Nuklearmedicin

Combining informative, meticulously crafted prose with more than 4,000 high-quality images, Osborn's Brain, third edition, is a comprehensive, easy to understand, and visually stunning learning curriculum from highly esteemed author Dr. Anne G. Osborn. This fully revised edition provides a solid framework for understanding the complex subject of brain imaging, integrating relevant information from Dr. Osborn's entire career of accumulated knowledge, experience, and interest in neuropathology, neurosurgery, and clinical neurosciences. While neuroradiologists will find intriguing, thought-provoking insights included especially for them in every chapter, Osborn's Brain is an excellent review resource for physicians at all levels of expertise-from seasoned radiologists and neurosurgeons to new and senior residents or fellows. Combines essential anatomy with gross pathology and imaging, clearly demonstrating why and how diseases appear the way they do and helping readers think clearly about diagnoses, types of diagnoses, and the various pathologies that can affect the brain Guides readers through the "must know" aspects of neuroimaging and neuropathology (brain trauma, stroke, vascular lesions, etc.) before zeroing in on such topics as infections, demyelinating and inflammatory diseases, neoplasms, toxic-metabolic-degenerative disorders, and congenital brain malformations Provides state-of-the-art coverage on such topics as new brain tumor entities, the effects of emerging viral illness such as COVID-19 on the brain, and recently delineated/named diseases (e.g., HIV-associated CD8 encephalitis) Features more than 4,000 stunning, high-resolution radiologic images and 100+ detailed, full-color medical illustrations, all of which are annotated to describe the most clinically significant features; and includes robust, digital-only galleries that contain hundreds of additional images that further illustrate each chapter Includes up-to-date nomenclature based on the 5th edition of the WHO Classification of Tumors, Central Nervous System, including a complete revision, expansion, and updating of CNS neoplasms with new entities, revised grading criteria, diagnostic molecular pathology, and nomenclature Contains Dr. Osborn’s trademark summary boxes for a quick review of essential facts, signature graphics with additional radiological and pathologic correlations, and up-to-the-minute literature references Includes an eBook version¿that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Contains 12 relevant, practice-oriented topics including theragnostics trials; neuroendocrine tumors: diagnostics; prostate-specific membrane antigen: diagnostics; theragnostics: post-therapy imaging; fibroblast-activation-protein inhibitors (FAPI) theragnostics; and more.Provides in-depth clinical reviews on theragnostics, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.In this issue of PET Clinics, guest editors Drs. Andrei Iagaru and Heather A. Jacene bring their considerable expertise to the topic of Theragnostics. Top experts in the field discuss neuroendocrine tumors: beta-labeled peptides; prostate-specific membrane antigen: interpretation criteria, standardized reporting and the use of artificial intelligence; prostate cancer (gastrin-releasing peptide receptor); selective internal radiation therapy; future directions in theragnostics; and more.

This book addresses X-Ray Imaging Systems intended for biomedical engineering technology students and practitioners, and deals with the major technical components of x-ray imaging modalities. These modalities include film-based imaging, digital radiography, and computed tomography. Furthermore, principles and concepts essential to the understanding of how these modalities function will be described. These include fundamental radiation physics, imaging informatics, quality control, and radiation protection considerations.X-Ray Imaging Systems for Biomedical Engineering Technology: An Essential Guide is intended for biomedical engineering technologists, who provide technical advice and services relating to digital radiography and CT departments not only in hospitals but in private facilities as well. Students in radiological technology programs may also find this to be a useful resource.

Now in its 3rd edition with new and revised content! This book is the premier resource for interpretation of computed tomography (CT) for non-radiologists! This book provides a basic introduction to the interpretation of CT imaging for non-radiology medical professionals. The book covers the fundamentals of CT diagnosis, including the key findings to make diagnoses, relevant anatomy, pathology and current treatments. The authors also provide guidance on interpreting CT images, with chapters devoted to specific anatomical regions, such as the head, neck, chest, spine, abdomen, and pelvis. The book emphasizes the power of CT imaging to diagnose pathology which directs treatment planning. Overall, CT for the Non-Radiologist serves as the essential resource for medical professionals who may encounter CT images in their practice but do not have specialized training in radiology. This is the Essential CT Study Guide!

This book presents artificial intelligence applications that may help in detecting disease, defining tissue characterization (benign vs malignant), staging and correlation with molecular biomarkers. Originally positioned as a means for noninvasive molecular phenotyping and quantification in the 1970s, PET's technological improvements in the 2000s generated renewed interest in quantification, which has grown over the last five years. This progress is parallel with the development of Artificial intelligence (AI) systems for Oncology which aim at providing the best possible treatment to patients suffering from lung, breast, brain, prostate, liver and other types of cancer.The chapters provide an overview of the use of AI in PET/CT imaging for various types of cancer, and it will be an invaluable tool especially for nuclear medicine physicians and oncologists.

This casebook details key information and findings in PET oncology imaging. PET CT has been increasingly utilized in clinical practice for diagnostic evaluation, initial staging and restaging of malignancies, and plays an important role in optimal patient care. Although F-18 fluorodeoxyglucose (FDG) is still the dominant radioactive tracer in oncology PET imaging services, a handful of new tracers have recently gained the US FDA approval, such as Ga-68 or Cu-64 DOTATATE for carcinoid/neuroendocrine tumors, and F-18 Fluciclovine (AXUMIN) and PSMA for recurrent or metastatic prostate cancers. Clinical interpretation of PET CT oncology scans is often challenging, due to the specific nature of these positron emission radioactive tracers, variable background tracer activities in different organs/tissues with normal variants, complex tumor biology, and wide-ranged treatment responses, especially with emerging and new molecular and immune therapy agents. This book serves as a hands-on casebook on how to interpret oncologic PET CT studies in clinical services with a special emphasis on phenotypic nature of oncologic imaging.Clinical cases are presented in a way that is familiar to physicians from their training in nuclear medicine services. Each case starts with key clinical information or background, followed by well-displayed PET CT images, along with pertinent questions highlighting the key findings and explanation, as well as the importance in diagnosis and clinical implications on separate pages. Clinical and imaging key findings and final impressions are highlighted throughout along with qualitative and quantitative demonstrations of phenotypic nature of modern PET imaging.Written by two nuclear medicine PET specialists with decades of first-hand clinical experience, this is an ideal guide for nuclear medicine attending physicians, diagnostic radiologists, medical and surgical oncologists, and relevant trainees.

This book is a clinically oriented, up-to-date, and in-depth review of the various applications of FDG-PET/CT and PET/MR in cardiovascular diseases with emphasis on the current available evidence. Positron emission tomography (PET) imaging with fluorodeoxyglucose (FDG) has seen increased applications in cardiovascular diseases over the last decades. Its utility is already established in a wide range of conditions, including myocardial viability imaging, assessment of inflammatory diseases such as sarcoidosis and vasculitis, as well as imaging of infectious processes, such as infective endocarditis and cardiac implantable electronic device infection. In addition, there are several emerging indications such as the imaging of left ventricular assisting device infection and native valve endocarditis as well as new applications under investigation.The first section of the book reviews the technical basis of cardiovascular PET/CT and PET/MR imaging as well as cardiac metabolism. The following chapters each present specific pathologies, presenting epidemiology, pathophysiology, and diagnostic strategies, along with high quality clinical cases to support the discussion. The final chapter is a review of 15 interesting and clinically relevant cases.This is an ideal guide for nuclear medicine physicians, cardiologists, radiologists, residents, post-graduate fellows, and technologists.

Comparing Nuclear Propulsion Technologies for Crewed Missions to MarsCurrent chemical propulsion systems are limited in their ability to support crewed missions to Mars due to their low propellant efficiency and long mission times. Nuclear propulsion technologies offer a potential solution to these challenges, as they are capable of producing higher thrust and propellant efficiency than chemical rockets.This paper compares three nuclear propulsion technologies for crewed missions to Mars: nuclear electric propulsion (NEP), nuclear thermal propulsion (NTP), and nuclear fusion propulsion (NFP). Each technology has its own advantages and disadvantages, and the best choice for a crewed Mars mission will depend on a number of factors, including mission requirements, cost, and risk.NEP systems are the most mature of the three technologies, and they have already been used successfully in a number of space missions. NEP systems use a nuclear reactor to generate electricity, which is then used to power an electric thruster. NEP systems are very efficient, but they produce relatively low thrust. As a result, NEP systems require longer mission times than other nuclear propulsion technologies.NTP systems are less mature than NEP systems, but they offer the potential for higher thrust and shorter mission times. NTP systems use a nuclear reactor to heat a propellant gas, which is then expelled through a nozzle to produce thrust. NTP systems are more efficient than chemical rockets, but they are also more complex and expensive to develop.NFP systems are the most advanced of the three technologies, but they are also the most speculative. NFP systems would use the fusion of atomic nuclei to generate energy, which could then be used to power a variety of propulsion systems. NFP systems have the potential to offer even higher thrust and shorter mission times than NTP systems, but they are still in the early stages of development.

This book is mainly intended for residents and young physicians in Nuclear Medicine, Oncology and Gynaecology, as well as other professionals interested in this area. It covers the application of several relevant nuclear medicine procedures for malignancies affecting the female reproductive system and the breast. To date, there has never been a nuclear medicine textbook specifically focused on this topic, which this work seeks to remedy. In recent years, certain nuclear medicine procedures have proven to be extremely valuable for the diagnosis and staging of gynaecological malignancies and breast cancer. The book provides a comprehensive and structured review of these procedures, accompanied by a summary of the respective issues, making it a valuable asset for students, instructors and practitioners alike.

This open access book provides basic concepts on Integrated Diagnostics and Theranostics with special emphasis on different human thyroid diseases. Thyroid diseases are increasingly detected (incidentally in many cases) but are clinically negligible in a significant proportion of patients. Accordingly, it is urgent to move from the simple disease detection to a reliable disease characterization in order to concentrate efforts on patients in need of tailored disease management. The current scenario of in vitro and in vivo diagnostics, is fastly moving toward the Integrated Diagnostics (i.e. convergence of imaging, pathology and laboratory tests with advanced information technology). Furthermore, the integration of different information will aid clinicians to properly select treatments and stratify patients¿ prognosis over time. Theranostics is a perfect paradigm of such integrated approach and radioiodine, indicated for benign and malignant thyroid disease management, was the first and is still the mostly used theranostic agent in medicine.Featuring basics concepts and clinical cases discussions the Atlas will be an invaluable tool for clinicians, laboratory specialists, imaging physicians and biomedical technologists involved in diagnosis and therapy of thyroid diseases.

This detailed volume explores key concepts and experimental design related to Positron Emission Tomography (PET) imaging that have revolutionized our understanding of human biology. The first part focuses on recent advances in radiotracer probe development to enable the detection of materials, from large macromolecules to complicated drug-like structures. The next section describes how key physiological and pathophysiological processes can be interrogated and quantifiably measured with this imaging technique. Finally, chapters examine important technological developments in the field that are revolutionizing the way these innovative PET probes are utilized in the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Positron Emission Tomography: Methods and Protocols serves as an ideal guide for researchers looking to use imaging to revolutionize the way we diagnose and treat disease.

The aim of this book is to provide crisp information related to pathology, management and radiological/molecular imaging in breast carcinoma, along with detailed information on FDG PET-CT in breast cancer, normal variants, artefacts, pitfalls with atlas illustrations. The book is unique in providing quick reference to practice of PET/CT in breast cancer. The initial few chapters are related to the pathology and management of breast carcinoma to help understand the pathophysiology of breast cancer before going to the imaging. The chapter on imaging in breast cancer highlights the role of different imaging modalities for different indications to the reader. The last four chapters describe in detail the role, normal variants, artefacts and pitfalls of FDG PET/CT along with recent molecular imaging advances in breast cancer.Written by Pathology, Oncology, Radiology and Nuclear Medicine experts from different countries with enormous experience in breast cancer practice, the book addresses nuclear medicine physicians and radiologists, but it may be of interest to a wider medical community, including oncologists and radiotherapists.

Cochlear implantation, a hybrid intervention from medical engineering, comprises one of the most advanced, life-changing surgeries of ENT. The candidacy for cochlear implantation and the road map to this surgery is hugely dependent on radiology. The Textbook of Radiology for Cochlear Implants deals with various aspects of radiology in this field. With hundreds of photographs of radiology of temporal bone, the book takes the reader through a journey to understand the temporal bone and its pathologies radiologically, with beautifully colored scans for better understanding. Various sections of CT and MRI have been color-marked by the authors to make them more vivid. This book will aid in laying a strong foundation for surgeons interested in pursuing their career in otology, specially cochlear implants. Highlights: Color-coded sections of CT and MRI All aspects of preoperative, intraoperative, and postoperative radiology covered Detailed explanation with pictographic representations of various inner ear anomalies Step-by-step methodical reading of CT and MRI of temporal bone important for cochlear implant surgery This book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

Make efficient, accurate diagnoses and prepare for imaging exams with a multitude of differential diagnoses accompanied by hundreds of high-quality, unknown cases in neuroradiology. Neuroradiology: Key Differential Diagnoses and Clinical Questions, 2nd Edition, helps you master the skills you need for interpreting imaging of the head, neck, brain and spine for adults and children. All-new cases and extensively revised content throughout bring you up to date and equip you to reach a definitive diagnosis for common, complex, and rare cases. Applies pattern analysis techniques to distinguish similar-looking diagnostic considerations.  Shows how diagnostic ambiguities are resolved by comparing and contrasting different entities.  Includes numerous new differential diagnoses.  Provides new and extensively revised content on pediatric neuroradiology, including more complex cases such as symmetric diffusion abnormality in an infant, cortical malformations, and complex spinal dysraphism.  Helps you avoid diagnostic pitfalls by recognizing significant variations in the clinical presentation of different diseases.  An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.