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This book is useful for physicians taking care of patients with cardiac arrhythmias and includes six chapters written by experts in their field. Chapter 1 discusses basic mechanisms of cardiac arrhythmias. Chapter 2 discusses the chronobiological aspects of the impact of apnoic episodes on ventricular arrhythmias. Chapter 3 discusses navigation, detection, and tracking during cardiac ablation interventions. Chapter 4 discusses epidemiology and pathophysiology of ventricular arrhythmias in several noncardiac diseases, methods used to assess arrhythmia risk, and their association with long-term outcomes. Chapter 5 discusses the treatment of ventricular arrhythmias including indications for implantation of an AICD for primary and for secondary prevention in patients with and without congestive heart failure. Chapter 6 discusses surgical management of atrial fibrillation.
The reconciliation of economic development, social justice and reduction of greenhouse gas emissions is one of the biggest political challenges of the moment. Strategies for mitigating CO2 emissions on a large scale using sequestration, storage and carbon technologies are priorities on the agendas of research centres and governments. Research on carbon sequestration is the path to solving major sustainability problems of this century a complex issue that requires a scientific approach and multidisciplinary and interdisciplinary technology, plus a collaborative policy among nations. Thus, this challenge makes this book an important source of information for researchers, policymakers and anyone with an inquiring mind on this subject.
The edited book Pesticides - Toxic Aspects contains an overview of attractive researchers of pesticide toxicology that covers the hazardous effects of common chemical pesticide agents employed every day in our agricultural practices. The combination of experimental and theoretical pesticide investigations of current interest will make this book of significance to researchers, scientists, engineers, and graduate students who make use of those different investigations to understand the toxic aspects of pesticides. We hope that this book will continue to meet the expectations and needs of all interested in different aspects of pesticide toxicity.
This book is a collection of chapters dealing with examples of RNA and DNA viruses, and issues such as how these gene packages have learnt to take advantage of their hosts, molecular recognition events that hosts may use to counterattack the viruses, and how researchers have developed strategies to use viruses or their parts as tools for different purposes.
This book emphasis on multi-user MIMO communication. It covers a collection of the major topics and issues in multi-user MIMO systems. Recent Trends in Multi-user MIMO Communications provides a tutorial overview of the latest technologies and research keys related to multi-user communication.This book is composed of seven chapters, each written by a different set of authors. Features include: Fundamentals of multi-user MIMO communication, Random Beamforming in multi-user MIMO systems, LTE and LTE-Advanced framework, Interference cancellation in multi-user MIMO systems, Incorporation of multi-user capabilities in IEEE 802.11n/ac for WLAN systems, Physical layer security for multi-user MIMO communication, User selection based error probability of MIMO detector in multi-user MIMO systems.
The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues, such as combining functional MRI technology with other brain imaging modalities. The second section examines the application of brain neuroimaging to understand cognitive, visual, auditory, motor and decision-making networks, as well as neurological diseases. The use of non-invasive neuroimaging technologies will continue to stimulate an exponential growth in understanding basic brain processes, largely as a result of sustained advances in neuroimaging methods and applications.
Echocardiography is still the most used imaging technique for the evaluation of cardiac anatomy and function and today it plays an essential role in daily decision making.The echocardiographic technology and its applications have widely developed in the last years leading to a better diagnostic accuracy. On the other hand echocardiography specialists have new clinical questions to answer.Echocardiography meets the growing need for non-invasive imaging in the expanding heart failure population and during structural heart interventions. The new percutaneous therapies need, a precise evaluation of cardiac dimensions and a complete understanding of the spatial relationships between cardiac structures. Echocardiography is of paramount importance both during the patient evaluation and guiding the procedure.This book tries to give an in depth evaluation about the specific issues that a modern cardiovascular imaging specialist is asked to answer nowadays.
Bioremediation technologies are gaining immense credibility in the field of waste management because of their eco-compatibility nature. Biomass can interact and confront with water and soil pollutants in both active (live) as well as passive (dead) way, thereby offering numerous opportunities of exploring them for environmental clean-up. In 21st century, wastes are no longer a waste but are recognized as a valuable Resource. Employing novel and integrated strategies for the development of modern bioremediation processes is desperate need of the hour. This edited book on Applied Bioremediation - Active and Passive Approaches contains mix of interesting chapters that will certainly add to the advancement of knowledge and will provide the required valuable resource and stimulus to the researchers worldwide.
Hepatocellular carcinoma (HCC) develops as a consequence of underlying chronic liver disease, most commonly cirrhosis. Therefore, HCC management draws on the expertise of a range of medical specialists. Many components of current novel therapeutic modalities for HCC are discussed in the current version of the book within the framework of a multidisciplinary approach with special emphasis on emerging treatment approaches and research strategies. This book is the essential clinical guide for oncologists, hepatologists, surgeons, and all physicians and researchers involved in the care of patients with HCC. I would like to thank the authors for their significant efforts in bringing this edition to life. This book is a tribute to their continued dedication to improving HCC outcome.
Learn the recent statements concerning the impact and management of mother-fetal thrombophilia, the achievement necessary for gestation complication prevention and realizing a successful pregnancy valuation. Pregnancy Thrombophilia - The Unsuspected Risk encompasses complete many-sides aspects of thrombophilic conditions during pregnancy, including clinical and basic knowledge approach faced to: 1) Obstetricians, IVF involving gynecologists, Internists, and General practitioners, especially skilled in high risk pregnancy assessment will receive up to date evidence for mother thrombophilia testing indications, an incoming pharmacogenetic approach of individualized antithrombotic therapy and thrombotic tendency management in assisted reproductive technics; 2) Physicians, in particular geneticists, biologists and all researchers, who combine the science of the laboratory with teaching practice, will have essential benefits from the chapters of physiology, pathological and molecular basis of maternal/fetus thrombophilia; 3) The mother-health incorporated immunologists will find a new therapeutic approach beyond anticoagulant treatment in pregnancy with autoimmune conditions. Pregnancy Thrombophilia - The Unsuspected Risk gives you a chance to a rapid review of the recent stands, concerning maternal thrombotic state and authoritative and easy to read summary answers in your daily pregnancy follow up practice.
Our understanding of the pathology of amyotrophic lateral sclerosis is a continuously changing field. New hypotheses are generated with each new discovery; they are abandoned to be reanalyzed after some time under the light of new observations. This book present a series of reviews from experts in different aspects of the disease focus on these hypotheses. There are also a few review chapters providing clear examples of these new observations that make the field to reanalyze previous conclusions.
Muscle tears are one of the most common pathologies in sport and one of the most frequent causes of sport activity suspension. The purpose of this book is to review the state of the art of the actual knowledge on muscle tears in athletes, in particular for what concern the biology of muscle healing, the conservative and surgical treatments and the preventive aspects. Therefore, this textbook can be a valid tool for all Sport Medicine practitioners such as physicians, physiotherapists and fitness coaches.
Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.
Acoustics is a mature field which enjoys a never ending youth. New developments are induced by either the search for a better understanding, or by technological innovations. Micro-fabrication techniques introduced a whole new class of microdevices, which exploit acoustic waves for various tasks, and in particular for information processing and for sensing purposes. Performance improvements are achievable by better modelling tools, able to deal with more complex configurations, and by more refined techniques of fabrication and of integration in technological systems, like wireless communications. Several chapters of this book deal with modelling and fabrication techniques for microdevices, including unconventional phenomena and configurations. But this is far from exhausting the research lines in acoustics. Theoretical analyses and modelling techniques are presented, for phenomena ranging from the detection of cracks to the acoustics of the oceans. Measurement methods are also discussed, which probe by acoustic waves the properties of widely different systems.
This book is an overview of the complex and multifaceted topic of natural disasters impact. Several possible approaches can be undertaken to assess economic, psychological, societal or environmental damage caused by natural disasters, aiming to reduce the effects of future events on the whole of these sectors. This book proposes a range of studies realized in different continents, showing various aspects from which natural disasters can be view, thus giving a measure of the complexity and multidisciplinary of the topic. It starts with a paper presenting a possible strategy to either avoid or reduce the vulnerability of concrete buildings during floods. Then, it continues with an insight into the communication during post-disaster emergency phase and with two chapters concerning the assessment of two different kinds of impact on people everyday life. The book ends with an analysis of the role of stakeholder participation in post-disaster reconstruction.
Graphene is proving to be the magic material of the 21th century. It is widely accepted that it is the strongest material ever studied and can be an efficient substitute for silicon. Besides, fascinating properties of graphene, such as the highest electrical conductivity among the discovered substances, have dramatically shocked science and technology world. Graphene is a carbon based layer with high atomic density. Its extraordinary characteristics such as extremely high mechanical strength, hardness, and adjustable thermal and electrical conductivity, as well as excellent surface and optical feature through chemical marking, have received great deal of attention by many researchers. This book collects new advances of this interesting nanomaterial.
The idea of this book was born due to the rapid increase of the interest in excellence of agricultural production in the aspect of both - the quality of raw material for food production as well as in the aspect of environment protection. Agrophysics is a field of science that focuses on the quality of agriculture as a whole i.e. the interaction between human and environment, especially the interaction between soil, plant, atmosphere and machine. Physics with its laws, principles and rules is a good tool for description of the interactions, as well as of the results of these interactions. Some aspects of chemistry, biology and other fields of science are also taken under consideration. This interdisciplinary approach can result in holistic description of processes which should lead to improvement of the efficiency of obtaining the raw materials to ensure a sufficient amount of food, safe for human health. This book could be regarded as the contribution to this description. The reader can find some basic as well, as more particular aspects of the contemporary agriculture, starting with the soil characteristics and treatment, plant growth and agricultural products' properties and processing.
In an age of explosive worldwide growth of electronic data storage and communications, effective protection of information has become a critical requirement. When used in coordination with other tools for ensuring information security, cryptography in all of its applications, including data confidentiality, data integrity, and user authentication, is a most powerful tool for protecting information. This book presents a collection of research work in the field of cryptography. It discusses some of the critical challenges that are being faced by the current computing world and also describes some mechanisms to defend against these challenges. It is a valuable source of knowledge for researchers, engineers, graduate and doctoral students working in the field of cryptography. It will also be useful for faculty members of graduate schools and universities.
Advanced lithography grows up to several fields such as nano-lithography, micro electro-mechanical system (MEMS) and nano-phonics, etc. Nano-lithography reaches to 20 nm size in advanced electron device. Consequently, we have to study and develop true single nanometer size lithography. One of the solutions is to study a fusion of top down and bottom up technologies such as EB drawing and self-assembly with block copolymer. In MEMS and nano-photonics, 3 dimensional structures are needed to achieve some functions in the devices for the applications. Their formation are done by several methods such as colloid lithography, stereo-lithography, dry etching, sputtering, deposition, etc. This book covers a wide area regarding nano-lithography, nano structure and 3-dimensional structure, and introduces readers to the methods, methodology and its applications.
There has been a remarkable difference in the research and development regarding gas turbine technology for transportation and power generation. The former remains substantially florid and unaltered with respect to the past as the superiority of air-breathing engines compared to other technologies is by far immense. On the other hand, the world of gas turbines (GTs) for power generation is indeed characterized by completely different scenarios in so far as new challenges are coming up in the latest energy trends, where both a reduction in the use of carbon-based fuels and the raising up of renewables are becoming more and more important factors. While being considered a key technology for base-load operations for many years, modern stationary gas turbines are in fact facing the challenge to balance electricity from variable renewables with that from flexible conventional power plants. The book intends in fact to provide an updated picture as well as a perspective view of some of the abovementioned issues that characterize GT technology in the two different applications: aircraft propulsion and stationary power generation. Therefore, the target audience for it involves design, analyst, materials and maintenance engineers. Also manufacturers, researchers and scientists will benefit from the timely and accurate information provided in this volume. The book is organized into three main sections including 10 chapters overall: (i) Gas Turbine and Component Performance, (ii) Gas Turbine Combustion and (iii) Fault Detection in Systems and Materials.
Our knowledge of mass transfer processes has been extended and applied to various fields of science and engineering including industrial processes in recent years. Since mass transfer is primordial phenomenon, it plays a key role in the scientific researches and fields of mechanical, energy, environmental, materials, bio, and chemical engineering. In this book, energetic authors especially provide advances in scientific findings and technologies, and develop new theoretical models concerning mass transfer for sustainable energy and environment. This book brings valuable references for research engineers working in the variety of mass transfer sciences and related fields. Since the constitutive topics cover the advances in broad research areas, the topics will be mutually stimulus and informative not only to research engineers, but also to university professors and students.
The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic.P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
In June 2001, operators and equipment vendors in the communications ecosystem founded the nonprofit WiMAX Forum, an industry-led organization aimed at harmonizing broadband wireless access standards. Nowadays, about 10 years later, the WiMAX technology is a mature and affordable solution for high-speed IP-based 4G mobile broadband, fully supporting bandwidth-intensive services,such as high-speed Internet access and television, as well as less bandwidth-demanding but more latency-sensitive services, such as voice-over-IP calls.In this book a collection of selected papers is presented, which covers several aspects of the WiMAX technology, with particular reference to multiuser multiple input multiple output diversity techniques,peak-to-average power ratio, mesh architectures, handover mechanisms, coordinated authentication in a heterogeneous network environment and multicast /broadcast re-keying algorithms.
Ultrasonic imaging is a powerful diagnostic tool available to medical practitioners, engineers and researchers today. Due to the relative safety, and the non-invasive nature, ultrasonic imaging has become one of the most rapidly advancing technologies. These rapid advances are directly related to the parallel advancements in electronics, computing, and transducer technology together with sophisticated signal processing techniques. This book focuses on state of the art developments in ultrasonic imaging applications and underlying technologies presented by leading practitioners and researchers from many parts of the world.
This book contains a collection of different biodegradation research activities where biological processes take place.The book has two main sections: A) Polymers and Surfactants Biodegradation and B) Biodegradation: Microbial Behaviour.
This book contains a collection of different research activities that include the biodegradation compounds with contaminant characteristics and special products of different interests as an added value product or that allows following up various biological processes. The chapters consider the degradation of contaminant compounds generated by industrial activities, i.e., oil industry by-product compounds and halogen compounds or compound generated by natural phenomena such as tsunamis, which require interventions to recover damaged soils. In addition, the book contains chapters that involve special product degradation processes such as chlorophyll, which corresponds to a biological process indicator as photosynthesis.
This book contains a collection of different research activities where several technologies have been applied to the optimization of biodegradation processes. The book has three main sections: A) Hydrocarbons biodegradation, B) Biodegradation and anaerobic digestion, and C) Biodegradation and sustainability.
Molecular Toxinology has been consolidated as a scientific area focused on the intertwined description of several aspects of animal toxins. In an inquiring biotechnological world, animal toxins appear as an invaluable source for the discovery of therapeutic polypeptides. Animal toxins rely on specific chemical interactions with their partner molecule to exert their biological actions. The comprehension of how molecules interact and recognize their target is essential for the rational exploration of bioactive polypeptides as therapeutics. Investigation on the mechanism of molecular interaction and recognition offers a window of opportunity for the pharmaceutical industry and clinical medicine. Thus, this book brings examples of two interconnected themes - molecular recognition and toxinology concerning to the integration between analytical procedures and biomedical applications.
This book covers the latest developments in remote sensing theory and applications by numerous researchers, experts and collaborators of the Remote Sensing and Geo-Environment Lab of the Department of Civil Engineering and Geomatics of the Cyprus University of Technology. The main highlight of this book is combination of several techniques such as satellite remote sensing, field spectroscopy, smart sensors, ground techniques for achieving an integrated method for the systematic monitoring of the environment.
Surface engineering can be defined as an enabling technology used in a wide range of industrial activities. Surface engineering was founded by detecting surface features which destroy most of pieces, e.g. abrasion, corrosion, fatigue, and disruption; then it was recognized, more than ever, that most technological advancements are constrained with surface requirements. In a wide range of industry (such as gas and oil exploitation, mining, and manufacturing), the surfaces generate an important problem in technological advancement. Passing time shows us new interesting methods in surface engineering. These methods usually apply to enhance the surface properties, e.g. wear rate, fatigue, abrasion, and corrosion resistance. This book collects some of new methods in surface engineering.
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