Bøger udgivet af Springer International Publishing AG

This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents.Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use.Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.

This text is a companion volume to Transmission Electron Microscopy: A Textbook for Materials Science by Williams and Carter. The aim is to extend the discussion of certain topics that are either rapidly changing at this time or that would benefit from more detailed discussion than space allowed in the primary text. World-renowned researchers have contributed chapters in their area of expertise, and the editors have carefully prepared these chapters to provide a uniform tone and treatment for this exciting material. The book features an unparalleled collection of color figures showcasing the quality and variety of chemical data that can be obtained from today¿s instruments, as well as key pitfalls to avoid. As with the previous TEM text, each chapter contains two sets of questions, one for self assessment and a second more suitable for homework assignments. Throughout the book, the style follows that of Williams & Carter even when the subject matter becomes challenging¿the aim is always to make the topic understandable by first-year graduate students and others who are working in the field of Materials ScienceTopics covered include sources, in-situ experiments, electron diffraction, Digital Micrograph, waves and holography, focal-series reconstruction and direct methods, STEM and tomography, energy-filtered TEM (EFTEM) imaging, and spectrum imaging. The range and depth of material makes this companion volume essential reading for the budding microscopist and a key reference for practicing researchers using these and related techniques.

The core aspects of modern complex system sciences are presented in the first chapters, covering network theory, dynamical systems, bifurcation and catastrophe theory, chaos and adaptive processes, together with the principle of self-organization in reaction-diffusion systems and social animals.

The course provides fundamental definitions of radiative processes and serves as a brief introduction to Bremsstrahlung and black body emission, relativistic beaming, synchrotron emission and absorption, Compton scattering, synchrotron self-compton emission, pair creation and emission.

sections in the books on Writing,Presentations, Correspondence and Interacting on Campus. Adrian Wallwork has written over 30 books covering General English (Cambridge University Press, Scholastic), Business English (Oxford University Press), and Scientific English (Springer).

Numerous thinkers have considered the Principle of Non-Contradiction, but none has clearly identified its inherent limitation: that it is itself only a formal principle.This book shows that negation plays a fundamental role both in the constitution of the principle and in the affirmation of its value, which consists in its undeniability. Since it is a formal negation, it is extrinsic to the negated in such a way that it is configured as a negation only insofar as it is applied to something.On the basis of this analysis, it is shown that it is possible to reverse the usual philosophical perspective: it makes no sense to speak of proof of the principle, but only of proof by virtue of the principle.This book is essential reading for all scholars and researchers of theoretical philosophy and Aristotle.

This brief explores the justification of the death penalty, using the 2018 Marjorie Stoneman Douglas High School shooting in Parkland, Florida, as a case study. The authors argue that when an offender¿s impairments severely impact their ability to make rational decisions, the death penalty is unjustified, regardless of the crime's severity. The book examines the case of Nikolas Cruz, the school shooter diagnosed with fetal alcohol spectrum disorder (FASD), including: The nature of FASD, how it was measured, and how it manifested in Cruz. The impact of FASD on Cruz¿s adaptive functioning. The concept of ¿psychiatric overshadowing¿ and how it led to the oversight of Cruz¿s FASD and associated brain damage by many mental health experts. The broader implications of FASD, with a recommendation to expand death penalty exemptions to include disorders equivalent to intellectual disabilities (ID).By focusing on the highly controversial Cruz case, the authors¿key experts from the trial¿offer insights into FASD and its often-overlooked role in determining criminal responsibility and sentencing. This book is essential for forensic psychologists, psychiatrists, mental health professionals, FASD/DD specialists, researchers, and legal professionals involved in death penalty defense work.

Intending to fill an important gap in medical training, this book presents an easy-to-learn, standardized approach to having compassionate and collaborative goals of careconversations with patients and families, a skill that can be difficult for clinicians to learn and that is not part of standard medical education curricula.Developed by a Palliative Care provider, this is the first book to teach everything clinicians need to know to gently guide patients and families through what can often bedifficult discussions about illness, disease, end-of-life wishes, and hospice care. This technique can be used to discuss any medical diagnosis or treatment, be employed atany age or stage of an illness, and can be used by health care professionals at any level.Readers will be introduced to the patterns of decline patients follow toward the end of life, criteria for recognizing when a patient's time is limited, hospice care, groundrules for compassionate communication, and a step-wise method of leading patients and families through difficult goals of care conversations in a collaborative way. Thebook includes specific questions to ask and starter language clinicians can use for developing their own patient-friendly talking points about disease progression, the endof life, concerns that a patient's time is limited, advanced directives, code status, and hospice care. An Arc of Conversation Guide, for use when learning this technique, is also included. While modern medicine is terrific at acute stabilization of illness or injury, it often ignores the elephant in the room-disease progression and death. By doing so, the healthcare system frequently misses opportunities to align patient wishes with the care they receive. Furthermore, physicians often avoid difficult conversations with patients due to a lack of training or the assumption that hospice care represents medical or personal failure. Incorporating the material and technique taught in The Arc of Conversation into everyday practice will enable clinicians to acknowledge and discuss patient decline and to confidently include hospice care as a viable option for treatment that can support patient values, wishes, and priorities. Moving toward a continually collaborative approach with patients-a shift away from physician-directed care to patient-centered care-will enable clinicians to develop treatment plans that prioritize outcomes that matter most to patients and families, improving patient and family experience of health care across their lives and providing patients with the 'soft landing' they want at the end.

This book uniquely operationalizes "sustainable ageing" as a concept for reimagining ways by which: (1) social and health threats (i.e., climate change events, extreme industrialization, infectious disease outbreak, and war) can constrain the implementation of healthy ageing campaigns or limit their outcomes, and (2) potential transdisciplinary strategies can be rolled out to optimize healthy ageing through the campaigns in contexts experiencing the threats.The United Nations Decade of Healthy Ageing 2021-2030 initiative drives major healthy ageing campaigns and encapsulates 10 initiatives for enabling people to maintain health as they age. Worsening social and health threats are, however, hindering the implementation of the campaigns. Consequently, healthy ageing may not be achieved or sustained, even in age-friendly contexts experiencing crises.Scholars agree these threats will adversely impact public health and an inclusive multidisciplinary approach to healthy ageing is necessary amidst the threats. This book provides an understanding of how healthy ageing should be framed and approached through the campaigns in a world experiencing crises. Among the topics covered are: Psychology of ¿Ageing in Place¿ Amidst Health and Social Threats: Perspectives on the Decade of Healthy Ageing Climate Change Adaptation for Healthy Ageing Research-Practice Gap: Impact on Campaigns and Mitigation Strategies Human Development Pathways for Empowering Older Adults: A Decade of Healthy Ageing Perspective Initiatives to Fight Ageism, Neglect, and Elderly Abuse During Crises: A Healthy Ageing PerspectiveSustainable Ageing: Reimagining Healthy Ageing Through the Lens of Flagship Campaigns is a timely publication with broad appeal. Each chapter provides empirical evidence or models for improving stakeholders¿ understanding of campaign-related healthy ageing programmes, how the programmes are affected by the threats, and what can be done to achieve the core goals in contexts experiencing threats. Students, lecturers, and researchers can use the book as a research guide, whereas public health professionals and organizations can use it to develop or alter policies. Researchers in a wide range of disciplines can design studies based on models and insights from the book.