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Race is a social reality, not a biological one. Yet African Americans are poorly served by even advanced genetic medicine because it is built on European DNA. Constance Hilliard explores the benefits and drawbacks of racial heuristics in medicine and argues for nonessentializing methods of harnessing genomic science on behalf of people of color.
Wheat (Triticum L.), an annual herbaceous plant in Poacae (Gramineae) family, settles in the Triticeae (Hordeae) subfamily. The grasses (Poaceae Barnhart) are the fifth largest (monocotyledonous flowering) plant family and of great importance for human civilization and life. Cereal crops such as maize, wheat, rice, barley, and millet are the domesticated ones in the family. It is still the most vital economical plant family in modern times, providing food, forage, building materials (bamboo, thatch), and fuel (ethanol). Wheat has many accessions in national and international gene banks. The estimated number of wheats by FAO in 2010 is 856,000, and, followed by rice (774,000), and barley (467,000). However, the recent consumer's (misdirected) focus on gluten content and nutritional value urges scientists to reexamine their knowledge about wheat (i.e., origin, evolution, and general and special quality characteristics), as well as their wild relatives and landraces for newer possible genetic resources. Cultured or non-cultured ancestral wheats: einkorn, emmer, wild emmer, spelt, macha, and vavilovii are still limitedly grown on the higher areas in Turkey, Italy, Germany, Morocco, Israel, and Balkan countries. They are exploited mostly for their desired agronomic, and specific quality. In some cultures, wheat species are believed to be therapeutic, with bioactive compounds that reduce and inhibit stubborn illnesses such as diabetes, cancer, Alzheimer, and cardiovascular diseases. In this book, we summarize the importance of ancestral wheat species, and provide a prospect for their future with special considerations in terms of species conservation and improvement.
Non-coding RNAs (ncRNAs) are RNA molecules that are not translated into proteins. They are divided into two categories, namely, housekeeping ncRNAs and regulatory ncRNAs. The main function of the ncRNAs is to maintain the normal cell functionalities. Small RNAs, ribosomal RNAs (rRNAs), long ncRNAs and transfer RNAs are some types of non-coding RNAs, which are abundant and functionally significant. Numerous types of small and long non-coding RNAs are considered important regulators of gene expression in a variety of processes, which range from embryonic development to innate immunity. This promotion of gene expression is done by a special ncRNA named enhancer RNA, which is transcribed from the enhancer region of the gene. The human genome is encoded with thousands of small and long RNA transcripts that do not code for proteins. This book explores all the important aspects of regulatory non-coding RNAs. It will prove to be immensely beneficial to students and researchers studying this topic.
This second edition volume expands on the previous edition with new and updated chapters that highlight the latest methods and approaches for the manipulation of RNA viruses. The chapters in this book explore the fundamental role in studying RNA viruses; identifying markers of host range, disease, and transmission; and aid readers with the further development of in silico computational biology tools and artificial intelligence algorithms that can help predict the emergence of certain pathogens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Reverse Genetics of RNA Viruses: Methods and Protocols, Second Edition is a valuable resource for researchers who are interested in learning more about this developing field.
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