Bøger i Updates in Surgery serien

This open access book describes the latest advances in the anal incontinence diagnostic and therapeutic processes. Anal incontinence is a devastating condition heavily impacting on the patients¿ lives. Those suffering from this disorder are generally very embarrassed and reluctant to undergo an appropriate clinical evaluation, thus becoming more isolated and worsening the quality of their life. Luckily, nowadays a wide range of treatments is available to improve this oppressive condition; however, the recognition of the related pathophysiological alterations is mandatory to grant its successful management. This volume will help the surgeons community to keep abreast of developments in diagnostics and treatment of this impairing condition. and will provide all health professionals with the appropriate tools to face this impairing condition.

This open access book offers a comprehensive review of hepatocellular carcinoma (HCC) with a particular focus on the pathobiology and clinical aspects of the disease, including diagnosis and treatment. HCC is becoming one of the most common causes of cancer-related death worldwide. It is the fifth most common malignancy in men and the ninth in women, with an estimated 500,000 to 1 million new cases annually around the world. Independent of its cause, cirrhosis is considered a major clinical and histopathological risk factor for HCC development. Five percent of all cirrhotic patients develop HCC every year. Diagnostic tools for HCC include blood tests, high-quality imaging studies and liver biopsy. The treatment of HCC depends on the size and location of the HCC and includes surgical resection, liver transplantation, endovascular approaches, percutaneous ablation, and medical treatments. The book is organized into four parts ¿ overview, diagnosis, management strategies, and recommendations ¿ and aims to provide surgeons and clinicians with a valuable resource for complete and up-to-date research on the clinical aspects and management of HCC.

The 20th century has finished, the century when surgery took huge steps forward thanks to progress in technology. Now we have entered the "century of biotechnologies", which will not only generate progress in surgery, but also lead to a real "cultural revolution" that will completely change approaches to solving different problems in medicine. The aim of this book is to bring surgeons closer to biotechnologies and to overcome the cultural gap dividing them from these new approaches. Biotechnologies are already proposed and used at different levels in surgical practice: in diagnostic technique, enabling practitioners to identify diseases at an early stage and follow their molecular modification over time; and in tissue engineering, where the use of "smart scaffolds" offers a possible answer to increasing demand for biocompatible tissues and organs in transplantation surgery. This volume focuses on the emerging field of stem cells, analyzing both their role as possible players in originating and perpetuating cancer ¿ "cancer stem cells" ¿ and, conversely, their extraordinary therapeutical potential. An additional section is dedicated to the evaluation and application of derived molecular factors that can enhance the physiological processes that are fundamentally important in surgery, such as hemostasis and wound healing. Surgeons have always been technologists, in the sense that since surgery began they have always needed technology, beginning with a scalpel and surgical instruments. They have always cooperated with technologists. However, in the new century, the first one of the millennium, a rapid increase in knowledge that is outside the realm of the surgeon¿s traditional technological training is imposing itself ¿ hence the aim of this book. It is now urgent to encourage surgeons to embrace this knowledge (biotechnology) with confidence. By its very nature, biotechnology is completely different from the technologies used so far, because it escapesthe senses of sight and touch, which up to now have been the essence of the surgeon¿s work. The cellular and molecular dimensions of biotechnologies are still far removed from most of the recent advances in modern surgical techniques. A common language between surgeons and biotechnologists will create further, revolutionary, progress in surgical sciences in the twenty-first century.

This is the first time a book about laparoscopy in emergency abdominal surgery has been published. Numerous articles have been published in specific surgical journals, but, until now, there has not been a book that collates all the aspects of this little-known field. The aim of this volume is to achieve a complete and easy presentation of all the implications associated with laparoscopy in emergency abdominal surgery. The book should be a manual that can be easily consulted by digestive, general, and specialized surgeons, especially in an emergency. The authors¿ contributions are founded on evidence-based medicine, which give the book scientific credibility, but this is coupled with their experience of daily practice, which adds an important complementary dimension to evidence-based medicine. This is balanced by an emphasis on clarity and accessibility, because the ultimate aim of the book is educational. We hope this book will be frequently consulted, in depth, not only by specialistpractitioners, but also by undergraduate students, new graduates and surgeons in training.

The 20th century has finished, the century when surgery took huge steps forward thanks to progress in technology. Now we have entered the "century of biotechnologies", which will not only generate progress in surgery, but also lead to a real "cultural revolution" that will completely change approaches to solving different problems in medicine.The aim of this book is to bring surgeons closer to biotechnologies and to overcome the cultural gap dividing them from these new approaches. Biotechnologies are already proposed and used at different levels in surgical practice: in diagnostic technique, enabling practitioners to identify diseases at an early stage and follow their molecular modification over time; and in tissue engineering, where the use of "smart scaffolds" offers a possible answer to increasing demand for biocompatible tissues and organs in transplantation surgery.This volume focuses on the emerging field of stem cells, analyzing both their role as possible players in originating and perpetuating cancer - "cancer stem cells" - and, conversely, their extraordinary therapeutical potential. An additional section is dedicated to the evaluation and application of derived molecular factors that can enhance the physiological processes that are fundamentally important in surgery, such as hemostasis and wound healing.Surgeons have always been technologists, in the sense that since surgery began they have always needed technology, beginning with a scalpel and surgical instruments. They have always cooperated with technologists. However, in the new century, the first one of the millennium, a rapid increase in knowledge that is outside the realm of the surgeon's traditional technological training is imposing itself - hence the aim of this book.It is now urgent to encourage surgeons to embrace this knowledge (biotechnology) with confidence. By its very nature, biotechnology is completely different from the technologies used sofar, because it escapes the senses of sight and touch, which up to now have been the essence of the surgeon's work.The cellular and molecular dimensions of biotechnologies are still far removed from most of the recent advances in modern surgical techniques. A common language between surgeons and biotechnologists will create further, revolutionary, progress in surgical sciences in the twenty-first century.

Incisional hernia surgery has witnessed an important progress over the last years, not only as far as the pathophysiological and etiopathogenetic aspects are concerned, but also from a technical point of view. Thanks to the recent findings on genetical disorders of the collagen, incisional hernia is today considered a true "disease of the abdominal wall". Surgeons need to be aware of all the different repairing techniques, in order to make an elective choice and to keep side effects and recidives under control. Today, on the basis of the most recent research on synthesis of collagen and collagenolysis, the treatment of the incisional hernia should not disregard the use of synthetic prostheses and of biomaterials, both in the routinal surgical practice and in the most complex clinical cases. Surgeons, surgical residents, and medical students will find this volume very useful in their daily practice.

Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy.

This book offers an overview of acute care surgery around the world, focusing on the four main branches of this novel subdiscipline: trauma, general emergencies, critical care, and rescue surgery.

In the last decade, the clinical management of melanoma has become more effective: basic clinical studies, randomized clinical trials, and new drugs have greatly improved the prognosis of patients, both in the initial and in the advanced stage of the disease.This book offers a wide and up-to-date overview of the multidisciplinary treatment of melanoma. Among the topics discussed, there are the role of sentinel lymph node biopsy and the radical dissection, following the results of international randomized clinical trials, in particular MSLT-II. The last chapters are focused on new medical treatments in adjuvant, neoadjuvant, and metastatic settings. The volume has been written for all the professionals involved in melanoma treatment, such as general surgeons, surgical oncologists, medical oncologists, dermatologists, radiotherapists, and nuclear medicine physicians.

The book offers a comprehensive review of the relations between volumes and outcomes in oncological surgery especially in Italian hospitals, based on national and regional data.

Once a clinical curiosity, multiple malignant tumors (MMT) are becoming more common. This state-of-the-art overview of MMT offers a clear definition and classification and explores various aspects including genetic, iatrogenic and environmental factors.

Up-to-date and comprehensive, this surgical manual provides clear descriptions of current procedures as well as guidance on managing difficult cases. It enables an informed and multidisciplinary approach to a cancer that is increasing in frequency.

Cross-imaging enables detection of small pancreatic lesions that now prompt the majority of surgical procedures in asymptomatic patients. This volume is an expert guide to the latest evidence and knowledge of these uncommon tumors of the pancreas.

Here is a comprehensive review of the newest techniques in minimally invasive liver surgery. Describes tools and technology and illustrates details of operative techniques. Includes illustrations and photos, and a DVD containing videos of technical procedures.

This book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments.

This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally.

This is the first time a book about laparoscopy in emergency abdominal surgery has been published. The authors' contributions are founded on evidence-based medicine, which give the book scientific credibility, but this is coupled with their experience of daily practice, which adds an important complementary dimension to evidence-based medicine.

This comprehensive, multi-authored book covers all aspects of surgery on obese patients in emergency conditions. Obesity is a metabolic disease affecting a high percentage of world population..

This book provides a unique and comprehensive overview of minimally invasive (MI) surgical options for the treatment of pancreatic diseases.

This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks.

This practice-oriented book provides a comprehensive and up-to-date review of the history, surgical anatomy, etiology, pathogenesis, clinical presentation and treatment of primary, secondary, and tertiary hyperparathyroidism.

This book, which describes in detail the most common procedures employed in inguinal hernia surgery, is exceptional in reflecting fully the most recent advances, as well as the most established techniques, in knowledge and practice.

This book reviews the latest advances in treating ulcerative colitis. Its structure is designed to reflect the natural presentation of the disease; accordingly, it starts with the symptoms and the clinical picture, before addressing the use of radiological and endoscopic studies that are performed to make a diagnosis, and the role of the pathological examination. The book also includes detailed information on the medical treatment of the disease, written by some of the most expert gastroenterologists in the field, while also paying considerable attention to the latest medical treatments and to expected future developments.The book describes various surgical techniques for ulcerative colitis in detail, providing readers with concrete guidelines on which is the most appropriate operation to perform in any given case. It also presents extensive information on the most important operation, the formation of the IPAA (ileal pouch-anal anastomosis), together with helpful tips and tricks. A closing chapter addresses the long-term complications that can occur after a pouch formation, and what to do for each case. As such, the book offers a unique and comprehensive guide for surgeons, gastroenterologists, researchers and students alike.

This book provides a comprehensive overview of the approach to retroperitoneal sarcomas, rare and challenging tumors requiring highly specialized, multidisciplinary management.

This book provides a unique and comprehensive overview of minimally invasive (MI) surgical options for the treatment of pancreatic diseases.

This book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments.

This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks.

During recent decades, more than 100 surgical procedures have been proposed to treat pelvic organ prolapse, and surgeons are still searching for the ideal approach.