Bøger udgivet af Elsevier Science & Technology

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications-arrhythmias, heart failure, and even death.

Customized Ob/Gyn Management for Diverse Populations provides tailored options of management for optimal clinical care of the major preventive and interventive Ob/Gyn issues. Case scenarios highlight and discuss the need for customized care and inclusive protocols that depend on each woman's race, gender, sexual orientation, culture and socio-economic factors. As health disparities adversely affect groups of people who have systematically experienced greater social and economic obstacles to health based on their racial or ethnic group, socioeconomic status, gender, sexual orientation or other characteristics historically linked to discrimination or exclusion, this book provides a welcomed resource.The book highlights the fact that in order to change the current scenario the health care community needs more information and awareness of health care data regarding diverse groups, population health and well-being.

Autophagy Processes and Mechanisms details the process of autophagy and its significance in diseases and aging. It provides insights into autophagy mechanisms and processes to broaden our understanding. By collecting recent progress on several aspects of the autophagy process, it provides a more integrative perspective and serves as a resource that can influence future research initiatives in the field. This new book is appropriate for basic and applied researchers in cell biology, biologists and those working in the pharmaceutical sciences.

Probiotics for Human Nutrition in Health and Disease provides a comprehensive resource of information on traditional and emerging health concepts and the development and application evolution of probiotics and their role in prevention and treatment of human metabolic disorders and illnesses. Key issues related to the general aspects of probiotics, probiotics in human nutrition, and probiotics in human health promotion and disease treatment are described and discussed. Sections discuss general features of probiotics, such as relationships with prebiotics, probiotics in human nutrition, including pregnancy, lactation, in children, and in the elderly, and the role of probiotics in human health and disease treatment. This book provides the most significant knowledge, mechanistic bases, uses, clinical perceptions, case studies and perspectives about probiotics for humans, considering possibilities and limitations in light of the appropriate available reference materials. Written by highly qualified researchers and edited by a team of experts, each chapter summarizes the latest available information on probiotics in human health and critically interprets the most significant evidence by applying the author''s own practical experience from investigations with probiotics. Present traditional and emerging concepts, developments and the evolution of probiotics Provides key insights that characterize probiotics as promising and innovative options for human nutrition Discusses how probiotics can be used in a perspective of health promotion and prevention and treatment of human metabolic disorders and illnesses

Autophagy Dysfunction in Alzheimer's Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer's. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer's and other neurodegenerative diseases.

Exercise to Prevent and Manage Chronic Disease Across the Lifespan provides evidence-based insights into the clinical utility of exercise in the management of disease across a broad range of specialties and diseases. The book offers research informed strategies for the integration of exercise into standard practice in fields such as neurology, endocrinology, psychiatry and oncology, as well as decision-making pathways and clinical scenarios to advance patient care. The book is divided by specialty and includes clinical scenarios to allow for the integration of information within practice. The book's synthesized research evidence allows practitioners to safely and effectively begin to capitalize on the benefits of exercise in their patients.

Advances of Artificial Intelligence in a Green Energy Environment reviews the new technologies in intelligent computing and AI that are reducing the dimension of data coverage worldwide. This handbook describes intelligent optimization algorithms that can be applied in various branches of energy engineering where uncertainty is a major concern. Including AI methodologies and applying advanced evolutionary algorithms to real-world application problems for everyday life applications, this book considers distributed energy systems, hybrid renewable energy systems using AI methods, and new opportunities in blockchain technology in smart energy. Covering state-of-the-art developments in a fast-moving technology, this reference is useful for engineering students and researchers interested and working in the AI industry. Looks at new techniques in artificial intelligence (AI) reducing the dimension of data coverage worldwide Chapters include AI methodologies using enhanced hybrid swarm-based optimization algorithms Includes flowchart diagrams for exampling optimizing techniques

Clinical PET/MR presents the state-of-the-art of PET/MR, guiding the reader from how to scan patients, how to read and report the studies, and how keep an eye on what is clinically relevant for a patient¿s care. Each chapter starts with the clinical scenario and then moves to pertinent imaging, addressing the need of a clinical PET/MR book written by world experts in both clinical and imaging fields. It discusses the clinical application of PET/MR in diverse subspecialties such as head and neck, neurology, cardiovascular, pediatrics, chest, bone, hematology, breast, hepatobiliary pancreatic, genitourinary, gynecology, and gastrointestinal tract. This book is a valuable resource for radiologists, oncologists and members of the biomedical field who need to learn more about clinical applications of PET/MR.

Advanced Methods in Biomedical Signal Processing and Analysis presents state-of-the-art methods in biosignal processing, including recurrence quantification analysis, heart rate variability, analysis of the RRI time-series signals, joint time-frequency analyses, wavelet transforms and wavelet packet decomposition, empirical mode decomposition, modeling of biosignals, Gabor Transform, empirical mode decomposition. The book also gives an understanding of feature extraction, feature ranking, and feature selection methods, while also demonstrating how to apply artificial intelligence and machine learning to biosignal techniques. Gives advanced methods in signal processing Includes machine and deep learning methods Presents experimental case studies

Internet of Multimedia Things (IoMT): Techniques and Applications disseminates research efforts in the security and resilience of intelligent data-centric critical systems to support advanced research in this area. Sections cover the background of IoMT Architectures and Technologies, describe the problems that arise in IoMT Computing and protocols, and illustrate the application of IoMT on Industrial applications. The book will be beneficial for engineers, developers, solution designers, architects, system engineers and specialists from professional environments interested in the IoMT to seek appropriate solutions to their specific problems. Addresses recent developments, along with relevant prospects on opportunities and challenges in IoMT Presents the concept and vision of the IoMT, whose potentialities are discussed with speci?c use-cases Discusses the distinct architectural design and characteristics of IoMT as compared to the existing multimedia systems

Advances in Legume-based Agroecoystem for Sustainable Intensification explores current research and future strategies for ensuring capacity growth and socioeconomic improvement through the utilization of legume crop cultivation and production in the achievement of sustainability development goals (SDGs). Sections cover the role of legumes in addressing issues of food security, improving nitrogen in the environment, environmental sustainability, economic-environmentally optimized systems, the importance and impact of nitrogen, organic production, and biomass potential, legume production, biology, breeding improvement, cropping systems, and the use of legumes for eco-friendly weed management. This book is an important resource for scientists, researchers and advanced students interested in championing the effective utilization of legumes for agronomic and ecological benefit. Focuses on opportunities for agricultural impact and sustainability Presents insights into both agricultural sustainability and eco-intensification Includes the impact of legume production on societal impacts such as health and wealth management

Food Preservation and Safety of Natural Products addresses the most common causes of food spoilage that create significant loss to global food production while also discussing how food serves as a vehicle for the transmission of pathogenic microorganisms responsible for mild to debilitating health conditions in humans. The book provides essential information for food safety professionals on issues relating to foodborne diseases and offers potential solutions by presenting various methods of incorporating natural products in food production to prevent the spread of foodborne pathogenic organisms. The demand for green consumerism and consumers general distaste for synthetic food additives poses a serious challenge to food safety and preservation. Natural products are used as green and sustainable source of bioactive compounds that can be applied in various fields including food. The use of plant and other natural products in food preservation is on the rise, hence this book reviews microbial mediated food spoilage, foodborne pathogens and food contamination and offers applications of natural products in food preservation. Provides important information on microbial metabolic by-products (natural enzymatic processes) to prevent food spoilage or deterioration Includes molecular techniques for antimicrobial and antioxidant applications in food, food packaging and edible films Presents the latest evidence-based science on the natural products used as additives in food

Advanced Mathematical Modelling of Biofilms and its Applications covers the concepts and fundamentals of biofilms, including sections on numerical discrete and numerical continuum models and different biofilms methods, e.g., the lattice Boltzmann method (LBM) and cellular automata (CA) and integrated LBM and individual-based model (iBM). Other sections focus on design, problem-solving and state-of-the-art modelling methods. Addressing the needs to upgrade and update information and knowledge for students, researchers and engineers on biofilms in health care, medicine, food, aquaculture and industry, this book also covers areas of uncertainty and future needs for advancing the use of biofilm models. Over the past 25-30 years, there have been rapid advances in various areas of computer technologies, applications and methods (e.g. complex programming and algorithms, lattice Boltzmann method, high resolution visualization and high-performance computation). These new and emerging technologies are providing unprecedented opportunities to develop modeling frameworks of biofilms and their applications.

Human-Centered Artificial Intelligence: Research and Applications presents current theories, fundamentals, techniques and diverse applications of human-centered AI. Sections address the question, "are AI models explainable, interpretable and understandable?, introduce readers to the design and development process, including mind perception and human interfaces, explore various applications of human-centered AI, including human-robot interaction, healthcare and decision-making, and more. As human-centered AI aims to push the boundaries of previously limited AI solutions to bridge the gap between machine and human, this book is an ideal update on the latest advances. Presents extensive research on human-centered AI technology Provides different methods and techniques used to investigate human-AI interaction Discusses open questions and challenges in trust within human-centered AI Explores how human-centered AI changes and operates in human-machine interactions

Professional Development, Training, and Supervision in Human Services Organizations provides the latest research on Human Service Organizations (HSO) groups, both public and private, and their use of the Organizational Behavior Management (OBM) model for effective designing, implementing and maintaining services within HSOs. Each volume in this series highlights key concepts and applications pertinent to each division of HSOs, with this release providing program directors and supervisors with the tools they need to develop an efficient and effective training program for onboarding, performance evaluation and professional development for their staff. Provides detailed content and components for delivering orientation and new-hire training Demonstrates how to use function-based assessments during evaluations Highlights various on-the-job training techniques for clinical programs, including shadow training and knowledge quizzes Details steps for continuous professional development, including certification and participation in scholarly activities

Solar Receivers for Thermal Power Generation: Fundamentals and Advanced Concepts looks at different Concentrated Solar Power (CSP) systems, their varying components, and the modeling and optimization of solar receivers. The book combines the detailed theory of receivers, all physical concepts in the process of converting solar radiation into electricity in CSP systems, and the main components of CSP systems, including solar concentrators, thermal receivers and power blocks. Main properties and working principles are addressed, along with the principles of solar resources and energy output of CSP systems and solar radiation. By covering different types and designs of solar receivers, heat transfer fluids, operating temperatures, and different techniques used in modeling and optimizing solar receivers, this book is targeted at academics engaged in sustainable energy engineering research and students specializing in power plant solarization. Features methods of modeling the thermal performance of different solar receivers Provides step-by-step linchpins to advanced theory and practice Includes global case studies surrounding progress in the development of solar receivers

Robotic Cell Manipulation introduces up-to-date research to realize this new theme of medical robotics. The book is organized in three levels: operation tools (e.g., optical tweezers, microneedles, dielectrophoresis, electromagnetic devices, and microfluidic chips), manipulation types (e.g., microinjection, transportation, rotation fusion, adhesion, separation, etc.), and potential medical applications (e.g., micro-surgery, biopsy, gene editing, cancer treatment, cell-cell interactions, etc.). The technology involves different fields such as robotics, automation, imaging, microfluidics, mechanics, materials, biology and medical sciences. The book provides systematic knowledge on the subject, covering a wide range of basic concepts, theories, methodology, experiments, case studies and potential medical applications. It will enable readers to promptly conduct a systematic review of research and become an essential reference for many new and experienced researchers entering this unique field. Introduces the applications of robot-assisted manipulation tools in various cell manipulation tasks Defines many essential concepts in association with the robotic cell manipulation field, including manipulation strategy and manipulation types Introduces basic concepts and knowledge on various manipulation devices and tasks Describes some cutting-edge cell manipulation technologies and case studies

Computational Intelligence in Cancer Diagnosis: Progress and Challenges provides insights into the current strength and weaknesses of different applications and research findings on computational intelligence in cancer research. The book improves the exchange of ideas and coherence among various computational intelligence methods and enhances the relevance and exploitation of application areas for both experienced and novice end-users. Topics discussed include neural networks, fuzzy logic, connectionist systems, genetic algorithms, evolutionary computation, cellular automata, self-organizing systems, soft computing, fuzzy systems, and hybrid intelligent systems. The book's chapters are written by international experts from both cancer research, oncology and computational sides to cover different aspects and make it comprehensible for readers with no background on informatics.

Covid-19: Biomedical Perspectives, Volume 50 in the Methods in Microbiology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Individual chapters in this new release include Sensitive methods for detection of SARS-CoV-2 RNA, Treatment of COVID-19 using Chinese herbal medicine, Understanding how SARS-CoV-2 is evolving and its impact on COVID-19 animal models and vaccine evaluation, Methods in machine learning to identify COVID-19 literature, COVID-19 seasonal behavior and the mutational landscape of the SARS-CoV-2 virus, CRISPR use in Diagnosis and Therapy for COVID-19, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods of Microbiology serials Updated release includes the latest information on Covid-19: Biomedical Perspectives

Forest Microbiology, Volume Two: Forest Tree Health highlights a range of emerging microbial phytopathogens of forest trees, along with novel approaches for managing tree pests and diseases in a changing climate. The book provides an overview of selected microbial pathogens of forest trees, with an emphasis on their biology, lifecycle, spreading mechanisms, impact on affected tree species and current and prospective control strategies. At the same time, the impact of tree microbiomes on host fitness is discussed. Beneficial components of tree microbiota are presented, along with their functional role in tree nutrition, immunity and disease resistance. In addition, this volume addresses the many functions of microbial disease agents of trees including fungi, bacteria, viruses and phytoplasma. Strong emphasis is placed on the genetics, biochemistry, physiology, evolutionary biology and population dynamics of the microorganisms involved. This title is a key resource for foresters and forest pathology practitioners, as well as plant biologists.

Petroleum engineers search through endless sources to understand oil and gas chemicals, find problems, and discover solutions while operations are becoming more unconventional and driving towards more sustainable practices.?The Oil and Gas Chemistry Management Series?brings an all-inclusive suite of tools to cover all the sectors of oil and gas chemicals from drilling to production, processing, storage, and transportation. The?second?reference in?the series,?Flow Assurance,?delivers the critical chemical oilfield basics while also covering latest research developments and practical solutions. Organized by the type of problems and mitigation methods, this reference allows the engineer to fully understand how to effectively control chemistry issues, make sound decisions, and mitigate challenges ahead. Basics include?root cause, model prediction and laboratory simulation of the major chemistry related challenges during oil and gas productions, while more advanced discussions cover?the chemical and non-chemical mitigation strategies for more efficient, safe and sustainable operations. Supported by a list of contributing experts from both academia and industry,?Flow Assurance?brings a necessary reference to bridge petroleum chemistry operations from theory into safer and cost-effective practical applications.? Offers?full?range of oilfield production chemistry issues, including chapters focused on?hydrate and organic deposition control, liquid blockage mitigation, and abiotic and microbially influenced corrosion prevention Gain effective control?on?problems and mitigation strategies from industry list of experts and contributors? Delivers both up to date research developments and practical applications, bridging between theory and practice

Mechanics of Offshore Pipelines, Second Edition, Volume One: Buckling and Collapse gives engineers fundamental knowledge on principles surrounding the mechanical behavior of pipelines and long tubular structures in the oil and gas industry. Addressing common challenges pertaining to buckling and collapse under various offshore loads, the authors go through each challenge experimentally, with supporting and analyzing data to present the main limits encountered. Helpful to both the practicing engineer and the graduate level, the combined effort of analysis supplemented with numerical modeling helps engineers design procedures and guidelines to reproduce the best solution or solve problems using a nonlinear finite element code. Custom formulations are also included to help users gain a deeper understanding of each challenge. Rounding out with helpful appendices, including a glossary of terms, this book continues to deliver critical research and data to engineers that need to design, install and maintain efficient and safe offshore pipelines.

Coral Reef Conservation, Volume 84 in the Advances in Marine Biology series, presents in-depth and up-to-date reviews on all aspects of marine biology. Published since 1963, this serial updates on a variety of topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Reviews articles on the latest advances in marine biologyAuthored by leading figures in their respective fields of studyPresents material that is widely used by managers, students and academic professionals in the marine sciences

Artificial Intelligence-Based Brain Computer Interface provides concepts of AI for modelling of non-invasive modalities of medical signals such as EEG, MRI, and FMRI. These modalities and their AI-based analysis are employed in BCI and related applications. This can help to improve the healthcare system through detection, identification, predication, analysis and classification of disease, management of chronic conditions, and delivery of health services. Artificial Intelligence-Based Brain Computer Interface emphasizes the real challenges in non-invasive input due to the complex nature of the human brain and for a variety of applications for analysis, classification and identification of different mental states. Each chapter starts with a description of a non-invasive input example and the need and motivation of the associated AI methods, along with discussions to connect the technology through BCI. Major topics include different AI methods/techniques such as Deep Neural Networks and Machine Learning algorithms for different non-invasive modalities such as EEG, MRI, FMRI for improving the diagnosis and prognosis of numerous disorders of the nervous system, cardiovascular system, musculoskeletal system, respiratory system and various organs of the body. The book also covers applications of AI in management of chronic condition, databases and delivery of health services. Various brain image modalities are analyzed and capabilities of the human brain will be exploited in BCI applications and case studies. The book presents AI methods for solving real-world problems and challenges in BCI and healthcare systems with the help of appropriate case studies and research results. Provides readers with an understanding of the key applications of Artificial Intelligence to Brain-Computer Interface for acquisition and modelling of non-invasive biomedical signal and image modalities for various conditions and disorders Integrates recent advancements of Artificial Intelligence to the evaluation of large amounts of clinical data for early detection of disorders such as Epilepsy, Alcoholism, Sleep Apnea, motor-imagery tasks classification, and others Provides readers with illustrative examples of how Artificial Intelligence can be applied to Brain-Computer Interface, including a wide range of case studies in predicting and classification of neurological disorders

Covers a range of conceptual, epistemological and methodological issues in the philosophy of science raised by reflection upon medical science and practice. This title includes chapters that examine such general meta-scientific concepts as discovery, reduction, theories and models, causal inference and scientific realism.

Provides an overview of both solvent extraction separation techniques and the competitive complexation/solvation theory. This book provides a key for a preliminary quantitative prediction of suitable extraction systems without experimentation, thus saving researchers time and resources. It analyzes classical and competitive models and techniques.

Presents a symbiosis of a brief description of physical fundamentals of rock properties (based on typical experimental results and relevant theories and models) with a guide for practical use of different theoretical concepts. This title also presents the problem of relationships between petrophysical parameters based on various model concepts.