Kardiologi

Acute coronary syndrome (ACS) continues to challenge our health care system in the complexity of presentation and the ever increasing number of patients exhibiting signs and symptoms of an acute coronary syndrome. Written by leading experts, Short Stay Management of Chest Pain provides scientific and clinical insights on the management of patients who arrive at the hospital with a presentation consistent with a potential acute coronary syndrome. Focusing on the cardiology aspects of chest pain, Short Stay Management of Chest Pain is a valuable tool for acute care physicians, nurses, and hospital administrators devoted to caring for this population. Short Stay Management of Chest Pain details the remarkable improvements in diagnostic accuracy and improved patient outcomes for patients presenting with suspected acute coronary syndromes.

This book, written by internationally renowned experts, is a comprehensive text covering all aspects and recommendations regarding the use of POCUS for critically ill neonates and children. Point of Care Ultrasound (POCUS) for the Neonatal and Pediatric Intensivist is structured to address and expand upon recently published international evidence-based POCUS guidelines endorsed by the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).The book is richly illustrated and includes a robust collection of individual POCUS images and cases. The Electronic Supplementary Materials offer high quality and interesting video clips complementing reader learning, particularly for neonatology, pediatric critical care, and general pediatric providers. Chapter authors provide a practical, experience-based approach to clinical integration of POCUS applications and highlight relevant supportive literature as well as important limitations to POCUS use in the management of critically ill children. The information within the book is also intended to support further clinical and educational research in the practice of pediatric POCUS.

This second edition volume expands on the previous edition with updated techniques and discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Cardiac Gene Therapy: Methods and Protocols, Second Edition is a valuable tool for researchers in cardiology who are conducting gene therapy research. This book will lead to further advancements and successful clinical translations in the field. Chapter "e;Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcombo"e; is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This text provides comprehensive atlas of open arterial reconstructions - primary and reoperations. This book describes in detail the 1) indications of the operation, 2) surgical anatomy 3) operative steps in a sequential order with easy to understand illustrations, 4) recognizing a potential complication 5) and if a complication occurs, the steps involved in managing the complication.

The book is a compact yet comprehensive practical resource that highlights all must-know information on non-alcoholic fatty liver disease (NAFLD). Covering the major issues dominating the field, this book offers a broad vision on NAFLD using key data for a deep and thorough understanding of the latest diagnostic methods, treatment options, potential complications, and disease management strategies to improve patient outcomes. The volume bridges the trans-disciplinary divide between hepatologists, cardiologists, nephrologists, psychiatrists, oncologists and dermatologists in order to cover the complex management of NAFLD in a single volume. It operates under a modern definition of NAFLD that acknowledges the range of presentations related to extrahepatic complications that hepatologists see in daily practice, while also delving into unanswered questions and future directions regarding treatment options. Offering practical, clinical guidance in addition to capturing the new promising therapeutic approaches in the pipeline, this book is an essential reference for clinicians, researchers and students.

The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery.

This book offers a practical guidance to healthcare professionals interested in learning how to make adequate clinically-oriented use of cardiovascular MRI. Thanks to its case-based approach, it provides a detailed guide to MRI applications in the most common clinical cardiovascular scenarios. Chapters describe a number of real clinical cases, including concise clinical data, clear descriptions of the most relevant information obtained from MRI and of their meaning in terms of patient management. Emphasis is placed on traditional as well as newer MRI techniques, always keeping a practical format, focused on the hands-on knowledge required for an accurate image interpretation. In the online version, the text of each case is supplemented with additional images and videos, certainly making this book a useful resource for understanding how MRI principles apply to real clinical cardiovascular situations.

Cardiovascular disease is currently the leading cause of death of pregnant and postpartum women in the United States. Pregnancy can exacerbate known cardiovascular disorders and unmask previously unrecognized problems. The field of cardio-obstetrics is emerging and a clear area of need for improved quality of care.This book is the first authoritative and comprehensive volume dedicated to contemporary and practical topics in Cardio Obstetrics. It provides an up-to-date and highly illustrated synopsis of the pathophysiological, biomolecular, genetic, imaging features, translational and clinical applications of cardiometabolic disease, adverse pregnancy outcomes, cardiomyopathy, ischemic heart disease, maternal shock and structural heart disease in pregnancy and their role in maternal and fetal outcomes.It relays to the reader a contemporary view of the emerging interplay between the pregnancy and cardiovascular disease and risk factors and focuses on the pathophysiology, obstetrical and cardiac management of complex disorders in pregnancy. In addition, this volume discusses the clinical implications and therapeutic targets of a wide range of diseases in pregnancy from the preventive cardiology to critical care and advanced heart failure.Contemporary Topics in Cardio-Obstetrics is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.

This volume collects 89 articles on miscellaneous topics written by Dr. William C. Roberts and colleagues between 1962 and 2016. It is part of a series of collected reprints published in 2023 gathering publications from Dr. Roberts' long career.

This volume collects 68 articles on valvular heart disease written by Dr. William C. Roberts and colleagues between 1962 and 2022. It is part of a series of collected reprints published in 2023 gathering publications from Dr. Roberts' long career.

The endothelium is a "fluid" and an ever-evolving biological component of the cardiovascular system. It plays important roles in regulating immunology, inflammation, and angiogenesis, among other functions. This book provides a comprehensive review of the endothelium, with a focus on novel aspects of endothelial dysfunction and its treatment.

In recent times, research in human-focused robot technologies aims to bring social-emotional intelligence closer, which interconnects with human lifestyles. Among several areas that can benefit from it, the healthcare sector, which consists of many possible areas of therapeutic interposition, is the most vital. Further, there is always concern about patient adherence to cardiac rehabilitation. It is essential to understand the motivational factors affecting patient participation and compliance with cardiac rehabilitation by recognizing and understanding the nature of patient experiences. Cognitive Cardiac Rehabilitation Using IoT and AI Tools describes the application of AI techniques used to extract features from brain and heart signal data and to better efficiency compared to the existing methods. This book also describes the application of AI tools to classify disorders and better performance compared to the existing benchmarks. Covering topics such as cardiac rehabilitation, heart disease prediction, and online social media analytics, this premier reference source is an excellent resource for healthcare professionals, medical engineers, hospital administrators, students and educators of higher education, researchers, and academicians.

In medizinischen, psychologischen, musik- und pflegewissenschaftlichen Studien wurde mehrfach der Einfluss von Musik auf Angst und Schmerzempfinden bei operativen und nicht-operativen Behandlungen untersucht. Im Gegensatz dazu wird in diesem Buch der Frage nachgegangen, ob Musik bei einem mit Anspannung erwarteten medizinischen Eingriff einen belastungsreduzierenden Effekt generiert (zu positiven Veränderungen in der psychischen und physischen Anspannung führt) und ob verschiedene Musikgenres ("Tanz- und Unterhaltungsmusik", "Musik zum Träumen", "Meditations- und Entspannungsmusik") zu unterschiedlichen Ergebnissen führen. Zudem wird der Zusammenhang zwischen psychischer und physischer Anspannung beschrieben sowie der Einfluss der soziodemographischen Variablen Geschlecht, Alter, Familien- und Berufsstand, Bildung und Elternrolle.Als Indikator für die psychische Anspannung wurde die ¿Aktuelle Beanspruchung¿ und ¿Momentane Befindlichkeit¿ (Stimmungslage) erfasst, sowie Blutdruck (Systole/Diastole), Herzfrequenz und elektrodermale Aktivität (EDA; Hautleitfähigkeit) als Indikator für die physische Anspannung. Die Datenerhebung erfolgte zu mehreren Zeitpunkten. Die Ergebnisse zeigten, dass sich durch Musikeinspielung (unmittelbar vor dem medizinischen Eingriff) die psychische Anspannung und körperliche Belastung signifikant reduzieren lässt, unabhängig von Musikgenre, Geschlecht und Alter. Details dazu werden im Buch ausführlich beschrieben und diskutiert.

Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. With an estimated 80% of people with diabetes living in disadvantaged regions, and the key roles of lipoproteins in the pathogenesis of the chronic complications of diabetes, this volume will be relevant to many readers globally. It is our intention that the contents will advance knowledge of the readers who will use it to contribute to the reduction of the burden associated with altered lipoproteins in people with diabetes. The second edition of this book provides an updated and comprehensive review of the field. The book, which includes many tables and figures, is presented in three main sections: (i) Lipoprotein metabolism, qualitative changes and measurements; (ii) Lipoproteins and the complications of diabetes; and (iii) the treatment of lipoproteins in diabetes. Each chapter from the first edition has been updated, and new topics added. New topicsinclude the links between glycemia and lipoproteins, the role of lipoproteins in ischemic stroke, the diagnosis and management of statin intolerance (which is thought to be more common in people with diabetes) and the use of PCSK9 inhibitors and fish oils in the management of lipoproteins in people with diabetes. This book is written by an international group of experts in the clinical, laboratory and research aspects of lipoproteins in diabetes. Lipoproteins in Diabetes Mellitus, 2nd Edition is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It is a must-have resource for primary care and specialist clinicians, clinical and basic science researchers and to trainees and students.