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Most of the information on the functional role, structure and molecular biology of creatine kinase is scattered in several hundreds of publications. The editors of this volume invited authors who are most active at present in experimental research on creatine kinases to summarize their work and make the information easily available to a wider scientific audience, especially to young investigators who are entering this field. Since the functional role of coupled creatine kinases is directly related to the phenomenon of compartmentation and structural organization of metabolic networks, we also invited experts in the related areas to contribute to the volume.
This title details the essential roles that small telescopes should play in 21st century science and how their future productivity can be maximized. Over 70 experts from all corners of the international astronomical community have created a reference on the future of big science with small telescopes. at national facilities and their omission from national science priority studies, the oft-lamented demise of the small telescope has been greatly exaggerated. In fact, the future of these workhorses of astronomy will be brighter than ever if creative steps are taken now. This three-volume set defines essential roles that small telescopes should play in 21st century science and the ways in which a productive future for them can be realized. A wide cross-section of the astronomical community has contributed to a definitive assessment of the present and a vision for the future. radio- and space-based facilities face problems in scientific prioritization and funding. It highlights how current small facilities are evolving to meet the scientific priorities and economical realities of the 21st century through standardization of instrumentation, use of off-the-shelf technology, specialization, optical improvements, new modes of scheduling, automation, and internet access.
This volume contains contributions, written by specialists, which deal with various aspects of the structure and dynamics of non-rigid molecules. Together these papers provide an authoritative overview of research and progress in this field. The contents are divided into three sections which cover, respectively: fundamental questions in non-rigid molecular problems; the structure and symmetry of non-rigid molecular systems; and the dynamics of non-rigid molecular systems.
This volume brings together studies on the differences and profound similarities in the molecular mechanism of virulence between bacteria pathogenic for humans, animals and plants. Topics covered include: host cell recognition and binding, pathogen ingression and invasive mechanism, enzymes, toxins and other pathogenic factors, regulation of virulence genes and signal transduction, and pathogen of host-defence mechanisms.
A practical approach to problems commonly encountered in paediatric tumour diagnosis. It comprehensively covers a wide range of common and unusual entities. Over 300 full-colour illustrations are complemented by a text which is pragmatic and succinct. References have been carefully selected to reflect current thought and well-written reviews.
This book deals with the most important areas of the Earth's plasma environment - the polar cap boundaries, the discussion focusing on the key role played by the polar cap and its boundaries in magnetospheric-ionospheric science on both the day and night sides. identification criteria have been compiled for the magnetospheric boundary layers that are of central importance to current research and to applications in space weather activities. The book includes a number of linked themes in solar-terrestrial physics, such as the bow shock, the magnetosheath and the magnetopause; and how the interplanetary magnetic field orientation and the solar wind control the structure and the dynamics of dayside cusp and cleft regions.
Proceedings of the December 1993 title conference held in Research Triangle Park, North Carolina, presenting research on nutritional factors in coronary heart disease and cancer. Topics include the role of lipoproteins in atherogenesis, the impact of biotechnology in diagnosis and therapeutic manage
Magnetic resonance is a safe, non-invasive technique which can be used to produce high resolution, thin tomographic slices in any chosen plane, or true three-dimensional blocks of information. It has become the method of choice for studying the central nervous system, the vertebral column and many joints, but has not yet gained general acceptance in the cardiovascular system, although there are techniques for overcoming the problems of cardiac movement to produce excellent cardiovascular images.
Are there other planetary systems like ours? Other planets like ours? Is there life elsewhere in the Universe? So asks Dr. Lew Allen Jr. in the foreword. In December of 1992, theorists, observers, and instrument builders gathered at the California Institute of Technology to discuss the search for answers to these questions.
The Acid Reign '95? Conference in Goteborg, Sweden, 26-30 June 1995, was the fifth such conference in the series starting in Columbus, Ohio, in 1975 and including Sandefjord, Norway, in 1980, Muskoka, Canada in 1985, and Glasgow, Scotland, in 1990. Approximately 420 of the presentations at the conference appear in this volume. The papers are divided into 20 different topics, each topic representing an important aspect of the acidification phenomenon. The papers appear in four books, this volume contains the plenary talks and the other three the remaining scientific papers.
These two volumes comprise 40 papers coming from the most outstanding contributions to the third European Quantum Systems in Chemistry and Physics Workshop held in Granada, Spain (1997). These books cover a very broad spectrum of scientific research work from quantum-mechanical many-body methods to important applications and computational developments, and from atoms and molecules to condensed matter.
This volume is a record of the proceedings of the IXth International Rotifer Symposium, which was held in Khon Kaen, Thailand, on January 16-23, 2000. It contains reviews and research papers dealing with diverse aspects of scientific research related to Rotifera and their ecology. Some of the topics addressed are: taxonomy and zoogeography, ecology, phylogeny and evolution, physiology, biochemistry and population genetics, aquaculture, and ecotoxicology. This book contains a compilation of contemporary rotifer-related research, and is the eighth of a series of rotifer symposium proceedings published in Developments of Hydrobiology. This update of Rotifera studies should be of great interest to invertebrate zoologists, hydrobiologists, ecologists, and aquaculturists, particularly those interested in freshwater habitats.
Chromatography and all the related separation techniques are experimental in their origin and justification. However, the spectacular progress made in this area since World War II has given rise to a theoretical underpinning. The present book covers the current status of the research area and places it in perspective with the general concepts of the fields of physical chemistry involved.
Since the publication of the first edition of this book in 1983, A Handbook for Medical Teachers has established itself as a resource for both new and established teachers in an area where there is very little other support. It combines basic educational principles with a how-to approach in a readable way, supported by numerous illustrations and cartoons.
This comprehensive book, illustrated with over 700 colour pictures, addresses the subject of bone in internal medicine. It is based on biopsies of bone and first describes the normal range of physiological findings in iliac crest biopsies in young, middle-aged and elderly individuals.
The proceedings of a February 1994 conference in New South Wales comprise 13 papers reporting some recent basic research results on neurotransmitters in the brain and how they may contribute to the understanding of such diseases as Alzheimer's, Parkinson's, Huntington's, depression, and schizophreni
This text deals specifically with the procedures used in the analysis of structural relationships and the determination of structural successions in complexly deformed rocks such as migmatites and gneisses.
Male urogenital glands (also named male accessory sex glands) have received relatively little attention from electron microscopists, with the possible exception of the prostate gland. Moreover, even though comparative studies have clearly shown that these glands exhibit species-dependent features, very few studies, scattered over various publications, are available on the urogenital glands of man.
Needle biopsy of the liver is now an accepted procedure in most large hospitals, and surgeons and laparoscopists are more likely to biopsy the liver under direct vision than in the past. Consequently, increasing demands are being made on pathologists for rapid diagnosis.
Crystal structure information and computational techniques are increasingly used in the design and development of a wide range of materials. These activities now encompass a broad chemical spectrum, reflected in the contributions published here, which cover: modern crystallographic techniques, databases and knowledge bases of experimental results, computational techniques and their interplay with experimental information, hydrogen bonding and other intermolecular interactions, supramolecular assembly and crystal structure prediction, and practical examples of materials design.
This work examines the idea of phenomenology throughout the different stages of Wittgenstein's philosophical development. It argues that Wittgenstein's entire philosophical life was mainly concerned with what is immediately given in one's experience. Early interpretations of the phenomenological elements in Wittgenstein's philosophy usually emphasized the unique nature of his later work. However, the author here makes the case that Wittgenstein's concern with immediate experience and the way we describe it guided his philosophical journey through the phenomenological problems that pervade his work.
This book is a comprehensive collection of papers presented at the International Symposium on Applied Theoretical Chemistry, held in Havana, Cuba in 1990. The text consists of updated and refereed versions of the main lectures delivered at the conference. Subjects include modern applications of theoretical chemistry in surface sciences, reactivity, molecular structures and properties and inverse spectroscopy.
The present volume and its companion, Boron in Soil and Plants: Reviews, contain details of late-20th century advances in boron nutrition. They are designed as references for researchers, university lecturers and graduate students. There is also sufficient practical information on the use of boron in agriculture, forestry and horticulture for advisers and fertilizer representatives to find these volumes valuable references.
This color atlas details the macroscopic and microscopic findings possible within synovial fluid and explains their diagnostic significance. A discussion of joints, joint structure, joint disease, and normal synovial fluid is followed by a section on technical aspects of synovial fluid examination.
This manual provides general information about molecular techniques relevant to molecular ecological research. Attention is paid to the use of molecular methods for studying the fate of genetically modified and native microorganisms in the environment.
Concentrations of pollutants in the atmosphere have increased dramatically over the last century and many of these changes are attributable to anthropogenic activities. The influence of acid rain has been well studied, but there has been no extensive exploration of other pollutants, such as toxic chemicals, heavy metals and radionuclides. Natural ecosystems, especially forests, tend to accumulate many of these pollutants which subsequently can affect ecosystem health. These contaminants may be very damaging to the environment in Eastern Europe, where the rapid disappearance of forest is the result not only of contamination but also of poor forest management practices. This book provides a study of this complex subject.
Genomic instability is a major threat to living organisms. To counteract the damaging effects posed by endogenous and environmental agents, such as chemicals or radiation, micro-organisms devote several percent of their genome to encode proteins that function in the repair and recombination of DNA. For many years, a relatively small group of scientists have carefully delineated the molecular mechanisms of these repair processes, using the simplest model systems available, namely Escherichia coli and Saccharomyces cerevisiae. These studies, which until recently had only moderate impact outside of the field, now provide the cornerstone for exciting new research into analogous processes in human cells. The reason for this is the revelation that the biochemical pathways for the accurate replication, repair and recombination of DNA have been conserved through evolution.
This text is an up-to-date review of current knowledge in the field of multiple drug resistance in human cancer. The literature up to the middle of 1993 is surveyed in specialist chapters written by different experts.
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