Bøger udgivet af Swedish Pharmaceutical Press

Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaption and rebound, dose-response-time data analysis, inter-species scaling and a lot more. A substantial effort has been invested into the new pharmacokineticsand pharmacodynamics, including many new and updated Case Studies.

This text presents a picture of biological hydroxylations and explains the functions of transition metals, Fe, Co, Mn in enzyme reactions. There are sections on shikimates, polyketides, terpenoids and alkaloids, with a further section devoted to prebiotic chemistry.