Bøger udgivet af Elsevier Science & Technology

Mathematical Modeling, Simulations, and Artificial Intelligence for Emergent Pandemic Diseases: Lessons Learned from COVID-19 includes new research, models and simulations developed during the COVID-19 pandemic into how mathematical methods and practice can impact future response. Chapters go beyond forecasting COVID-19, bringing different scale angles and mathematical techniques (e.g., ordinary differential and difference equations, agent-based models, artificial intelligence, and complex networks) which could have potential use in modeling other emergent pandemic diseases. A major part of the book focuses on preparing the scientific community for the next pandemic, particularly the application of mathematical modeling in ecology, economics and epidemiology. Readers will benefit from learning how to apply advanced mathematical modeling to a variety of topics of practical interest, including optimal allocations of masks and vaccines but also more theoretical problems such as the evolution of viral variants.

"Green Energy Systems: Design, Modelling, Synthesis and Applications provides a comprehensive introduction to the design, modeling, optimization and application of predictable and alternative energy systems. With a strong focus on the fundamentals, the book provides an overview of the energy potential and conversion topology of green energy sources, the design and analysis of off grid solar and wind energy sources, and their application in effective energy management in rural communities. Sections address energy systems from solar, wind, biomass, and hybrid energy sources, and include discussions of power electronic circuit topologies for energy conversion in both off and on grid systems. The second part of the book addresses energy harvesting at different scales, with a particular emphasis on micro energy harvesting for low power electronics like wearable devices. A wide range of applications are also discussed, alongside their challenges and solutions. Finally, case studies are presented on select topics to give readers deeper insights into the real-world applications discussed. Introduces the fundamental principles underlying green energy systems, their characterization, analysis, modelling, and evaluation. Includes a wide range of applications of new functional materials for next-generation devices. Provides supporting data and calculations alongside real-world case studies"--

Plant Hormones in Crop Improvement examines the signaling pathways and mechanisms associated with phytohormones, with particular focus on stress resilience. The growing population of world and unpredictable climate puts pressure on the agriculture production. Current constraints such as increasing temperatures, drought, salinity, cold, nutrient deficiency, along with biotic interactions trigger exquisitely tuned responsive mechanisms in plants. The main coordinators of all stress-related mechanisms are phytohormones, which can be transported over long distances and play a significant role in controlling physiological, agronomic and growth traits, metabolites and sustained crop productivity. Therefore, understanding the mechanisms influencing the stress responses mediated by phytohormones is crucial to ensure the continuity of agricultural production and food security. This book aims to address sustainable agricultural approaches to improve biotic and abiotic stress resilience in crop plants, covering different topics from perception and signaling plant hormones to physiological and molecular changes under different cues. Plant Hormones in Crop Improvement is an essential read for students, researchers and agriculturalists interested in plant physiology, plant genetics and crop yield improvement.

Nuclear Decommissioning Case Studies: Organization and Management, Economics, and Staying in Business is the fifth volume in Michele Laraia‿s series, which presents a selection of global case studies on different aspects of nuclear decommissioning. This volume focuses on organization, economics and performance experience, offering the reader guidance on project management, staffing, costs and funding, and training. It guides those responsible for the planning and implementation of nuclear decommissioning to ensure thorough and reliable applications. Decommissioning experts, including regulators, operating organizations, waste managers, researchers, and academics will find this book to be suitable supplementary material to reference works on the theory and applications of nuclear decommissioning. Readers will obtain an understanding of many key case studies, including what happened and what they can learn from the events quoted, to help supplement, solidify, and strengthen their understanding of the topic.

Overcurrent Relay Advances for Modern Electricity Networks explores how to optimize protection and improve system stability and resilience by implementing advanced overcurrent relays in highly dynamic renewable heavy power systems. This guide provides a foundation in relay functions and behaviors in current modern networks, particularly regarding renewable power sources and new electrical network structures such as microgrids. The work discusses the design and creation of protection schemes in smart grids and analyzes their impact on performance and security in protection systems. This practical book also presents a critical new coordination method for online applications.

Power System Protection in Future Smart Grids: Achieving Reliable Operation with Renewable Energy, Electric Vehicles and Distributed Generation demonstrates how to protect smart, highly renewable, and highly distributed power systems with state-of-the-art methods rooted in adaptive protection and dynamic response, and based on continuous communication. Focusing on the implementation of novel protection schemes, each chapter presents solutions accompanied by figurative elements and demonstrator codes in MATLAB, C, Python and Java. Chapters address active distribution networks, hybrid microgrids, EVs and inverters on fault levels, adaptive protection systems, dynamic protection strategies, and Hardware in the Loop (HiL) approaches.

Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.

State Space Systems with Time-Delays Analysis, Identification and Applications covers the modeling, identification and control of industrial applications, including system identification, parameter estimation, dynamic simulation, nonlinear control, and other emerging techniques. The book introduces basic time-delay systems, architectures and control methods. Emphasis is placed on the mathematical analysis of these systems, identifying them, and applying them to practical engineering problems such as three independent water tank systems and distillation systems. This book contains a wide range of time-delay system identification methods that can help readers master the system controllers' design methods.

Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches. Sections discuss fundamental characteristics of biosurfactants, their physio-chemical properties, and their differences from chemically synthesize surfactants, different research approaches for the study of known biosurfactants, and the genetic manipulation of microorganisms to increase biosurfactant productivity, or to produce molecules with improved characteristics. Throughout the book, methods and approaches are discussed in easy-to-digest formats, with methods discussed, ranging from in silico approaches to classical biocatalysis omics analysis and metabolic engineering.

Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

Ticks: Biology, Ecology and Diseases provides a detailed overview of the fascinating world of tick biology and ecology. This book discusses disease transmission to humans and livestock, assesses the impact of human behavior and climate change on tick biology, and details how this will affect future disease transmission. Written by an expert on ticks and their transmitted diseases, this book explores the unique biology of ticks and how it influences the transmission of some of the most devastating diseases. In a series of detailed chapters, the book provides up-to-date information on the interrelationship between ticks and the vertebrates they feed on. In addition, the book covers information on recent scientific discoveries surrounding ticks, along with reviews on control methods and disease transmission. Other sections cover the recent emergence of tick-borne pathogens, making this book an ideal source for interested scientists, clinicians, veterinarians and experts in the field of tick biology.

Therapeutic Monoclonal Antibodies: From Lot Release to Stability Testing is a highly topical resource on a subject of interest for scientists and researchers working on monoclonal antibodies' characterization, release testing, stability testing and similarity assessments of monoclonal antibodies in the biopharmaceutical industry. Monoclonal antibodies (mAbs) are large, extremely complex and dynamic biomolecules, so it can be challenging to develop well-characterized therapeutic antibodies that meet regulatory expectations that are also in-line with commercialized standards for different drug markets. Lot release testing and understanding the stability of the mAb over a period of time, and in different environmental conditions, is an indispensable aspect of mAb physicochemical characterization. This book covers the process, including extensive analysis that starts with quantifying the purity attribute to glycan profiling and identifying the mAb primary structure. The book has a primary purpose of focusing on both Lot release testing and stability testing of monoclonal antibodies (subjects not covered in any great detail in other books).

With the rapidly growing demand for mental health care there is a need for efficient and effective psychological treatment options. Low Intensity Psychological Therapy has become well established in the England Improving Access to Psychological Therapies (IAPT) programme as a beneficial and versatile treatment option for mild-moderate symptoms of depression and anxiety. A Pragmatic Guide to Low Intensity Psychological Therapy: Care in High Volume, provides a guide to Low Intensity Psychological Therapy from the perspective of the Low Intensity Practitioner. This book describes the Low Intensity role as part of a multi-disciplinary approach to psychological care. The authors use a series of case vignettes, personal experience and current literature to help navigate the context of the role and its potential for ethical and safe expansion.

Petroleum engineers search through endless sources to understand oil and gas chemicals, identify root cause of the problems, and discover solutions while operations are becoming more unconventional and driving toward more sustainable practice. Oil and Gas Chemistry Management Series brings an all-inclusive suite of tools to cover all the sectors of oil and gas chemistry-related issues and chemical solutions from drilling and completion, to production, surface processing, and storage. The fourth reference in the series, Surface Process, Transportation, and Storage delivers the critical basics while also covering latest research developments and practical solutions. Organized by the type of challenges, this volume facilitates engineers to fully understand underlying theories, practical solutions, and keys for successful applications. Basics include produced fluids treating, foam control, pipeline drag reduction, and crude oil and natural gas storage, while more advanced topics cover CO2 recovery, shipment, storage, and utilization. Supported by a list of contributing experts from both academia and industry, this volume brings a necessary reference to bridge petroleum chemistry operations from theory into more cost-effective and sustainable practical applications.

Tight Oil Reservoirs: Characterization, Modeling, and Field Development, the latest release in the Unconventional Reservoir Engineering Series, delivers a full spectrum of reservoir engineering guidelines so that the engineer can focus on every stage of development specific to tight oil. Covering characterization, micro- and nano-scale modeling, drilling horizontally, completing hydraulic fracturing, and field development, each section includes case studies, practice exercises, and future references for even deeper understanding. Rounding out with coverage on field economics and remaining challenges, this book puts control in the engineer's hands.In this ongoing series, each release will discuss the latest resources, explain their importance in the market, show the benefits of the resource through the latest research, provide details and protocols on how to evaluate and develop the resource, and give case studies and practice questions to gain practicality.

Nematode Diseases of Crops and their Sustainable Management focuses on methods to recognize and identify nematode attackers in agriculturally important crops, offering ecologically sustainable and economically viable strategies and measures for the management of nematode infestations and diseases. The book analyzes nematode pests as major constraints in global crop production and explores the limitations of existing nematode management technologies. It offers comprehensive information through individually focused chapters on major nematode problems in internationally important food, fiber and beverage crops as well as in mushrooms, polyhouse agriculture and forest flora with regard to distribution, and much more.In view of the highly damaging nature of the disease complexes and complexity in their management, independent chapters on nematode-fungus and nematode-bacteria disease complexes and their management are also presented.

Neglected and Underutilized Crops: Future Smart Food explores future food crops with climate resilience potential. Sections cover their botany, nutritional significance, global distribution, production technology, and tolerance to biotic and abiotic stresses of neglected and underutilized crops. By simply changing species in a crop rotation system, the cycle of some pests and diseases is disrupted and probabilities of infestations are reduced. Finally, the book provides case studies that highlight where the adaptation of crops to local environments, especially with regard to climate change, have been successful. These crops can help make agricultural production systems more resilient to climate change. Although a few books on neglected and underutilized crops are available, this comprehensive book covers the full scope of crop husbandry, nutritional significance and global distribution.

Theory of mechanisms is an applied science of mechanics that studies the relationship between geometry, mobility, topology, and relative motion between rigid bodies connected by geometric forms. Recently, knowledge in kinematics and mechanisms has considerably increased, causing a renovation in the methods of kinematic analysis. With the progress of the algebras of kinematics and the mathematical methods used in the optimal solution of polynomial equations, it has become possible to formulate and elegantly solve problems. Mechanisms: Kinematic Analysis and Applications in Robotics provides an updated approach to kinematic analysis methods and a review of the mobility criteria most used in planar and spatial mechanisms. Applications in the kinematic analysis of robot manipulators complement the material presented in the book, growing in importance when one recognizes that kinematics is a basic area in the control and modeling of robot manipulators. Presents an organized review of general mathematical methods and classical concepts of the theory of mechanisms Introduces methods approaching time derivatives of arbitrary vectors employing general approaches based on the vector angular velocity concept introduced by Kane and Levinson Proposes a strategic approach not only in acceleration analysis but also to jerk analysis in an easy to understand and systematic way Explains kinematic analysis of serial and parallel manipulators by means of the theory of screws

Although scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood. Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment. Epigenetics and DNA Damage, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation. Early chapters address the basic science of DNA damage and its association with various epigenetic mechanisms, including DNA methylation, post-translational histone modifications, histone variants, chromatin remodeling, miRNAs, and lncRNAs. This is followed by a close discussion of DNA damage and epigenetics in metabolism, aging, cellular differentiation, immune function, stem cell biology, and cancer, tying recent research to translational application in disease understanding. Later chapters examine possible epigenetic therapies combining DNA damage induction and epigenetic alteration, as well as instructive chapters on how to analyze DNA damage and epigenetic alterations in new research.

Advances in Resting-state Functional MRI: Methods, Interpretation, and Applications gives readers with basic neuroimaging experience an up-to-date and in-depth understanding of the methods, opportunities, and challenges in rs-fMRI. The book covers current knowledge gaps in rs-fMRI, including "what are biologically plausible brain networks," "how to tell what part is noise," "how to perform quality assurance on the data," "what are the spatial and temporal limits of our ability to resolve FC," and "how to best identify network features related to individual differences or disease state". This book is an ideal reference for neuroscientists, computational neuroscientists, psychologists, biomedical engineers, physicists and medical physicists. Both new and more advanced researchers alike will be able to discover new information distilled from the past decade of research to become well-versed in rs-fMRI-related topics.

Power-to-Gas: Bridging the Electricity and Gas Networks introduces the concept of Power-to-Gas (P2G) technologies in the Whole Energy System framework and related Vector-Coupling Technologies (VCTs). The boo provides a comprehensive approach to the economic, technical and environmental evaluation of P2G technology to make more effective use of the surplus power of renewable units. It covers converting electricity to hydrogen or methane, and the challenges, analytical solutions and future trends of P2G applications. Moreover, the reference features technology overviews and literature reviews in each chapter, along with concepts, appropriate definitions, fundamentals and contexts in the energy systems. Finally, modeling issues and requirements for analysis Gas and Power Vector-Coupling Technologies are presented and supported by real-world case studies and experimental examples. By uniquely analyzing issues from the whole energy system perspective, this book plays a pivotal role in supporting researchers and academicians in electrical, mechanical and energy engineering in their long-term decarbonization strategies.

1. Fundamentals of optical devices -- 2. Basic mechanisms and instrumentation for optical measurement -- 3. Characterization of optical devices -- 4. Optical fiber measurement -- 5. Fiber-based optical metrology and spectroscopy techniques -- 6. Optical system performance measurements -- 7. Measurement errors.

Obesity Epidemic and the Environment: Latin America and the Caribbean Region provides a broad analysis of the macroeconomic impact of the obesity epidemic on environmental degradation in the LAC region. Case studies combine theory and practice to achieve critical conclusions (and subsequent policy implications), providing useful tools for those working on actual health, energy and environmental challenges. Written for researchers, policymakers, international organizations and practitioners in various fields, especially those in public health, health economics, energy and environmental economics and social sciences, this book thoroughly highlights the obesity epidemic in this region. In the LAC region, obesity has become a public health issue. The increase of this problem is related to the economic gains obtained from the process of liberalization and privatization, the increase of foreign investment, and infrastructure investments.