Biopharmaceutics and Pharmacokinetics - V Venkateswarlu - Bog

This book deals with the basics of the two disciplines of biopharmaceutics and pharmacokinetics. Different factors such as biological, physiochemical and formulation that influence the therapeutic efficacy of a drug are covered in biopharmaceutics. The absorption, distribution, metabolism and excretion of drugs are studied under this subject. Salient Features • Basics of biopharmaceutics and pharmacokinetics help to understand the various procedures and advances in drug design, product development, therapeutic drug monitoring, etc. • Pharmacokinetics covers the fundamentals of one compartment open model, multi-compartmental models. One compartment open model is presented in an elaborate manner to make the students familiar with various aspects of pharmacokinetics • Mathematical equations are developed using simple integration and differentiation methods • Practice problems are provided wherever necessary, and a question bank is included at the end of each chapter • Extreme care has been exercised to present the concepts in a simple way Second Edition includes • Application of principles in formulation development in industry for successful bioequivalence studies is included • One chapter on "In-vitro Dissolution Testing" is included to evaluate test formulations to chose right product for bioequivalence studies • A chapter on biostatistics with practice problems is included