "Case Review" series uses hundreds of case studies to challenge your knowledge of a full range of topics in brain imaging. With 170 brand new cases, new coverage of MRA, CTA, MR spectroscopy and multi-detectors and over 600 brilliant images, this is your ideal concise, economical, and user-friendly tool for self assessment in this specialty!Presents 150 high-yield case studies organized in three levels of difficulty, helping you build your knowledge and confidence in stages.Captures the latest clinical implications and diagnostic pearls on brain conditions that you will be tested on.Includes multiple-choice questions, answers, and rationales that mimic the format of certification exams.Uses short, easily digestible chapters covering the full range of brain imaging for efficient, effective learning and exam preparation.Features hundreds of high-quality images representing a wide range of clinical situations encountered in brain imaging. Images include MRA and CTA, as well as advanced techniques such as MR perfusion and MR spectroscopy to help you expand your image interpretation and diagnostic skills.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Making the correct diagnosis is the first step in the effective management of patients in pain, and simplifying the diagnosis is the primary focus of Atlas of Common Pain Syndromes, 5th Edition. Dr. Steven D. Waldman provides clinicians with a clear, concise, and up-to-date understanding of the most common pain syndromes encountered in day-to-day practice, along with practical insights on how to diagnose and treat them. Featuring more than 1,000 high-quality illustrations, this unique atlas provides the information needed to make the correct diagnosis-the signs and symptoms associated with each syndrome, the testing needed to confirm the working diagnosis, and the differential diagnosis-in addition to the available treatment options.Covers more than 130 common pain conditions, including headache, facial pain, brachial plexus pain, fibromyalgia, arthritis, neuropathy, bursitis, gastrointestinal pain, sports injuries, musculoskeletal pain, and much more.Contains 13 new chapters covering Angina, Pulmonary Embolus, Pneumothorax, Gastroesophageal Reflux Disease, Peptic Ulcer Disease, Abdominal Aortic Aneurysm, Spigelian Hernia, Ectopic Pregnancy, Lyme Disease, Sciatic Nerve Entrapment at the Knee, Tibial Nerve Entrapment at the Knee, Saphenous Neuralgia, and Metatarsalgia.Uses a consistent, easy-to-follow visual format, and features more than 1,000 high-quality, clearly labeled illustrations, tables, and radiologic and ultrasound images-many new to this edition-that provide rich visual guidance and simplify making the correct diagnosis.Includes a "Side Effects and Complications" section and a "Clinical Pearls" section in every chapter that help you avoid potential pitfalls associated with each common pain syndrome.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Offering a step-by-step, practical approach to increasingly requested cosmetic procedures, Procedures in Cosmetic Dermatology: Surgical Lifting, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. Edited by expert surgeons Drs. Hooman Khorasani and Eyal Levit, along with hand-selected experts in each individual area, it covers minimally invasive surgical lifting techniques that can be performed by dermatologic surgeons-all abundantly illustrated and evidence based. A substantial video library demonstrating surgical lifting techniques helps you successfully incorporate the latest procedures into your practice.Provides complete, clear descriptions and rationales for the evaluation, management, and execution of surgical and advanced non-surgical rejuvenation of the face and neck.Covers brow and forehead lifting, upper and lower eyelid blepharoplasty, the Asian eyelid lift, facelift, modern neck lift, thread lifting, face contouring procedures, and skin resurfacing and tightening.Features high-quality images and approximately 50 procedural videos demonstrating exactly how to perform facelift, thread lift, browlift, and blepharoplasty procedures.Presents real visual aging to identify the festoon formations-one of the most difficult areas to handle in the rejuvenation of the lower eyelids and face.Includes a detailed chapter on accrediting and building a state-approved operating room and photography room, and includes information on how to reduce the risk of COVID transmission through proven air system UVC devices.Shares the knowledge and expertise of a leading cosmetic dermatological surgeon in every chapter, along with other specialists (facial plastic, plastic, oculoplastic, and oral maxillofacial surgery) who are proficient in each technique and have reviewed and added their pearls to the procedure.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

A guide to physical examination for Nurse Practitioners and other primary care providers. It helps you develop the range of skills required to assess children of all ages.

Steels: Structure, Properties and Design is an essential text and reference, providing indispensable foundational content for researchers, metallurgists, and engineers in industry and academia. The book provides inspiring content for undergraduates, yet has a depth that makes it useful to researchers. Steels represent the most used metallic materials, possessing a wide range of structures and properties. By examining the properties of steels in conjunction with structure, the book provides a valuable description of the development and behavior of these materials- the very foundation of their widespread use. The new edition has been thoroughly revised and updated with 2 new chapters, expanded content throughout,and yet it retains its clear writing style, extensive bibliographies, and real-life examples. One of the new chapters deals with the additive manufacture of steels with a focus on structure and properties. The other has visionary applications of steel that lead to a dramatic reduction of the carbon dioxide burden, within a short period of time, and without compromising the quality of life that depends on steels.

Bacterial Biogeochemistry: The Ecophysiology of Mineral Cycling, Fourth Edition discusses the influence of bacterial activity on the chemical environment of the biosphere. Following the success of previous editions, this update focuses on bacterial metabolism and its relevance to the environment, including the decomposition of soil, food chains, nitrogen fixation, assimilation, and reduction of carbon nitrogen and sulfur, and microbial symbiosis. All chapters have been revised and brought up-to-date in light of the many advances and discoveries that have taken place during the last decade. The scope of the new edition has broadened to provide a review of the processes and phenomena that are relevant for global change feedback loops and advances in bacterial biogeochemical cycles.

Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only "pocket-size" quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products - CAR-T cells.

Bioprocess Engineering Principles, Third Edition provides a solid introduction to bioprocess engineering for students with a limited engineering background. The book explains process analysis from an engineering perspective using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology, such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. With new and expanded material, this remains the book of choice for students seeking to move into bioprocess engineering

This latest offering from the highly regarded Ross & Wilson stable provides a sound, evidence-based grounding in pathophysiology for anyone studying or working in the allied health professions It covers normal physiology and the associated pathophysiological processes that lead to disease. The underlying science is clearly explained and linked to clinical situations, relating the changes in normal physiological function directly to onset and progress of disease, providing the exact level of detail you'll need in your professional practice. Ross & Wilson's Pathophysiology is clearly written and easy to understand, with beautiful illustrations and enhanced navigation to make learning this important subject a pleasure. Clear, engaging and straightforward writing style - suitable for nurses as well as paramedics, physiotherapists, midwives, radiographers and clinical physiologists Comprehensive explanations of the underlying science, linked to clinical scenarios so readers can relate learning to practice Cross-referencing to allow for easy navigation across different sections Draws on the latest evidence and up-to-date research Beautifully illustrated with clear, well-labelled figures, photographs and diagrams

Make efficient, accurate diagnoses and prepare for imaging exams with a multitude of differential diagnoses accompanied by hundreds of high-quality, unknown cases in neuroradiology. Neuroradiology: Key Differential Diagnoses and Clinical Questions, 2nd Edition, helps you master the skills you need for interpreting imaging of the head, neck, brain and spine for adults and children. All-new cases and extensively revised content throughout bring you up to date and equip you to reach a definitive diagnosis for common, complex, and rare cases. Applies pattern analysis techniques to distinguish similar-looking diagnostic considerations.  Shows how diagnostic ambiguities are resolved by comparing and contrasting different entities.  Includes numerous new differential diagnoses.  Provides new and extensively revised content on pediatric neuroradiology, including more complex cases such as symmetric diffusion abnormality in an infant, cortical malformations, and complex spinal dysraphism.  Helps you avoid diagnostic pitfalls by recognizing significant variations in the clinical presentation of different diseases.  An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Current, comprehensive, and evidence-based, Kaplan's Cardiac Anesthesia: Perioperative and Critical Care Management, 8th Edition, offers practical guidance from today¿s international leaders in cardiac anesthesiology, helping you to optimize perioperative outcomes, avoid complications, and ensure maximum patient safety. Dr. Joel A. Kaplan, along with an expert team of associate editors, guides you through today¿s clinical challenges, including expanded coverage of critical care, the newest approaches to perioperative assessment and management, state-of-the art diagnostic techniques, and cardiovascular and coronary physiology. Covers the full spectrum of contemporary cardiothoracic anesthesia practice, including preoperative assessment, physiology, pharmacology, monitoring, transesophageal echocardiography, coagulation, specific cardiac procedures, extracorporeal circulation, postoperative pain treatment, and management of the complex patient with cardiac disease.   Includes expanded coverage of critical care topics, reflecting the increased perioperative care now provided by anesthesiologists in the ICU.  Contains new chapters on Structural Heart Disease Procedures; Cardiorespiratory Effects of COVID-19; Critical Care Ultrasound; Intensive Unit Management of Patients on Mechanical Circulatory Support; and Postoperative Care of the Heart and Lung Transplant Patient.   Features more than 900 full-color illustrations, decision trees, charts, and graphs (over one-third are new) that aid in visual understanding of complex topics.   Provides access to over 120 videos, including a range of echocardiography clips.   Contains balanced, dependable, and updated content on all aspects of the anesthetic management of cardiac surgical procedures, as well as cardiology procedures performed in catheterization and electrophysiologic laboratories.  Places new emphasis on cardiac devices requiring perioperative care, including cardiac implanted electrical devices and ventricular assist devices.  An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Offers coverage of musculoskeletal anatomy and helps you develop the working knowledge of muscles you'll need for successful manual therapy practice.

Part of the renowned Braunwald family of references, Cardiovascular Intervention: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on every aspect of catheterization of the heart and vasculature and the latest imaging technologies. This practical reference on interventional cardiology is organized from a procedural perspective, with chapters focused exclusively on how to manage complex cardiovascular disease. Now fully updated from cover to cover, the 2nd Edition offers authoritative and current point-of-care coverage of this highly complex, technology-driven specialty-an ideal resource for practitioners at all levels of experience.Offers concise, focused coverage of all aspects of managing interventional cardiology patients, highlighting cautions, procedural nuances and tips, and outcomes.Covers all the newest catheterization techniques and equipment, including new-generation stents, mechanical support devices, imaging technology, and closure devices.Offers complete coverage of structural heart disease and new developments in heart valve disease, including TAVI and mitral valve procedures.Provides updates on the latest procedures, devices, and clinical guidelines for evidence-based practice.Uses a clear, easy-to-follow organization with separate sections on coronary artery interventions, peripheral artery interventions, cerebrovascular interventions, venous interventions, structural heart interventions, and congenital heart disease.Features more than 506 high-quality illustrations and access to 176 procedural videos.An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

5G Advanced: The Next Generation Wireless Access Technology, Third Edition follows the authors' highly celebrated books on 3G and 4G by providing a new level of insight into 5G NR. After an initial discussion of the background to 5G, including requirements, spectrum aspects and the standardization timeline, all technology features of the first phase of NR are described in detail. Included is a detailed description of the NR physical-layer structure and higher-layer protocols, RF and spectrum aspects and co-existence and interworking with LTE. This book provides a good understanding of NR and the different NR technology components, giving insight into why a certain solution was selected.

Part of the renowned Braunwald family of references, Hypertension: A Companion to Braunwald’s Heart Disease provides today’s clinicians with clear, authoritative guidance on every aspect of managing and treating patients who suffer from hypertensive disorders. An invaluable resource for cardiologists, endocrinologists, and nephrologists, this one-stop reference covers all the latest developments from basic science to clinical trials and guidelines related to the treatment of common to complex hypertension. Now fully updated from cover to cover, the 4th Edition offers unparalleled coverage of hypertension in an accessible and user-friendly manner. Thoroughly covers new treatment guidelines related to recent research and the latest physiologic understanding for a wide range of patients with hypertension and related co-morbidities. Includes new chapters on Hypertension in Women, Mineralocorticoid Receptor Antagonists, Exercise and Hypertension, and Telemedicine/Digital Health. Contains new or expanded content on epidemiology, pathophysiology, immunology, clinical findings, laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, prognosis, and management. Provides new chapter summaries and a new focus on clinical and actionable content using a streamlined, narrative format. Covers behavior management and prevention as an integral part of hypertensive and pre-hypertensive treatment plans. Highlights combination drug therapies and management of chronic complications of hypertension. Offers expert guidance from worldwide experts in cardiology, endocrinology, and nephrology, and integrates the most recent guidelines from leading organizations around the world. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Part of the renowned Braunwald family of references, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on every aspect of the latest diagnosis and management options for patients with arrhythmias. This comprehensive reference on cardiac arrhythmias lays a solid foundation of the underlying mechanisms of cardiac electrophysiology with an emphasis on identifying, understanding, and treating individual arrhythmias. Now fully updated from cover to cover, and carefully written to provide continuity and a consistent message throughout, the 4th Edition offers unparalleled coverage of cardiac arrhythmias in an accessible and user-friendly manner. Grounds clinical techniques in basic science for managing patients with complex arrythmia disorders.  Offers increased clinical content with complete diagnostic and management options, including the latest drug-based, device-based, and device-drug therapies.  Covers new tools and techniques for atrial transseptal and percutaneous pericardial access, new ablation energies and tools, and new ACC/HRS guidelines for bradyarrhythmias.  Contains a new chapter on stroke prevention in atrial arrhythmias.  Includes significant content updates on macro-reentrant atrial tachycardias in an era of ultra-high-resolution mapping, new mapping and ablation technologies for ventricular tachycardia, new genetic mechanisms underlying arrhythmia syndromes, and much more.  Provides access to dozens of videos depicting key mapping techniques, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, and atrial septal puncture, as well as pericardial access, cryoablation, and left atrial appendage exclusion procedures.   Uses a consistent format throughout, showing every arrhythmia in a similar manner for quick reference.  An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Written with useful practicality in mind, Breast Pathology, 3rd Edition, provides surgical pathologists with authoritative guidance on the selection and best use of proper diagnostic techniques when reporting on breast specimens. Dr. David J. Dabbs and a team of internationally acclaimed pathologists incorporate genomic and molecular information, gross and microscopic findings, radiologic and laboratory diagnosis, theranostics, and immunohistochemistry to cover every aspect of benign and malignant lesions of the breast, helping you minimize diagnostic variation and error in the sign-out room. Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer.  Incorporates the latest classifications of breast pathology and molecular diagnosis.  Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry.  Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter.  Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting.  Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval.  Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease.  Includes biomarker guideline updates throughout.  Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.   Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Designed with the busy practitioner in mind, ExpertDDx: Brain and Spine, third edition, quickly guides you to the most likely differential diagnoses based on key imaging findings and clinical information. This superbly illustrated resource covers more than 275 of the top differential diagnoses across a broad spectrum of central nervous system diseases, presenting parallel groups of anatomically based differentials, generic imaging patterns, modality-specific findings, and clinically based differentials for each area. Now fully revised and up-to-date, this practical reference clearly guides you through useful, actionable differential diagnoses that lead to definitive findings in every area of the brain and spine. Presents multiple clear, sharp, succinctly annotated images for each diagnosis; a list of diagnostic possibilities sorted as common, less common, and rare but significant; and brief, bulleted text offering helpful diagnostic clues  Reflects changes in 2021 WHO CNS tumor grading and nomenclature  Contains newly identified entities, new differential diagnoses, and updated references  Shows both typical and variant manifestations of each possible diagnosis  Includes more than 7,000 high-quality print and online images   Features updated genetic information now available in Online Mendelian Inheritance in Man (OMIM)  Separates adult and pediatric DDx lists for even faster reference  Assists you in building either a definitive diagnosis from an imaging study or a carefully refined list of reasonable differential diagnoses  Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Brewing Microbiology: Managing Microbes, Ensuring Quality and Valorising Waste, Second Edition covers micro-organisms of significance to the brewing industry, including the most recent threats to beer quality and stability that have emerged. Reflecting the significant surge in production of no- and low-alcohol (NOLO) beers and Hard Seltzers since the publication of the 1st edition, and the lack of information available on the increased microbiological risk associated with these beverages - and how to control them, a new chapter "Maintaining microbiological quality control in Hard Seltzers and NOLO beverages" provides best practices in ensuring safe and effective management in production and stability. Sustainability and the environment have been at the forefront of brewers strategic thinking for many years. The first edition of Brewing Microbiology included coverage of anaerobic treatments of brewery waste and waste-water treatment. This section has been expanded to cover recent innovations in the valorization of brewery waste streams, such as biotransformation of brewers spent grains.

Meticulously reviewed and updated for today's medical students, Basic Immunology, 7th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume has been fully revised to include recent important advances in our understanding and knowledge of the immune system. A student favorite through six outstanding editions, this new edition uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help you master this complex topic in the most efficient, effective manner possible. Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application.  Contains new and expanded content on pandemics, COVID-19, and herd immunity; resistance and susceptibility to COVID-19; RNA vaccines and hybrid viral vaccines; tumor immunotherapy; innate immune responses to viruses; mechanisms of immunologic tolerance; and immunotherapy for autoimmune, allergic, and other inflammatory diseases, and cancer.  Provides unrivalled instruction from an expert author team, all of whom are experienced teachers, course directors, and lecturers.  Features a highly readable writing style and practical organization, now with fully revised content and updated images to cover new information and improve reader understanding of complex concepts.  Provides additional online features such as answers to in-book chapter review questions and self-assessment questions.  Presents information in a format and style that maximizes usefulness to students and teachers of medicine, allied health fields, and biology.  Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review.  An eBook version is included with purchase. The eBook allows you to access all the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Previous edition: 2016 published under title: Thompson & Thompson genetics in medicine

The fifth edition of this well-loved manual for understanding and using Muscle Energy Techniques (METs) presents clear guidelines for their applications, resting on the newest scientific research and embedded in the framework of whole-person health care. It provides a comprehensive, evidence-based how-to guide for applying MET in the treatment of some forms of musculoskeletal dysfunction, to alleviate pain, and support functional movement. Packed with colour illustrations and complemented by more than 50 instructional videos featuring Leon Chaitow demonstrating the techniques described, Muscle Energy Techniques 5e guides the reader through both theory and practice, with an emphasis on evidence-informed clinical reasoning and application. This fifth edition reconvenes the international team of expert contributors originally selected by Leon Chaitow to present the role of METs in a range of clinical settings and scenarios. These include the use of METs for treating a wide range of acute and chronic pain conditions, prevention and management of trauma and injuries in athletes, and their successful incorporation into physiotherapy, chiropractic, osteopathic, massage therapy, and rehabilitation environments. New chapters and sections embed the use of METs in the biopsychosocial framework for whole-person healthcare based on the latest guidelines. Includes case studies and guidance for clinical practice. Entirely new research review chapter presents the latest research findings underpinning MET methodology and develops considerations regarding evidence-informed practice with attention to current debates. Updated chapter on the history of MET explains the impact of historical context on clinical practice. Increased emphasis on pulsed MET and updated research on the role of isotonic eccentric stretching and isometric eccentric contractions in rehabilitation, strengthening, and restoring functionality. Developed section and references to fascia research and its implications for MET. Updates in all chapters prioritizing whole-person healthcare. Fully updated references throughout with close cross-referencing between chapters and awareness of international context and research developments. This book is ideal for all professionals with an interest in manual and movement therapy, including osteopaths, physiotherapists, exercise scientists, chiropractors, acupuncturists, manual therapists, massage therapists, and personal trainers.