Metabolisme

The gland in the body which produces the hormones that regulate the utilization of energy by the body is known as the thyroid gland. The disorders related to this gland may lead to the production of too less of this hormone or too much, which can result in hypothyroidism or hyperthyroidism respectively. This in turn can cause symptoms such as weight loss, weight gain, irritability and fatigue. Some of the other disorders of the thyroid gland are goiter, thyroid cancer and thyroiditis. Different approaches, evaluations and case studies on thyroid disorders have been included in this book. Those in search of information to further their knowledge will be greatly assisted by it.

Endocrinology is an area of medical science that focuses on the study and treatment of disorders related to the endocrine system. The endocrine system consists of glands that produce hormones, which are essential for regulating various bodily functions. There can be several causes of endocrine disorders. They can arise from hormone-producing glands, such as the thyroid, adrenal glands, pituitary gland, pancreas, or the ovaries and testes. The symptoms of endocrine disorders vary depending on the specific gland and hormones involved. A few of the common symptoms include fatigue, weight changes, mood swings, abnormal growth patterns, changes in sexual function, excessive thirst or urination, and changes in appetite. Diagnosing endocrine disorders involves a thorough review of medical history, physical examination, and laboratory tests. Imaging techniques such as ultrasounds, CT scans, or MRIs may also be used to visualize the affected glands or detect tumors. This book is a compilation of case studies that discuss the most vital concepts and emerging trends in the field of endocrinology. Those in search of information to further their knowledge will be greatly assisted by it.

The endocrine system consists of various glands in the body that produce hormones, including the thyroid, adrenal glands, pancreas, and pituitary gland. The field of oncology that focuses on the diagnosis, treatment, and management of cancers related to the endocrine system is known as endocrine oncology. Cancers that develop in these glands or involve the production of hormones are referred to as endocrine tumors or endocrine neoplasms. Some of the major types of endocrine tumors are thyroid cancer, adrenal cancer and pituitary tumors. Thyroid cancer originates in the cells of the thyroid gland and can include types such as papillary, follicular, medullary, and anaplastic thyroid cancer. Adrenal cancer develops in the adrenal glands, which produce hormones such as cortisol and adrenaline. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of endocrine oncology. It will serve as a reference to a broad spectrum of readers.

Endocrinology is a specialized field of medicine that focuses on the endocrine system, which includes glands that produce hormones to regulate various bodily functions. This field encompasses a wide range of disorders related to hormone imbalances and dysfunctions. These include thyroid disorders, polycystic ovary syndrome, and adrenal gland disorders. Thyroid disorders can involve either an overactive or underactive thyroid gland. Treatment options for these type of disorders may include medication to restore hormone balance, radioactive iodine therapy, or in some cases, surgical removal of the thyroid gland. Polycystic ovary syndrome is a hormonal disorder that affects women and can cause irregular menstrual periods, excess hair growth and fertility problems. The book aims to shed light on some of the unexplored aspects of endocrinology and the recent researches in this field. It will serve as a valuable source of reference for graduate and postgraduate students.

This thorough volume explores protocols of proteome- and metabolome-wide strategies for the identification of protein-small molecule complexes in different organisms, in order to shed light on these important regulatory interactions. Experimental and computational strategies to characterize protein-metabolite interactions are discussed, and recent advances in enabling technologies are featured as well. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice to ensure success in future research. Authoritative and practical, Cell-Wide Identification of Metabolite-Protein Interactions will aid researchers seeking a better understanding of the mechanisms of signal transduction occurring in the cell and assessing the effect of complex formation on cell physiology.

If you have hyperthyroidism, including Graves' disease or toxic multinodular goiter, and are looking for a natural treatment solution to get to the underlying cause of your condition, then this book will show you how to restore your health naturally...and avoid radioactive iodine and thyroid surgery.

Embark on a powerful and inspirational journey with Dawn Green as she battles against the odds in a 35-year-long quest to uncover the truth behind her mysterious and life-threatening health issues. This gripping memoir takes readers through the highs and lows of an extraordinary life marked by persistence, resilience, and unwavering hope.The book opens with the author's early years, when she first realized that her health was beginning to decline. In succession, a series of perplexing symptoms began to plague her. Initially her concerns were dismissed by her mother. Unfortunately, these symptoms intensify over time, transforming her sickly body into one of fatigue, pain, and desperation.With each passing year, the author navigates a labyrinth of misdiagnoses and medical uncertainty, facing a medical system that often overlooks that main test needed to determine the root cause. As her health deteriorates, her spirits remain unyielding, and she embarks on a determined mission to find answers.Through talking with her doctors and relentless self-advocacy, Dawn finally gets the test she needs and discovers the elusive diagnosis - multiple autoimmune diseases. These invisible illnesses are so aptly named, as they often cause immense suffering while oftentimes leaving no visible signs of distress on the outside.With the truth revealed, Dawn's transformative journey begins. She courageously embarks on a holistic healing path, recognizing that her frail body needs more than conventional medical treatments alone. Moreover, this book highlights the exploration of alternative modalities and therapies that play a crucial role in Dawn's recovery journey. Embracing practices like fasting, infrared saunas, meditation, and herbal remedies, she finds solace and strength, both physically and emotionally. While the book is filled with anecdotes of the author's relentless spirit, it also touches on the inevitable moments of doubt and despair. The emotional toll of living with invisible illnesses is candidly explored, allowing readers to empathize with the complexities of the author's journey.Facing My Giants isn't just a personal account of the author's struggle but a call to action for the world to recognize the plight of those living with invisible illnesses. By shedding light on the challenges faced by those who may appear healthy on the surface but battle severe illnesses within, the book seeks to raise awareness and foster compassion.In this remarkable memoir, readers will find a message of hope and resilience. Facing My Giants is a triumphant story of one woman's courage to confront life's darkest moments and emerge stronger, wiser, and determined to thrive despite the odds. Come along to explore the tools necessary to be your own health advocate and to work in conjunction with your doctor to achieve the lifelong health benefits you desire and deserve through a self-prescribed plan tailored to your unique needs. In Facing My Giants, Dawn Green illuminates your path to inspire you to discover and embrace the understated potential of self-care. No matter where you are in your health journey, imagine implementing proven protocols that will transform your mind and body, instilling a renewed sense of confidence and enabling you to take back your health and live in ways that were inconceivable. With each new breath, you will inhale confidence and exhale hope.

Endocrinology is an area of medicine that focuses on the study of hormones and the endocrine system. Hormones are chemical messengers which are produced by the different glands in the body that regulate numerous physiological processes, such as growth, metabolism, reproduction and mood. The endocrine system comprises glands such as the pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries (in females), and testes (in males). Endocrinology is involved in the diagnosis of patients with hormonal disorders through a combination of clinical assessment, laboratory tests and imaging studies. It also deals with the management of medical conditions which include diabetes mellitus, thyroid disorders, adrenal disorders, disorders of the reproductive system, and pituitary disorders. This book unfolds the innovative aspects of endocrinology which will be crucial for the progress of this field in the future. It will serve as a valuable source of reference for graduate and postgraduate students.

Type 1 diabetes is an autoimmune disease in which the body's immune system attacks and destroys cells in the pancreas, which are responsible for producing insulin in the body. It causes an absolute destruction of insulin-producing beta cells that leads to insulin deficiency. Some symptoms of type 1 diabetes are extreme hunger, increased thirst, frequent urination, tiredness, etc. Urine test can be done to find out the presence of a byproduct, where fat tissue and muscle are used for generating energy, as body does not have sufficient insulin for utilizing glucose. Tests can also be run to check for autoantibodies related with type 1 diabetes. The main treatment for this disease involves the administration of insulin through daily injections or an insulin pump. Some other treatments for type 1 diabetes are frequent monitoring of blood sugar levels and carbohydrate counting. This book outlines the etiology and treatment of type 1 diabetes in detail. It consists of contributions made by international experts. This book is a complete source of knowledge on the present status of this important disease.

Thyroid diseases are those that affect the function of the thyroid gland. This gland is butterfly-shaped and is located towards the front of the neck. It produces hormones that flow into the bloodstream and play an essential role in regulating metabolism, heart rate, body temperature, food movement through the digestive tract, brain development, etc. Thyroid disorders are divided into many categories, such as, hypothyroidism, hyperthyroidism, structural abnormalities such as goiter and tumors. Tiredness, muscle cramps, constipation, weight loss, and slow heart rate are a few symptoms of hypothyroidism whereas hyperthyroidism is symptomatized by insomnia, fast heart rate, weight gain, anxiety, tremors, excess sweating, etc. This book unfolds the most recent researches related to thyroid diseases. From theories to research to practical applications, case studies related to all contemporary topics of relevance to these disorders have been included herein. This book will serve as a useful resource for experts as well as students.

The thyroid is a butterfly-shaped gland that is located in the front of the neck. Thyroid cancer is a condition in which the cells grow abnormally and can spread to other parts of the body. Swelling or a bump in the thyroid part of the neck is a common symptom of this medical condition. Thyroid cancers are known to be linked to a variety of genetic and environmental variables. Radiation exposure as a child, an enlarged thyroid, and a family history are all risk factors for thyroid cancer. Papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and anaplastic thyroid cancer are the four primary types of thyroid cancer. Ultrasound and fine needle aspiration are used to diagnose this disease. Surgery, thyroid hormone therapy, radiation therapy, chemotherapy, alcohol ablation, targeted therapy, and palliative care are all possible treatment options. The topics covered in this book offer the readers new insights in the field of thyroid cancer research. It includes some of the vital pieces of work being conducted across the world, on various topics related to this disease. For all readers who are interested in the research on thyroid cancer, the case studies included in this book will serve as an excellent guide to develop a comprehensive understanding.

Sirtuins refer to a class of signaling proteins involved in metabolic regulation. They are members of the class III family of NAD-dependent histone deacetylases (HDAC). They are involved in a variety of physiological processes ranging from metabolism and endocrine function control to immune coordination and cellular responses to stress. Sirtuin-1 (SIRT1) plays an important role in epigenetics, immunology, and endocrinology. SIRT1's diverse roles include energy sensing metabolic homeostasis regulation, and deacetylation of histone and non-histone proteins in numerous tissues. It also facilitates neuro-endocrine regulation through hypothalamus-pituitary axis stimulation, and synthesis and maintenance of reproductive hormones via steroidogenesis. Some of the other functions involve maintenance of innate and adaptive immune systems via T and B cell maturation regulation, chronic inflammation, and autoimmune diseases. This book provides significant information of sirtuin biology as well as its importance in endocrinology and metabolic disease. It will provide comprehensive knowledge to the readers.

Pharmacokinetics (PK) determines the outcome of substances which are administered in the human body and involves drug absorption, distribution, metabolism, and excretion (ADME) processes. Drug absorption is the movement of drug in the bloodstream from its site of administration. It depends on multiple factors, including the formulation and chemical properties of a drug, drug-food interactions and route of administration. Drug distribution is essential for determining drug efficacy and drug toxicity. Drug metabolism is the chemical alteration of the drug by the body. Genetics, age and drug interactions are some factors that affect drug metabolism. In clinical use, an enzyme named cytochrome P450 (CYP450) is responsible for the biotransformation or metabolism of all drugs. It is essential to comprehend the basic mechanisms governing the pharmacokinetics of a drug for designing personalized course of therapy for patients. This book provides comprehensive insights into the role of pharmacokinetics and metabolism in drug design. It is appropriate for students seeking detailed information in this area of study as well as for experts.

Metabolic syndrome is referred to as the presence of at least three of the five medical conditions, including high blood sugar, abdominal obesity, low serum high-density lipoprotein (HDL), high blood pressure and high serum triglycerides. Ethnicity, a high-fat diet, aging, a history of frequent drinking and stress are some of the risk factors strongly linked to metabolic syndrome. The risk of acquiring type 2 diabetes and cardiovascular disease is correlated with metabolic syndrome. Its diagnosis involves measuring blood pressure, fat levels, waist circumference and fasting blood sugar. There are several ways of preventing and managing metabolic syndrome such as quitting smoking and other tobacco products, eating a balanced diet, being physically active, and maintaining a healthy weight. This book presents the complex condition of metabolic syndrome in the most comprehensible and easy-to-understand language. From theories to research to practical applications, case studies related to all contemporary topics of relevance to metabolic syndrome have been included in this book. Its extensive content provides the readers with a thorough understanding of this medical condition.