Onkologi

An insider view of the surprising innovations, collaborations and human stories behind our most vital medicines.

Bogen her handler om brystkræft og operation. Den er en del af en lille serie af børnebøger, der omhandler de trebehandlingstiltag, som brystkræftpatienter typisk gennemgår: operation, kemoterapi (enten før eller efter operation) og strålebehandling. Alle brystkræftforløb er forskellige, men temaerne er universelle. Hvordan forklarer man et barn, hvad en kræftcelle er, og hvad behandlingen gør? Hvordan får man talt om frygt, ondt i maven, hårtab, ar, træthed og meget andet?Bogen er en invitation til samtale om det, barnet kan genkende sig selv i – rammet ind af et magisk illustrativt univers i børnehøjde. Den henvender sig til børn i alderen 6-12 år og er tænkt til højtlæsning. Børn har brug for samtalerom det, der er svært og nyt. Ellers efterlades de alene medderes forestillinger. Denne lille serie af små bøger behandlerstore spørgsmål og lige så store følelser.

Bogen her handler om brystkræft og operation. Den er en del af en lille serie af børnebøger, der omhandler de trebehandlingstiltag, som brystkræftpatienter typisk gennemgår: operation, kemoterapi (enten før eller efter operation) og strålebehandling. Alle brystkræftforløb er forskellige, men temaerne er universelle. Hvordan forklarer man et barn, hvad en kræftcelle er, og hvad behandlingen gør? Hvordan får man talt om frygt, ondt i maven, hårtab, ar, træthed og meget andet?Bogen er en invitation til samtale om det, barnet kan genkende sig selv i – rammet ind af et magisk illustrativt univers i børnehøjde. Den henvender sig til børn i alderen6-12 år og er tænkt til højtlæsning. Børn har brug for samtalerom det, der er svært og nyt. Ellers efterlades de alene medderes forestillinger. Denne lille serie af små bøger behandlerstore spørgsmål og lige så store følelser.

Bogen her handler om brystkræft og operation. Den er en del af en lille serie af børnebøger, der omhandler de trebehandlingstiltag, som brystkræftpatienter typisk gennemgår: operation, kemoterapi (enten før eller efter operation) og strålebehandling. Alle brystkræftforløb er forskellige, men temaerne er universelle. Hvordan forklarer man et barn, hvad en kræftcelle er, og hvad behandlingen gør? Hvordan får man talt om frygt, ondt i maven, hårtab, ar, træthed og meget andet?Bogen er en invitation til samtale om det, barnet kan genkende sig selv i – rammet ind af et magisk illustrativt univers i børnehøjde. Den henvender sig til børn i alderen 6-12 år og er tænkt til højtlæsning. Børn har brug for samtalerom det, der er svært og nyt. Ellers efterlades de alene medderes forestillinger. Denne lille serie af små bøger behandlerstore spørgsmål og lige så store følelser.

This book reviews the potential of metallodrugs against different cancer. It summarizes the classification of metal-based anti-cancer drugs, their plausible biochemical and mechanistic pathways, combining drug strategies for hitting multiple therapeutic targets at the intracellular level, and advanced drug delivery strategies. The book covers the metallodrugs for the efficacious treatment of diverse cancerous strains and recent advances in drug delivery strategies that are used for developing these metal-based therapeutics as potent anticancer agents in vitro and in vivo. The book also covers different biophysical and analytical techniques for studying metal-ligand and metal-macromolecular interactions. The book further presents the recent examples of metallomics studies on the different types of cell death induced by metal-based anticancer drugs, especially on the three major forms of programmed cell death (PCD) in mammalian cells: apoptosis, autophagy, and regulated necrosis, alsocalled necroptosis. Lastly, the book explores the modulation of reactive oxygen species (ROS) by metallodrugs.

This book focuses on recent trends of research on alginate-based biomaterials in Drug Delivery strategies and biomedical engineering. It contains the widely used alginate-based biomaterials as micro to nano-controlled drug delivery (oral, ocular delivery, topical delivery, etc.) and its fabrication technology, characterization, and biomedical aspects (such as cancer therapy, tissue engineering, gene delivery, vaccine delivery, enzyme immobilization, wound healing, dental applications, etc.) in a single book. The chapters cover updated information, current research trends, informatics, and all aspects of applications. Alginate is a U.S. Food and Drug Administration (FDA)-approved natural biomaterial and has diverse biomedical applications. In recent years, researchers and scientists are working on the alginate-based drug delivery systems that have been designed and characterized as a matrix, micro to nanocarriers, fibers, composite/scaffolds, etc. Alginate has versatile properties such as biodegradable, biocompatible, nontoxic, and easily available. This book especially highlights both the drug delivery strategies and biomedical engineering aspects such as controlled drug delivery, drug targeting to the site of action, cancer therapy, gene and vaccine delivery, enzyme immobilization, tissue engineering, and regenerative medicine.

The book discusses the recent progress in understanding the therapeutic targets for gallbladder cancer to provide opportunities for research and for developing innovative strategies that may enhance the benefit of conventional chemotherapy.The book focuses on identifying candidate molecules and the overall status of the targeted therapies available for gallbladder cancer, as there is an urgent need to discover new molecular targets that can guide the emergence of new treatment strategies to improve patient outcomes and act as biomarkers for the early detection of diseases. Recently, new treatment therapeutics targets for gallbladder cancer patients have been identified and the field is evolving rapidly.The book is relevant for the clinical researcher, surgeon, scientist and academician.

This volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed.Helicobacter pylori is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world¿s population. H. pylori and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by thisbacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer-related death worldwide. H. pylori is the first bacterium that has been classified as a type-I carcinogen by the International Agency for Research on Cancer (IARC). Recent research progress identified crucial bacterial, host and environmental factors which control H. pylori-induced gastric malignancy. New studies also suggest that specific human germline mutations and other genetic aberrations have an important impact on H. pylori-induced pathology. In this volume, all these recently discovered mechanisms are reviewed in the light of gastric cancer development, and H. pylori epidemiology, virulence factors, immune evasion, pathophysiology, cancer signalling and novel therapeutic protocols are presented. This volume is aimed at researchers in the fields of immunology, genetics, microbiology and medicine who are interested in the detailed mechanisms of the pathogenicity of this carcinogenic stomach bacterium.

For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties.

Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the ¿Interdisciplinary Cancer Research¿ series, entitled ¿Gastrointestinal Cancers: An Interdisciplinary Approach¿ publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.

Cancer treatment is a challenging issue, while the treatment modalities have extended from traditional surgery, chemotherapy, and radiation therapy to new therapeutic approaches, including targeted therapy, immunotherapy, stem cell transplantation, and hormone therapy. Therefore, an interdisciplinary approach is needed to find a better therapeutic protocols in order to increase the prognosis and quality of life of patients with cancer.The second volume of the ¿Interdisciplinary Cancer Research¿ series, entitled ¿Cancer Treatment: An Interdisciplinary Approach¿ publishes comprehensive volumes on different cancer treatment modalities and presents the most updated and peer-reviewed articles on cancer therapy. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers and clinicians who wish to extend their knowledge on cancer treatment.

In "Bone Cancer Demystified: Doctor's Secret Guide," Dr. [Your Name] provides an insightful and compassionate exploration of bone cancer, offering a wealth of knowledge for patients, caregivers, and anyone seeking to understand this complex condition. Beginning with a thorough introduction and an understanding of what bone cancer entails, the book navigates through the anatomy of bones, exploring various types of bone cancer and the crucial symptoms to watch for. Dr. [Your Name] explains the staging and grading of bone cancer and sheds light on how it spreads.Dispelling myths and presenting facts, the book introduces the Biopsychosocial Model in cancer care, emphasizing the interconnected aspects of biology, psychology, and social support. From the biology of healing to the psychological impact of bone cancer, readers gain profound insights into holistic approaches to care. The importance of social support systems is highlighted, and the book delves into integrating mind, body, and society for comprehensive well-being. Practical tools, such as stress management techniques and the power of positive thinking, are explored, supported by real-life biopsychosocial case studies.Prevention and risk reduction strategies are a central focus, covering genetic and hereditary factors, environmental contributors, and the role of nutrition and physical activity. The book emphasizes the importance of preventive health screenings, avoiding carcinogens, and the potential impact of vaccinations on bone cancer prevention.For those facing a diagnosis, Dr. [Your Name] provides a detailed guide to the medical assessment process, from the initial consultation and blood tests to imaging techniques and biopsy procedures. The book clarifies pathology reports, advocates for seeking second opinions, and guides readers through understanding their diagnosis."Bone Cancer Demystified" is not just a medical guide; it's a holistic resource that empowers individuals with knowledge, fosters resilience, and provides a roadmap to navigate the complexities of bone cancer with confidence.

The nanotheranostics sector provides a very promising strategy for monitoring drug biodistribution and pathology longitudinal processes by integrating the imaging and drug delivery functions in one single nanoformulation, providing vital insights into the identification of tumour and predicting the efficacy of nanomedicine. For its unique properties, which include their small size and biocompatibility and ability to permeate the cellular membrane with carrying drugs, nanomaterials have been used for various biomedical applications. This book covers the progress made in hormone-related cancer and their management by nonmedicinal therapy for targeting the hormone regulated cancer with their clinical progress and clinical hurdles.

In the domain of oncology, the mission for successful and creative disease treatment procedures has arrived at a significant second. "Altering Malignant growth Therapy Systems" investigates the state of the art progressions that are reshaping the scene of disease care and carrying newly discovered desire to patients around the world. The book starts by digging into the groundbreaking force of customized medication. Customary disease medicines have frequently taken a one-size-fits-all methodology, yet late leap forwards in genomics and sub-atomic science have made ready for accuracy medication. Perusers will set out on an excursion through the complexities of hereditary profiling, understanding how individualized treatments are custom-made to the extraordinary hereditary cosmetics of every patient's growth. This designated approach upgrades therapy viability as well as limits secondary effects, denoting a change in perspective in the battle against malignant growth. Immunotherapy arises as an encouraging sign in the book, displaying how the body's own resistant framework can be saddled to battle disease cells. From safe designated spot inhibitors to supportive cell treatments, the story unfurls with accounts of astounding recuperations and the commitment of solid reactions. Perusers gain knowledge into the notable Vehicle Lymphocyte treatments and the phenomenal examples of overcoming adversity of patients who have encountered noteworthy reductions, proclaiming another period in malignant growth immunotherapy. The investigation reaches out to the cutting edge of nanotechnology, where little ponders are having a major effect in disease treatment. Nanoparticles, drug conveyance frameworks, and designated treatments at the sub-atomic level are uncovered as huge advantages in the battle against malignant growth. The book explains how these infinitesimal developments are expanding drug viability while limiting fundamental poisonousness, introducing an original road for more okay and compelling malignant growth medicines. "Altering Malignant growth Treatment Methodologies" doesn't avoid the job of man-made consciousness (artificial intelligence) and AI in reshaping the scene of oncology. Perusers will observer how these advances dissect tremendous measures of clinical information, foresee treatment reactions, and aid early identification, introducing another time of information driven, patient-driven care. The story closes with a look toward the future, investigating arising treatments like CRISPR quality altering and the reconciliation of mechanical technology in medical procedure. As science and innovation keep on meeting with human versatility, the book remains as a demonstration of the noteworthy headway made in the field of malignant growth therapy, offering a brief look into a future where disease might be vanquished through resourcefulness, empathy, and constant devotion to the prosperity of those confronting this impressive enemy.

The book "Nuclear Medicine Clinical Procedures for Technologists" serves as a valuable resource not only for Kuwait University's Faculty of Allied Health nuclear medicine students but also for nuclear medicine technology students worldwide. Its purpose is to assist them in their clinical studies and offers valuable insights, general guidelines, and imaging protocols for a wide range of nuclear medicine examinations, drawing from personal experiences of a nuclear medicine technology student gained at various nuclear medicine departments. Whether you are a student, practitioner, or enthusiast of nuclear medicine, this comprehensive guideline is designed to facilitate the understanding and implementing key procedures in this dynamic and ever-evolving field.

"Beyond the Marrow: Understanding and Beating Acute Myeloid Leukemia" is a comprehensive and compassionate guide that delves into the intricate landscape of Acute Myeloid Leukemia (AML). Written with both patients and their families in mind, this book offers a thorough exploration of AML, from its underlying biology and diagnosis to the latest advancements in treatment.Readers will embark on a journey through the medical intricacies of AML, demystifying complex concepts and providing clarity on genetic mutations, risk factors, and the evolving landscape of therapeutic options. The book combines accessible explanations with the latest scientific knowledge, empowering individuals to make informed decisions about their care.Interwoven with the science is the human side of the AML experience. Personal stories of resilience and triumph over AML serve as beacons of hope, illustrating that a diagnosis is not the end but the beginning of a fight that can be won."Beyond the Marrow" extends its reach beyond medical insights, addressing the emotional and practical aspects of the AML journey. From coping strategies and psychosocial support to practical advice on navigating treatment, this book is a holistic resource for those facing AML.Informed by the latest research and international collaborations, "Beyond the Marrow" is a guide, companion, and source of inspiration for anyone touched by AML. It is a testament to the strength of the human spirit and the collective efforts to overcome the challenges posed by Acute Myeloid Leukemia.

This book addresses Epigenetics in Cancer and covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years.Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resourcefor scientists, graduate students and clinicians alike.

Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

"The Thyroid Cancer Mastery Bible: Your Blueprint for Complete Thyroid Cancer Management" is a comprehensive guide empowering readers to navigate every aspect of their thyroid cancer journey. From understanding the basics of thyroid function and recognizing early warning signs to dispelling myths and decoding pathology reports, this book provides a holistic view. The diagnostic journey is explored, emphasizing the psychological impact and the importance of second opinions. Treatment strategies, including surgery, radioactive iodine therapy, and emerging targeted therapies, are discussed alongside integrative approaches and participation in clinical trials. Delve into holistic management, incorporating nutrition, physical activity, stress reduction techniques, and emotional healing. The book addresses life after treatment, guiding readers on monitoring for recurrence, managing long-term side effects, and embracing thyroid hormone replacement therapy. Beyond medical aspects, readers gain insights into vocal rehabilitation, career and financial planning, and navigating relationships. Look into the future of thyroid cancer care with discussions on emerging treatments, genomics, immunotherapy, and the impact of artificial intelligence. This guide not only informs but empowers, fostering patient advocacy and contributing to global health initiatives. With a focus on prevention and awareness, this book is a beacon for those seeking a personalized blueprint for a life beyond thyroid cancer.