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Starting with protein folding and protein quality control basics, the reader will learn how misfolded proteins can cause diseases ranging from prion diseases to Alzheimer's disease and Parkinson's disease to Huntington's disease, amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
This book summarizes the functioning of complex signaling pathways in different tissues and organs of the body in both health and disease. Containing over 150 figures, it presents the latest research findings as a guide to drug design and tissue engineering.
Makes connections between diseases, drugs and signaling in those chapters not specifically devoted to pathogens. Reviews background in first 5 chapters then offers chapters on cancers and apoptosis and on bacteria and viruses.
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