Bøger i Current Topics in Pathology serien i rækkefølge

With contributions by numerous experts

An up-to-date review of the morphology and pathological aspects of cell receptors, important because new therapies for various pathological conditions (genetic diseases, endocrine disorders, cancer, etc.) could be based on receptor interference.

With contributions by numerous experts

In recent years, a series of excellent textbooks have been published dealing with pathology of the thyroid gland. The contributions deal with surgical pathology of the thyroid as well as with basic aspects of thyroid metabolism, hormone transport, and growth factors in thyroid cells.

During the past ten years numerous new findings have been documented in the field of gynecological pathology, especially in respect of neoplasms. The International Society of Gynecological Pathologists (ISGYP) has contributed greatly to the progress within gynecological pathology.

Despite our original intention to publish all the contributions in one book, it became necessary to divide them: Part 1 focuses on the involved nodal compartments, cell types, and functions, while Part 2 describes their reactions in inflammatory, neo plastic, and immune-deficient diseases.

The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma.

There have been many advances in the field of gastrointestinal pa thology which are of considerable clinical significance during the 13 years since the last publication of a volume of Current Topics in Pathology devoted to this subject.

Topics covered include nuclear morphology in tumour diagnosis, the ultrastructure of the nucleus, karyotypic analyses of solid tumours, flow cytometric assessment of nuclear ploidy and other parameters, histomorphometry of the nucleus, and in situ hybridisation.

The European Study Group for Cell Proliferation held its XVth Meet ing at Sundvolden, Norway, in September 1987. Inflammation is a very broad area, and the cell kinetics of the inflammatory reaction comprises a large number of topics.

This volume presents many of the pathological advances that have followed this clini cal interest, beginning with reviews of changes in biological materials obtained by in vasive investigation of joints, continuing with an account of therapy Goint replace ment) and also describing a "new" hazard - hyperbaric injury. . . . . . . . . . . . .

At this point, pathologists and researchers with a special interest in the thymus were asked to give overviews of their respective fields of interest in light of recent findings in immunology and basic insights into the structural-functional interrelationship of the human thymus.

Oral Pathology as part of the Head and Neck Pathology is an interdisciplinary field of science. The importance of these new markers shall be discussed concerning the different types of oral cancers and salivary gland tumours.

Soft tissue tumors are a very heterogeneous group of tumors in terms of histogenesis, morphology, cytogenetics, molecular biology, clinical manifestation, and prognosis.

Increasingly, pathologists are being confronted with the effects of a number of complex devices on the body. New joint systems, contraceptive devices used as drug delivery systems, and the use of new cement materials all provide challenges in terms of their pathology.

During the past few years, a considerable number of monographs on bone tumors have been published. They are mainly restricted to bone tumors as clinical-pathological entities, since their diagnosis, more than that of other tumors, requires the interdisciplinary cooperation between orthopedic specialist, radiologist, and pathologist.

With contributions by numerous experts

Professor Weller provides a detailed account of how the central nervous system may be examined in a way which permits all of us to prepare material which will allow adequate investigation of central nervous system disease and the proper examination of peripheral nerves.

With contributions by numerous experts

Concepts on the Causal Genesis of Human Intestinal Tumors The action of chemical substances has a significant role in the genesis of human tumors. It is assumed that most human tumors are induced by exogenous chemical noxae (Schmahl, 1970;Heidelberger, 1975;

Second, whether or not such antigens are truly oncofetal depends upon the method of detection used, and it has been found that here too specificity decreases as the antigen assay increases in sen sitivity.