Bøger i Clinical and Experimental Biomedicine serien

This book integrates topics in basic research and clinical medicine as well as molecular and cell biology. It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric oxygen treatment for COVID-19.

The book's goal is to promote the restoration and maintenance of good health, disease prophylaxis, and improved patient management by integrating research into clinical work and findings on improving care.

This book shares the experimental findings and views in current multidisciplinary medical science combining both basic and applied research aimed at resolving problematic health issues.

This book aims to disseminate and review the latest interdisciplinary medical knowledge to provide information on best clinical practice for difficult-to-treat conditions. The chapters address various aspects and approaches to the management of medical conditions that are not fully understood.

This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice.

This book focuses on recent advances regarding clinical conditions and ailments whose mechanisms remain unclear, limiting our ability to treat them.The respective chapters address a range of multidisciplinary topics related to timely or emergent research areas, such as osteoporosis in postmenopausal women, the optimal surgical procedures for vertebral compression fractures, novel rehabilitative approaches in pelvic muscle training in case of urinary incontinence, and a rational approach to balneotherapy not only for the skin but also other organ systems disorders. Alterations in the endocrine function during strenuous physical activity at high altitude ¿ a multi-stressor environment comprising hypobaric hypoxia, exercise, and nutritional changes ¿ are presented as well. Other articles provide evidence-based insights into the diagnosis, mechanisms, and clinical course of respiratory infections in children such as bronchiolitis, pneumonia, and influenza. Finally, the pros andcons of e-health are discussed; a rapidly growing area based on the use of information and communication technology to streamline the flow of health information and patient-healthcare provider connections.The content is a well-structured blend of research and practical aspects, as well as updates on cutting-edge developments. All these essential topics are presented in a format suitable for medical professionals engaged in day-to-day patient care and therapy, as well as researchers, academics, and physiotherapists.

This book gathers multidisciplinary articles that present advances of our understanding of diseases and the effective treatment of patients. The authors share recent clinical and experimental research findings, highlighting poorly understood areas with uncertain treatment outcomes, such as giant-cell bone tumors and their propensity to metastasize to the lungs; subterranean rehabilitation in pulmonary disorders; male reproductive hormone regulation during physical exercise in hyperbaric, hyperoxic environments, like underwater diving; and amelioration of cognitive decline owing to increased cerebral blood transit time after internal carotid artery stenting. Other topics include new concepts and innovations in the treatment of diabetes in pregnancy, and leg ulcers in chronic venous insufficiency, as well as molecular research on the toxic effects of oxidative stress, impaired cell autophagy, and experimental conditions resembling air pollution.Featuring the latest interdisciplinary advances in biomedicine, this book is a valuable resource for medical professionals, both academics and practitioners, and all allied health-care workers.

It also discusses metastatic renal cell carcinoma - a global scourge with an extremely poor long-term survival prognosis, the course and sequelae of renal cell carcinoma, as well as advances in targeted molecular therapy with sunitinib, a receptor tyrosine kinase inhibitor.

This book focuses on issues in clinical practice and research that are of general interest. Further, the book enhances the current body of knowledge on diagnostics and patient treatment and offers valuable new perspectives on practical clinical issues.

The book's goal is to promote the restoration and maintenance of good health, disease prophylaxis, and improved patient management by integrating research into clinical work and findings on improving care.

This book shares the experimental findings and views in current multidisciplinary medical science combining both basic and applied research aimed at resolving problematic health issues.

The latter involves mostly T cells, exemplified by cytotoxic or killer cell destroying the pathogens, or helper cells stimulating B cells to produce antibodies to bind and neutralize the pathogens.

This book addresses hot issues in the research and management of difficult-to-treat medical disorders that are commonly encountered, but for which the underlying mechanisms are often unknown.These include the adverse effects of hemodialysis and its biocompatibility in chronic kidney insufficiency, particularly related to malnutrition and inflammation, or the vulnerability of cancer patients to bacterial meningitis, the infection that remains underdiagnosed due to limited expression of symptoms. The book also covers other key topics, such as the psychological care of lung cancer patients; difficulties in the diagnosis of diffuse axonal injury in traumatic brain injury ΓÇô a disorder with a poor prognosis and high mortality rate; and the virological aspects of seasonal influenza epidemic outbreaks ΓÇô a perennial modern scourge. Further, it addresses recent developments in targeted drug delivery from titanium implants and a novel integrated thermal approach to rehabilitation of neurodegeneration-related disabilities. Featuring the latest interdisciplinary trends in biomedicine, this book connects research, theory and practice to help alleviate suffering caused by a variety of diseases.It is a resource for medical professionals, including academics, practitioners and all allied healthcare workers.

This book focuses on recent advances regarding clinical conditions and ailments whose mechanisms remain unclear, limiting our ability to treat them.The respective chapters address a range of multidisciplinary topics related to timely or emergent research areas, such as osteoporosis in postmenopausal women, the optimal surgical procedures for vertebral compression fractures, novel rehabilitative approaches in pelvic muscle training in case of urinary incontinence, and a rational approach to balneotherapy not only for the skin but also other organ systems disorders. Alterations in the endocrine function during strenuous physical activity at high altitude ¿ a multi-stressor environment comprising hypobaric hypoxia, exercise, and nutritional changes ¿ are presented as well. Other articles provide evidence-based insights into the diagnosis, mechanisms, and clinical course of respiratory infections in children such as bronchiolitis, pneumonia, and influenza. Finally, the pros and cons of e-health are discussed; a rapidly growing area based on the use of information and communication technology to streamline the flow of health information and patient-healthcare provider connections.The content is a well-structured blend of research and practical aspects, as well as updates on cutting-edge developments. All these essential topics are presented in a format suitable for medical professionals engaged in day-to-day patient care and therapy, as well as researchers, academics, and physiotherapists.

The focus of this book lies on novel aspects of rehabilitation medicine used as a treatment tool in both physical and mental spheres.The articles cover a diverse spectrum, such as rehabilitation in orthopedic pathologies, the exemplary of which is knee joint degeneration, in perioperative metastatic cancer diseases, or in neural degeneration requiring a transplant of donor nerve fibers into the defunct nerve. Advanced research studies involving proprioceptive neuromuscular facilitation, photobiomodulation, or yoga meditative techniques to regain functional ability are dealt with. The topic is expanded by a comprehensive picture of chosen molecular, genetically underpinned, diagnostics in hepatitis C infections and of novel ideas in drug design holding a curative promise in central neurodegeneration, such as development of brain-blood-barrier permeable oleic derivatives of the hydrophilic dopamine compound. The emerging rehabilitative modes and applications are posed to influence future health care delivery.The state-of-the art research is addressed to scientists, clinicians, therapists, and allied health care professionals.

This book gathers multidisciplinary articles that present advances of our understanding of diseases and the effective treatment of patients. The authors share recent clinical and experimental research findings, highlighting poorly understood areas with uncertain treatment outcomes, such as giant-cell bone tumors and their propensity to metastasize to the lungs; subterranean rehabilitation in pulmonary disorders; male reproductive hormone regulation during physical exercise in hyperbaric, hyperoxic environments, like underwater diving; and amelioration of cognitive decline owing to increased cerebral blood transit time after internal carotid artery stenting. Other topics include new concepts and innovations in the treatment of diabetes in pregnancy, and leg ulcers in chronic venous insufficiency, as well as molecular research on the toxic effects of oxidative stress, impaired cell autophagy, and experimental conditions resembling air pollution.Featuring the latest interdisciplinary advances in biomedicine, this book is a valuable resource for medical professionals, both academics and practitioners, and all allied health-care workers.

It also discusses metastatic renal cell carcinoma - a global scourge with an extremely poor long-term survival prognosis, the course and sequelae of renal cell carcinoma, as well as advances in targeted molecular therapy with sunitinib, a receptor tyrosine kinase inhibitor.

This book focuses on issues in clinical practice and research that are of general interest. Further, the book enhances the current body of knowledge on diagnostics and patient treatment and offers valuable new perspectives on practical clinical issues.

The expert contributions take on the challenges presented to medical professionals by ever growing medical knowledge and various individual and contextual issues that require a multidisciplinary approach in patient management.

The latter involves mostly T cells, exemplified by cytotoxic or killer cell destroying the pathogens, or helper cells stimulating B cells to produce antibodies to bind and neutralize the pathogens.

The focus of this book lies on novel aspects of rehabilitation medicine used as a treatment tool in both physical and mental spheres.The articles cover a diverse spectrum, such as rehabilitation in orthopedic pathologies, the exemplary of which is knee joint degeneration, in perioperative metastatic cancer diseases, or in neural degeneration requiring a transplant of donor nerve fibers into the defunct nerve. Advanced research studies involving proprioceptive neuromuscular facilitation, photobiomodulation, or yoga meditative techniques to regain functional ability are dealt with. The topic is expanded by a comprehensive picture of chosen molecular, genetically underpinned, diagnostics in hepatitis C infections and of novel ideas in drug design holding a curative promise in central neurodegeneration, such as development of brain-blood-barrier permeable oleic derivatives of the hydrophilic dopamine compound. The emerging rehabilitative modes and applications are posed to influence future health care delivery.The state-of-the art research is addressed to scientists, clinicians, therapists, and allied health care professionals.