Bioetik

This volume captures the recent changes and evolution in ethics in research involving humans and provides future directions to achieve alternative drug development strategies for equitable global health. It presents ethical considerations in current day clinical trials and new trends of ethics in research. It also describes the historical context, illustrates the process in alternative paradigms to achieve democracy after World War II, how the framework of ethics in research was established in different regions, and policies implemented to protect research participants from the exploitation of new drug development. The book is organized into three themed parts: relevant constructions from Brazil, South Africa, Taiwan, South Korea, and Japan; historical and international perspectives of principles of ethics in research; and alternative frameworks of clinical development and innovation. Ethical Innovation for Global Health: Pandemic, Democracy and Ethics in Research is an informative resource for academic researchers, the global pharmaceutical industry, regulators, civil society and other role players involved in global health. It is contributed to by leaders in global policy development in research ethics, and experts in drug development activities with its trajectory being global health. The COVID-19 pandemic, as a global disaster, necessitated not only socio-economic but also cultural transformation. While effective vaccines were developed under a successful new methodology, there remains inequity of distribution of these vaccines globally. The book re-engages with the notion of the primacy of distributing results of scientific innovation to those who most require the benefits.

This book deals with the theme of creativity in the animal world, conceived as a basic function for adapting to specific situations and as a source of innovations and inventions. Creativity is a fundamental resource for the individual who always has a leading role in conduct. To explain creativity, the book focuses on the concept of animal subjectivity, providing a new explanatory model of behavior capable of overcoming the image of the animal moved by automatisms. This model does not use consciousness as a necessary condition, but is based: 1) on affective components, such as behavioral motives, and 2) cognitive, as tools used by the subject to carry out his purposes. Particular attention is paid to the learning processes showing the subjective character of the experience. One topic addressed is the role of creativity in the evolution of living beings: how an invention, by modifying the niche characteristics, is able to change the selective pressures and the trajectory of phylogeny. Roberto Marchesini explains that creativity is a factor that is anything but rare or exceptional in the animal world¿it constitutes a fundamental quality for many aspects of animal life.

The contributed volume "e;Multidisciplinarity and Interdisciplinarity in Health"e; is a health-centered volume of the Integrated Science Book series. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization can become obstacles to successful communication. This volume establishes how extensive is the interface between formal sciences and medical sciences on health-related issues. The book provides an overview of the value of the integration of formal, biological, and medical sciences and related products, i.e., health informatics and biomedical engineering, to frame a holistic approach to health systems, healthcare, medical practice, drug discovery, and medical device design. The book also focuses on innovative solutions to the most critical issues of different health crisis, including obesity, infectious outbreaks, and cancer that can be found by using an integrative approach. It also contains the fascinating crossroads between medical sciences, physics, and mind that is discussed from multiple perspectives on cognition, neuroscience, and psychiatry. These multidisciplinary considerations will expand the concepts of creativity, leadership, aesthetics, empathy and mental health.   

This book, written both for a Canadian and an international readership, provides a multidisciplinary review of the framework and performance of the Canadian Medical Assistance in Dying (MAID) program. In the first five years (2015-2021) of operation, this program delivered voluntary euthanasia and assistance in suicide to over 30,000 Canadian residents, presently representing a 30% annual growth. Looking back on these first five years, the 30 Canadian scholars and clinicians contributing to this volume raise important issues and attempt to answer key questions that have arisen in regards to its operation and its stated objectives. This volume strikes the most appropriate balance between the autonomy of persons who seek medical assistance, versus the interests and protection of vulnerable persons. Finally, the book makes suggestions on how the program can presently be improved. It identifies gaps in knowledge about MAID¿s operational program and its impact on individuals, families and society in order to stimulate the necessary research that is essential to the evolution of a healthy and well-balanced program. As a first, comprehensive examination of medically assisted deaths in Canada, this publication will be of great value to lay, professional, academic, political audiences both domestically and internationally, especially in jurisdictions that are examining their options of permitting assisted deaths.

This book serves as an introduction to the concepts of medical biotechnology, with great details about fundamentals and early disciplines of study as well as emerging fields and the latest research. The book follows a chronological order from the earliest discoveries and breakthroughs of medical biotechnology to the latest areas of study. The book contains up-to-date citations for each chapter and section, which makes it easy for the reader to understand the concept and also to follow the latest developments in the particular area. It is an ideal book for undergraduate and graduate students who aspire to derive basic knowledge and are also keen on learning about the latest advancements in the field of medical biotechnology. 

This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes.The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios.At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy.  The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.

The Handbook of Bioethical Decisions Volume II addresses and analyzes the most important ethical concerns and moral quandaries related to scientific integrity and institutional ethics. It counts on two parts, Part One: Research Ethics, which addresses issues related to Scientific Integrity, Research Misconduct and Conducting Ethical Research, and Part Two: Institutional Ethics and Bioethics Committees, which explores Institutional Ethics issues, Ethics and Bioethics Committees¿ roles and scopes, and Bioethical Issues in Institutional Ethics. Consequently, the Handbook, Vol. II, offers a remarkable collection of works by outstanding international experts on institutional and research ethics, in order for bioethics practitioners to obtain better elements to address key issues related to integrity in research as well as to decision-making processes. In this fashion, this volume is a valuable resource for professionals working on different bioethical and biomedical fields, such as, ethics and bioethics committees, health care institutions, biomedical and pharmacological companies, and academic settings, among others.Chapter 26 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book offers intriguing philosophical inquiries into biotechnological art and the life sciences, addressing their convergences as well as their epistemic and functional divergences. Rooted on a thorough understanding of the history of philosophy, this work builds on critical and ontological thought to interpret the concept of life that underscores first-hand dealings with matter and experimentation. The book breaks new ground on the issue of animality and delivers fresh posthumanist perspectives on the topics addressed. The authors embark on a deep ontological probe of the concept of medium as communication-bridging and life-bearing. They also take on the concept of performativity as biotechnological art.The book includes concrete, well-documented case studies and shows how certain narratives and practices directly impact ideas surrounding science and technologies. It will interest philosophers in art and technology, aesthetics, ontology, and the life sciences. It will also engage art practitioners in art and science, curators and researchers.

With an ever-growing body of evidence on the links between different oppressions, never have the debates in Critical Animal Studies surrounding intersectionality in relation to animal ethics been more important. In particular, the arguments related to anthropomorphic attributes of mentality to other than humans promise to provide fruitful new ground for re-assessing human-animal relations. This book maps the central debates surrounding anthropomorphism in relation to our descriptions of animals, their lives, animal mentality, and meaningful communication in the nonhuman world. Rebekah Humphreys synthesizes the work of critical animal theorists, philosophers, and cognitive ethologists, and provides a critical account of how the debates concerning anthropomorphism play a key role in a proper understanding of animal ethics.

The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this work seeks to engender dense ethical epistemology scientists can count on when conducting latest generation biomedical research. By bringing together an impressive array of contributions on the most important elements and categories for ¿at the bench¿ bioethical decisions as well as offering chapters by some of the most world renowned and prominent experts in bioethics, the Handbook, Vol. I, is a paradigmatic text in its area and a valuable resource for courses on bioethics, and biomedical research, as well as courses that discuss ethics and the biosciences at different professional levels, biomedical industry, pharmacological companies and the public sphere in general.

This book provides a critical and innovative reassessment of contemporary debate on the human-animal relationship. Starting with a critique of the ¿official philosophical narration¿ of animal studies, and then a reassessment of Descartes' animal-machine paradigm, Simone Ghelli tracks down the conceptual coordinates of what he calls ¿the paradigm of the suffering animal.¿ The suffering animal is a materialist thesis on the condition of the living, which, while contesting the metaphysical and anthropocentric structure of western axiology, eventually redefines and re-establishes ethics on the experience of suffering, that is on the mutual compassion sentient beings feel before the unjust sight of their finitude. The suffering animal paradigm shows how, within our philosophical tradition, the animal question has been always intertwined with the questions of atheism and of materialism. The ultimate aim of this research is to define the ¿ethical equilibrium¿ between aspects of the living,such as weakness and power, joy and suffering, life and death, which our philosophical tradition largely tends to consider as mutually excluding. To overcome such oppositions means avoiding opposing, in our ethical and political discourse, the defense of the vulnerability of the weak and the freedom of the powerful.

This booklet was developed as part of an advisory assistance project by the German Institute for Biodiversity Network (ibn) as part of a capacity building project by the German Federal Agency for Nature Conservation and the German Environmental Agency through funds from the German Federal Ministry for the Environment, Nature Conservation, Nuclear Safety and Consumer Protection. It is an introduction to the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) for anybody who is interested in the structure, work and products of this platform. As IPBES is an active body and working permanently, any overview of products and ongoing activities can only reflect the status quo at a given point in time. This second edition of the booklet reports on the status of mid-2022, after the 9th plenary session of IPBES.

Supererogation is the category of moral actions which go beyond the call of duty. This collection of articles is the first of its kind to cover the broad spectrum of issues related to supererogation. It provides an up-to-date status of the discussion on the main issues, alternative analyses, and controversies regarding central cases of supererogation. The work explores a broad range of philosophical problems and challenges our presuppositions about the basis of ethical theories. Beyond the challenges of supererogation to deontological and utilitarian views, this book presents the latest developments in the way virtue ethics approaches supererogation. It also discusses the issue of whether there is a negative analogue to the supererogatory: the suberogatory. The Handbook consists also of the first systematic discussion of supererogation from the point of view of five religions as well as a feminist analysis of the concept. The book is an essential read for philosophy scholars interested in moral philosophy.

This study was carried out with the aim of developing the knowledge on the distribution of distribution of the Berber cedar and the Atlas cypress in the Tazekka national park.The objective of this comparative study between these two species of the same family Cupressaceae is to help students, researchers and naturalists in their research and will interest all those who would like to make the quick distinction between the Thuja and the Cypress in the field.In this document, the reader will find the general characteristics of each species, its distribution as well as its uses as food, industrial and medicinal plants.This study requires further scientific research in the laboratory for a better knowledge of these two forest species.

"e;Doubt is our product,"e; a cigarette executive once observed, "e;since it is the best means of competing with the 'body of fact' that exists in the minds of the general public. It is also the means of establishing a controversy."e;In this eye-opening expose, David Michaels reveals how the tobacco industry's duplicitous tactics spawned a multimillion dollar industry that is dismantling public health safeguards. Product defense consultants, he argues, have increasingly skewed the scientific literature, manufactured and magnified scientific uncertainty, and influenced policy decisions to the advantage of polluters and the manufacturers of dangerous products. To keep the public confused about the hazards posed by global warming, second-hand smoke, asbestos, lead, plastics, and many other toxic materials, industry executives have hired unscrupulous scientists and lobbyists to dispute scientific evidence about health risks. In doing so, they have not only delayed action on specific hazards, but they have constructed barriers to make it harder for lawmakers, government agencies, and courts to respond to future threats. The Orwellian strategy of dismissing research conducted by the scientific community as "e;junk science"e; and elevating science conducted by product defense specialists to "e;sound science"e; status also creates confusion about the very nature of scientific inquiry and undermines the public's confidence in science's ability to address public health and environmental concerns Such reckless practices have long existed, but Michaels argues that the Bush administration deepened the dysfunction by virtually handing over regulatory agencies to the very corporate powers whose products and behavior they are charged with overseeing. In Doubt Is Their Product Michaels proves, beyond a doubt, that our regulatory system has been broken. He offers concrete, workable suggestions for how it can be restored by taking the politics out of science and ensuring that concern for public safety, rather than private profits, guides our regulatory policy. Named one of the best Sci-Tech books of 2008 by Library Journal!

We are currently engaged in an existential species war against nonhuman animals. This book argues that, during this war, nonhuman animals should be granted legal personhood and treated as ¿protected persons¿ rather than the property of ¿protected persons.¿ The main argument is that War Crimes and Crimes against Humanity ¿ rape, forced pregnancy and other acts of sexual violence ¿ are being committed within the meat, egg and dairy industries. Avoiding ¿dreaded comparisons¿, the book explores shared sources of oppression between human and nonhuman animals who are subject to the expressions and consequences of reproductive violence. It asks: what drives and facilitates the war against nonhuman animals? And what are the global consequences of this war? Throughout, it demonstrates how racism, sexism, and speciesism informs both intrahuman violence and the violence(s) of the animal-industrial complex. Ultimately the book asks us to reconsider what it means to be human.

Reading Slaughter: Abattoir Fictions, Space, and Empathy in Late Modernity examines literary depictions of slaughterhouses from the development of the industrial abattoir in the late nineteenth century to today. The book focuses on how increasing and ongoing isolation and concealment of slaughter from the surrounding society affects readings and depictions of slaughter and abattoirs in literature, and on the degree to which depictions of animals being slaughtered creates an avenue for empathic reactions in the reader or the opportunity for reflections on human-animal relations. Through chapters on abattoir fictions in relation to narrative empathy, anthropomorphism, urban spaces, rural spaces, human identities and horror fiction, Sune Borkfelt contributes to debates in literary animal studies, human-animal studies and beyond.

This book presents an important reflection on the concept and limits of the Fundamental Right to Health as opposed to a supposed ¿Right to Hope¿ in the context of the treatment of patients with advanced cancer. The central idea of the work is the question of whether and to what extent patients with advanced cancer have the right to legally demand a palliative treatment whose efficacy has not been proven from the point of view of the desired objectives. The book demonstrates how hope cannot be subject to legal protection and, also, that, even if theoretical-legal reasons were not sufficient for the absence of an abstract right to hope, ethical reasons would be. The work concludes that the best palliative care, rather than palliative treatment, guarantees the best right to health for advanced cancer patients, especially in terminal cases.In addition to this theoretical discussion, the book also presents the results of a qualitative research the author conducted with 48 advancedcancer patients in Brazil and Germany to investigate their expectations towards chemotherapy. This study has confirmed that many patients decide to undergo often toxic and exhausting treatments, unrealistically believing that their cancer is curable or that, as long as they continue with a course of chemotherapy, cancer may be beaten. Palliative Treatment for Advanced Cancer Patients: Can Hope Be a Right? will be of interest to health professionals and social workers working with advanced cancer patients, as well as to researchers in the fields of public health, bioethics, medical ethics and health law, especially those interested in the growing interdisciplinary field of end-of-life decision-making.

This edited book analyses how artists, authors, and cultural practitioners have responded to and represented episodes of epidemics/pandemics through history. Covering a broad range of notable epidemics/pandemics (black death, cholera, Influenza, AIDS, Ebola, COVID-19), the chapters examine the cultural representations of epidemics and pandemics in different contexts, periods, languages, media, and genres. Interdisciplinary in nature and drawing on perspectives from medicine, literature, medical anthropology, philosophy of medicine, and cultural theory, the book investigates and emphasizes the urgent need to reflect on past catastrophes caused by such outbreaks. By delving into cultural history, it re-examines how societies and communities have responded in the past to species-threatening epidemics/pandemics. Sure to be of interest to lay readers as well as students and researchers, this work situates epidemics and pandemics outbreaks within the contexts of culture and narrative, and their complex and layered representation, commenting on intersections of contagion, culture, and community. It offers a cross-cultural, global, and comparative analysis of the trajectories, histories and responses to various epidemics/pandemics that impacted people worldwide.

This volume discusses the definitional problems and conceptual strategies involved in defining the human. By crossing the boundaries of disciplines and themes, it offers a transdisciplinary platform for exploring the new ideas of the human and adjusting to the dynamic in which we are plunged. The emerging cyborgs and transhumans call for an urgent reconsideration of humans as individuals and collectives. The identity of the human in the 21st century eludes definitions underpinned by simplifying and simplified dichotomies. Affecting all the spheres of life, the discoveries and achievements of recent decades have challenged the bipolar categorizations of human/nonhuman and human/machine, real/virtual and thus opened the door to transdisciplinary considerations. Ours is a new world where the boundaries of normality and abnormality, a legacy of the long history of philosophy, medicine, and science need dismantling. We are now on our way to re-examine, re-understand, and re-describe what normal-abnormal, human-nonhuman, and I-we-they mean. We find ourselves facing what resembles the liminal stage of a global ritual, a stage of being in-between¿between the old anthropocentric order and a new position of blurred boundaries. The volume addresses philosophical, bioethical, sociological, and cognitive approaches developed to transcend the binaries of human-nonhuman, natural-artificial, individual-collective, and real-virtual.

Roadkill is a recurrent but often unthought feature of modern life. Yet, consideration of the broader significance of the myriad social, ethical, and political issues related to roadkill has largely gone missing from mainstream scholarship and activism. This neglect persists even in fields such as mobility studies and animal studies that would otherwise seem to have a vested interest in the topic. This book aims to bring roadkill to the foreground of current discussions among scholars and activists in these fields in order to demonstrate that roadkill is a uniquely important site from which to understand and contest the machinations of the dominant social order. It argues that a careful examination of roadkill can help both to uncover the hidden violence of contemporary human-centered systems of mobility and to develop alternative modes of mobility for a renewed social life in common with our more-than-human kin.

In this open access book, Angela K. Martin thoroughly addresses what human and animal vulnerability are, how and why they matter from a moral point of view, and how they compare to each other. By first defining universal and situational human vulnerability, Martin lays the groundwork for investigating whether sentient nonhuman animals can also qualify as vulnerable beings. She then takes a closer look at three different contexts of animal vulnerability: animals used as a source of food, animals used in research, and the fate of wild animals.

The Covid pandemic has led us into an upheaval that has made us question the certainties underlying what it means to be a human being in our age; the ability to control medical and social facts through evidence. For the first-time western and developed countries have had to confront what many populations from the developing world (Africa. Latin America, etc) face on a daily basis with HIV and Ebola, etc. The Interconnectedness of Globalization has been the real disseminating catalyst of COVID 19, and many scientists wonder if this virus is the result of the Anthropocene age, with its indisputable lack of respect for the natural ecosystems.  The virus has demonstrated that our frailty is only skin deep, and it has not only brought death, despair, but it has broken our interdependency as human beings, by imposing self- isolation as well as creating new ways of connections so that safety cannot imply loneliness. In this book, the coping strategies that originate from the multiple languages of care such as narrative, literature, science, philosophy, art, digital science are shown not only as reflective tools to promote health but also wellbeing amongst carers, patients, students, and citizens of our planet Earth. These strategies should be supported by the decision makers since they are low-cost investments necessary to make the health care system work. They however require a change of cultural paradigm. This book is a useful toolkit for patients, citizens and care services physicians who want to learn more on how to live better with this new world.  

This book highlights the latest findings and techniques related to nutrition and feed efficiency in animal agriculture. It addresses the key challenges facing the nutrition industry to achieve high animal productivity with minimal environmental impact. The concept of smart nutrition involves the use of smart technologies in the feeding and management of livestock.The first chapters focus on advances in biological fields such as molecular agriculture and genotype selection, as well as technologies that enhance or enable the collection of relevant information. The next section highlights applications of smart nutrition in a variety of livestock systems, ranging from intensive indoor housing of broilers and pigs to extensive outdoor housing of cattle and sheep, and marine fish farms. Finally, because of the worldwide attention to this issue, the authors address the environmental consequences.This work, which takes a serious look at how nutrition can be usedto improve sustainability in animal agriculture, is a key literature for readers in animal and veterinary sciences, the food industry, sustainability research, and agricultural engineering.